pntAa
mL2636c
PROBABLE NAD(P) TRANSHYDROGENASE (SUBUNIT ALPHA) PNTAA [FIRST PART%3B CATALYTIC PART] (PYRIDINE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT ALPHA) (NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT ALPHA)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3153219 – 3154322
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2636c_pntAa_dna
GTACGTGCCATGACAGAAGCGCAAACGACGGTTGGAGTGGTCGCCGAGTCCGGTTCCGACGAGCGGCGCGTCGCTTTGGTGCCAAAGGCAGTAGCGTCTCTAGTGAACAGCGGTCTAGCGGTCGTGGTCGAGTCCGGGGCGGGCGAAGGTGCATTGCTTCCCGAGCAGCTCTACACAGAGGCCGGCGCTCGCATCGGGGACGCGTGGGCTGCCGACATCGTCGTCAAAGTGGCGCCGCCGGCTGCAGCCGAGGTCGGCCGACTGCGCCGCGGGCAGACGCTGATCGGCTTCCTTGCGTCCCGCAATGCCGACAACTGGATCGGCGAGTTGAAACGAGCTGGTGTGCAAGCGTTCGCGCTCGAGGCAATCCCGCGCATCTCGCGTGCACAAGTGATGGATGCGCTGTCGTCGCAGGCTAACGTGACCGGGTATAAAGCAGTGTTGCTTGCGGCTTCTGAGTCTACCCGATTTTTCCCGATGCTGACGACAGCTGCAGGAACGGTGAAGCCGGCCATCGTGCTGGTGCTCGGCGTCGGGGTGGCAGGTTTGCAAGCGCTGGCGACGGCCAAGCGCCTTGGCGCGCGCACCACCGGCTACGACGTGCGTCCTGAGGTGGCCGAGCAAGTCCGGTCGGTGGGTGCCCAGTGGCTTGACGTAGGAATCGAGGCTTCCGGTGCGGGCGGATACGCCCGTGAGCTCACCGCCGACGAACGCGCTCAGCAACAGAAGGCATTGGAAAAGGCGATCAGCGGATTCGACGTGGTGATTACCACAGCGCTGGTCCCGGGCAAGCCGGCACCGCGGTTGGTGACCGCTGCGGCGGTGGAGGCGATGAAGCCTGGCAGCGTGGTGGTGGACCTCGCGGGGGAAACCGGTGGCAATTGCGAGCTCACTGAACCCGGGCAGACGGTGATCAAGCATGATGTCACTATTGCGGCGCCGCTGAATCTGCCGGCAACGATGCCTGAGCACGCCAGCGAGCTCTACAGCAAGAACATCAAGGCGCTGTTGGACCTACTAATAAAGGATGGCAAGTTTGCCCCGGACTTTGACGACGAAGTCGTCGCGGAGTCATGTGTGACTCGCGATCGAGAGGACTCCATA

Protein Sequence 

>ML2636c_PntAa_protein
VRAMTEAQTTVGVVAESGSDERRVALVPKAVASLVNSGLAVVVESGAGEGALLPEQLYTEAGARIGDAWAADIVVKVAPPAAAEVGRLRRGQTLIGFLASRNADNWIGELKRAGVQAFALEAIPRISRAQVMDALSSQANVTGYKAVLLAASESTRFFPMLTTAAGTVKPAIVLVLGVGVAGLQALATAKRLGARTTGYDVRPEVAEQVRSVGAQWLDVGIEASGAGGYARELTADERAQQQKALEKAISGFDVVITTALVPGKPAPRLVTAAAVEAMKPGSVVVDLAGETGGNCELTEPGQTVIKHDVTIAAPLNLPATMPEHASELYSKNIKALLDLLIKDGKFAPDFDDEVVAESCVTRDREDSI

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PntAa with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

0 show intermediate predicted evidence for PPIs

19 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PntAa

Use of these data is subject to the AlphaFold Server Output Terms of Use.

You do not have permission to view notes.