pepA
mL2659c
PROBABLE SERINE PROTEASE PEPA (SERINE PROTEINASE) (MTB32A)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3182083 – 3183147
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2659c_pepA_dna
GATTACGGGATGAGCAGACAACCCCACCGTTCACTCTGGCGGTCATGGCTGGTAAGTACATTAGCTGCGCTAGGTCTGAGTCTAGCCGTGGTTCCAGGGTCAGCCACACCGTCTGGACCGTCCACTTTGGCGCTCGATCGGTTCAGCAACCGGCCACCCCTGCCGCTCAATCCCGCCGCGATGGTTGCGCCTCAGGTGGTCAATATCAGCACTAGATTAGGCTACAACAGCGCGGTGGGAGCCGGGACGGGAATCGTTATCGATTCCAGCGGTGTCGTGCTGACCAATAATCACGTGATCTCGGGTGCTACCGATATCAGTGCGTTCGATGTCGGAAATGGCAAAACTTACGGCGTCGACGTGGTTGGTTACGACCGTACCCAGGACGTCGCGGTGCTCCAGCTTCGTGGCGCGAGTAACCTGCCTACCGCAGTAATCGGTGGTGACGTGGCGATCGGCGAACCGATTGTGGCTCTGGGCAACACGGGCGGCCAGGGTGGACTTCCCAGCGTGTTGCCGGGTCGTGTCGTAGCACTTAACCAGACCGTCCAAGCGTCTGAACCCCTGACCGGCGCCCAAGAGACGTTGTCCGGACTAATCCAGGTCGACGCCCCGATCAAACCCGGCGATTCGGGCGGGCCCGTCGTCAACAGCCGAGGTCAGGTGGTCGGCATGAACACTGCTGCTACCGATAACTACAAGATGTTGGGTGGGCAGGGCTTCGCCATTCCGATTGGTCAGGCGATGGAGGTCGTCGGTGCCATCCGGTCCGGGGCTGGGTCAAACACCGTACACATAGGCCCGACGGCCTTCTTTGGCCTGGGCGTTTTAGACAACAACGGCAACGGCGCACGGGTTGCCCGTGTGGTCGCGACGGGTCCAGCCGCGATGGCTGGGATTTCGGTAGGTGACATCATCACGTCGGTCGACGGTGTACCCATCAGCGAGGCCACCGCTATGACGAATGTGCTCGTGCCGCATCATCCTGGGGAAACCGTTGCGGTGAACTATCGCTCTGCTGGCGGCGGTGACCTCACCGCGAATGTGACGTTAGCGGAGGGACCT

Protein Sequence 

>ML2659c_PepA_protein
DYGMSRQPHRSLWRSWLVSTLAALGLSLAVVPGSATPSGPSTLALDRFSNRPPLPLNPAAMVAPQVVNISTRLGYNSAVGAGTGIVIDSSGVVLTNNHVISGATDISAFDVGNGKTYGVDVVGYDRTQDVAVLQLRGASNLPTAVIGGDVAIGEPIVALGNTGGQGGLPSVLPGRVVALNQTVQASEPLTGAQETLSGLIQVDAPIKPGDSGGPVVNSRGQVVGMNTAATDNYKMLGGQGFAIPIGQAMEVVGAIRSGAGSNTVHIGPTAFFGLGVLDNNGNGARVARVVATGPAAMAGISVGDIITSVDGVPISEATAMTNVLVPHHPGETVAVNYRSAGGGDLTANVTLAEGP

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding PepA with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

3 show intermediate predicted evidence for PPIs

32 show weak predicted evidence for PPIs

View all pooled AlphaFold results for PepA

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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