ctpI
mL2671
PROBABLE CATION-TRANSPORTER ATPASE I CTPI
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3204719 – 3209548
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2671_ctpI_dna
CCGCATGTGACCGACCCCGTAAGCAATATGGTCGGCGGCATGGCGCAGGTGGTGCGGGCCAGTACGCATGCCGCCACCGGCGCTGTCAACACGATGCAGATGCTGGCCAGCCCGGTCGCCGAGTTCGCTTGGCCGGTGGTGCAATCGGTAGCTAAATCCACCGGCCGAGCGCTCGGTACGGGCCATTCACCGAATTTTGCGAACCGGGTCGATCCACCGGTGCGCTGGCACAACGGTCAGCGTGTACACCTAGACCTGGATCCGCTGCTACCGTTCCCCCGCTGGCATGAGTACGCAGCAGTAGTAGAAGAACCGGTTCGTAGAATTCCAGGGGTGGCTAAGGGCCATGTCGAGGGCTCATTGGGACGGCTAGTAATCGAACTAGACAAGAACGCGGATAGCGACGTTGTCTTGGGCAAAGTGCGTGACGTGGTTATTGCCCTGGCCGCCGACTTAGCATTGACAGGGGCGAGATCGGCCCCCAAGGTTGCTCCATTTGCCGACCCAGGTAATCCGCTGGCAATTCTTATGCCGCTAACCGCCGCGGTAATGGACCTTGTCGCGTTGAGTGCCGCAGTGACCGGCTGGGTCACCCGACTGCCCGCCGTACCGCAAACTATCCGGGCCGCGGCGGCTCTCGTCAATCATCAACCGCGCATGGTGTCACTGCTGGAATCACGACTGGGTAGGGTCGGCACCGATATTGCACTCAGCATTACAACAGCGGCGGCTAGCGGGCTGACCCAAGCGGTAGGCACACCACTGCTGGATCTGGCGTGCCGTGGCCTGCAACTCTCCGAAGCGGCGGCTCACCAGCGCGTGTGGCGAGATCGAGAGCCTCAACTGGCCTCACCCAAGCGGCCACAAGCGCCGGTGGTCCCCGTGATCTCGTCGGCAGGGGAAAAATCGCATGCCGCAGGCCACAACTGGACAGCCGCAGCGTCGAATGAAGCGTCGCACCTCGTGGTCGGCGGATCAATCGACGCCGCAATCGACACCGCAAAAGGGTCGATGAAAGGACCTGTAGAGAGCTATGTCGATTCAGCGGCAAACGGTTCGTTGATTGCCGCGGCGAGTGCTTTGCTCGCGGGCGGTGGCACCGAAGACGCGGCCGGCGCGATCCTGGCCGGGGTGCCAAGAGCGGCGCATATGGGCCAGCAAGCGTTCGCGGCGACACTGGGCCGCGGACTGGCCAACGCCGGGCAACTGGTACTCGATCCGGGTGCGCTGCGCCGCCTGGACCAGGTCAAGGTGGTCGTCATCGACGGGGCCGCATTGCGCGGTGATCACCGCGCGGTATTGCTTGCCCGGGGAAATACGCCCGGCTGGGACGACGACCGTGTATATGAGGTTACCGACGCACTGCTGCACGGCGAGCGGGCACCCGAGCCCGATCCCGACGAGTCACCGGCCACTGGAGCGCGGCTCAGATGGGTTCCGTTGCAGGGGCCGTCGGCAACACCCGTACAGGGCCGCGAGCACGCGGATCTGGTGGTTAATGGCGAGTGCGTCGGCGGTGTCGACGTCGGATGGGAAGTCGACCCCTATGCGATCCCGCTGCTGCAGACCGCACACCGAACCGGGGCACGCGTAGTCTTGCGTCATGTAGCTGGCACAGAAGATCTCTCCGCCAGCGTCGGCGCGACGCATCCGCCCGGTACACCGCTGCTGAAGTTGGTACGTGAGCTGCGCACCGATCGCGGACCGGTGTTACTGATCACCGCCGTGCACCGGGACTTCGCATCGACCGACACGCTGGCCGCACTAGCCATTGCCGACGTCGGGGTAGCCCTGGACGATCCCCATGCAGCTACACCGTGGACCGCGGACATCATCACTGGCACTGATCTGGCGGCCGCAGTGCGGATCCTGTCTGCGCTGCCCGTGGCCCGTTCAGCCAGTGAATCTTCGGTGCACCTTGCTCAGGGCGGTACTACCCTGGCAGGGCTGCTGCTGATCACCGCGAGCGCTGGTAGCAAATCCGCTAGCCCAATTACTTTGCGGCGCTGGTTTAGTCCGGTCAATGCGGCCGCAGCGACCGCATTGGTGACTGGCGTCGTCTCAGCCAGCAAGGTGCTCCGGCTGCCGGACCCTACCCCGCAACCGCTGACCGCCTGGCACGCGCTGGACCCCGAGATCGTTTACTCACGATTGGCCGGCGTCACACAACCGTTAGCCGTTGAGCCCGGTACCCCCGATTGGCGACGTCGTCTCGACGATCTGTCCTACACCCGGGCGCTGTCACCGCTGCGCAAACCAGTAACCAAACTGGCTCGGCTGGCGAGCGCGACCCGGCAGGAATTCGCCGATCCGCTGACTCCCATCCTGGCGGTCGGAGCAGCTGCGTCGGCGATCGTTGGCAGTAATATCGATGCCCTTTTGGTCGCGGGCGTGATGACGGTCAACGCGATTACCGGTGGCGTGCAACGGTTGCGGGCCGAGGCGGCCGCCGCCGAGCTGTTCGCCGAGCAGGATCAGTTGGTGCGACGCGTCGTTGTCCCGGCGGTGGCAACGACCCGTCGTCGATTGGAGGCTGCACAGCACGCCACACGGACAGTCACGGTGTCCGCCAAGTCGCTGCGAGCCGGTGATGTCATCGACCTGGCTGCTCCGGAAGTGGTACCGGCAGATGCTCGCGTGTTGGTAGCCGAAGACCTCGAAGTCGATGAGTCTTTACTCACCGGGGAGTCGTTGCCGGTGGACAAGCGAGTGGACCCCGTCGCCATCAACGACGCCGACCGAGCGAGCATGCTGTTCGAAGGCAGCGCGATCGTGGCAGGACATGCCCGCGCGATCGTGGTGGCCACCGGGGTCGGCACAGCCGCACACCGCGCGATCTCGGCTGTCGCCGACGTGGAAGTATCAGCCGGGGTGCAAGCACGGCTGCGGGAGCTGACCAGCAAGGTCCTTCCTCTGACACTGGCCGGTGGCGCCGCGGTGACGGGTTTGGCTTTGCTACGCCGCGCATCACTGCGTCAAGCAGTCGCCGATGGCGTCGCAATCGCCGTGGCCGCTGTCCCGGAGGGTCTGCCATTGGTGGCCACCCTCTCCCAGCTCGCCGCGGCCCAGCGTTTAACGGCGAAGGGGGCGCTGGTCCGATCGCCCCGCACGATCGAAGCCCTGGGCCGCGTTGACACCATATGTTTCGACAAGACAGGTACGCTCACCGAAAATCGACTGCGTGTCGTCTGTGCGGTGCCGAACACGAGGATGCCACACGATCCACTTCCCGACATCACCGATCCGCACTCTGCTGCGGTGCTGCGGGACGCCGCGCGGGCGTCCACCCAACCCCACGACGGGCAAGGCCACACGCACGCCACCGATGAAGCGATCCTCACGGCAGCCAGTTCGCTTAACAGCCATACCGATTCGACTTGGAGCCTAATTGCGGAGGTACCGTTCGAGTCCAGTCGCGGTTATGCCGCCGCGATCGGCATAACCGGCAATGGTAAGGCGCCGATGCTGATGCTCAAGGGCGCCCCTGAAAAGATCCTGCCGCGTTGCCGGTTCGCCGATCCAGAGGCCGACGTTGCTCACGCAGAGTCCTTGGTGCGCCACCTCGCCGAGCAAGGCCTGCGCGTTTTGGCGGTCGCGCAATGCTCCTGGGGCCACGACACCACCGACGATAACGACACCGATGCTGATGCCGTCGACGCTGCCGCGCATGACCTCGAGCTGGTCGGCTATATCGGACTAGCGGACACCGCACGGCCATCCTCGCGTCCGTTGATCGAAGCGTTGGTAACCGCCGGCCGCAACGTGGTACTGATAACCGGCGATCACCCCATCACCGCACGGGCTATCGCCCAGCAGTTGGGTCTGCGCTCGGATGCACGGGTAGTGAACGGCACCGAACTTATCGGCCTCGACGAGGACGCATGCGCCGAACTTGCCGCCGACGTGCAGGTCTTCGCCCGAGTCAGTCCGGAGCAAAAGGTGCAGATTGTGGCAGCGTTGCAACGCTGCGGGCAAGTGACGGCGATGGTTGGTGACGGTGCCAACGACGCCGCTGCCATCCGGATGGCCGATGTGGGCATCGGCGTGAGTGGCCGCGGTTCTTCAGCCGCCCGAGGAGCCGCTGACATCGTCTTGACCGACGACGATCTGGGTGTACTGCTCGATGCCCTGGTCGAAGGCCGCAGCATGTGGGCAGGCGTTCGTGATGCGGTCACGATTCTGGTCGGAGGCAATGTCGGCGAAGTCGTCTTTACTATCATTGGGACGGTATTCGGTGCTGGTCGGGCGCCGGTGGGAACCCGTCAACTACTGTTGGTGAACTTGCTCACCGATATGTTCCCCGCGCTTTCGATCGCTGTTACCTCGCAATACGAAGAACCCGGCGAGGACGAATATCAAACCGACGAAGAGGCAGACGAGGCGCGACGAACACACCAACACGAGGTACTGACCGGACCTACGCCCTCGCTCGACGCGCCACTGATGCGACAGATCGTCAACCGTGGTGTGGTCACGGCCGCCGGTGCGACCACAGCCTGGGCTATCGGGCGCTGGACGCCGGGTACCGAACGACGAACGGCGACAATGGGACTGACCGCATTGGTGACGACGCAGCTGGCACAGACCCTGCTCACGCGCCGACACAGCCCGCTCGTCGTAGCAACCGCACTAGGCAGCGCGGGTGTTTTGATCGGTATCATTCAAACCCCGGTAATCAGTCAGTTTTTCGGGTGCACACCGCTTGGGCCAATAGCCTGGTCAGGAGTAATAACTGCCACAGCAGGAGCCACCGCAGTCTCGGTACTGGCACCCCAGTGGTTAAACAAAGCTTTTGGTATCGCGCAACTCAATCAGGAGTGAGCATTAACC

Protein Sequence 

>ML2671_CtpI_protein
PHVTDPVSNMVGGMAQVVRASTHAATGAVNTMQMLASPVAEFAWPVVQSVAKSTGRALGTGHSPNFANRVDPPVRWHNGQRVHLDLDPLLPFPRWHEYAAVVEEPVRRIPGVAKGHVEGSLGRLVIELDKNADSDVVLGKVRDVVIALAADLALTGARSAPKVAPFADPGNPLAILMPLTAAVMDLVALSAAVTGWVTRLPAVPQTIRAAAALVNHQPRMVSLLESRLGRVGTDIALSITTAAASGLTQAVGTPLLDLACRGLQLSEAAAHQRVWRDREPQLASPKRPQAPVVPVISSAGEKSHAAGHNWTAAASNEASHLVVGGSIDAAIDTAKGSMKGPVESYVDSAANGSLIAAASALLAGGGTEDAAGAILAGVPRAAHMGQQAFAATLGRGLANAGQLVLDPGALRRLDQVKVVVIDGAALRGDHRAVLLARGNTPGWDDDRVYEVTDALLHGERAPEPDPDESPATGARLRWVPLQGPSATPVQGREHADLVVNGECVGGVDVGWEVDPYAIPLLQTAHRTGARVVLRHVAGTEDLSASVGATHPPGTPLLKLVRELRTDRGPVLLITAVHRDFASTDTLAALAIADVGVALDDPHAATPWTADIITGTDLAAAVRILSALPVARSASESSVHLAQGGTTLAGLLLITASAGSKSASPITLRRWFSPVNAAAATALVTGVVSASKVLRLPDPTPQPLTAWHALDPEIVYSRLAGVTQPLAVEPGTPDWRRRLDDLSYTRALSPLRKPVTKLARLASATRQEFADPLTPILAVGAAASAIVGSNIDALLVAGVMTVNAITGGVQRLRAEAAAAELFAEQDQLVRRVVVPAVATTRRRLEAAQHATRTVTVSAKSLRAGDVIDLAAPEVVPADARVLVAEDLEVDESLLTGESLPVDKRVDPVAINDADRASMLFEGSAIVAGHARAIVVATGVGTAAHRAISAVADVEVSAGVQARLRELTSKVLPLTLAGGAAVTGLALLRRASLRQAVADGVAIAVAAVPEGLPLVATLSQLAAAQRLTAKGALVRSPRTIEALGRVDTICFDKTGTLTENRLRVVCAVPNTRMPHDPLPDITDPHSAAVLRDAARASTQPHDGQGHTHATDEAILTAASSLNSHTDSTWSLIAEVPFESSRGYAAAIGITGNGKAPMLMLKGAPEKILPRCRFADPEADVAHAESLVRHLAEQGLRVLAVAQCSWGHDTTDDNDTDADAVDAAAHDLELVGYIGLADTARPSSRPLIEALVTAGRNVVLITGDHPITARAIAQQLGLRSDARVVNGTELIGLDEDACAELAADVQVFARVSPEQKVQIVAALQRCGQVTAMVGDGANDAAAIRMADVGIGVSGRGSSAARGAADIVLTDDDLGVLLDALVEGRSMWAGVRDAVTILVGGNVGEVVFTIIGTVFGAGRAPVGTRQLLLVNLLTDMFPALSIAVTSQYEEPGEDEYQTDEEADEARRTHQHEVLTGPTPSLDAPLMRQIVNRGVVTAAGATTAWAIGRWTPGTERRTATMGLTALVTTQLAQTLLTRRHSPLVVATALGSAGVLIGIIQTPVISQFFGCTPLGPIAWSGVITATAGATAVSVLAPQWLNKAFGIAQLNQE_ALT

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding CtpI with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

12 show intermediate predicted evidence for PPIs

177 show weak predicted evidence for PPIs

View all pooled AlphaFold results for CtpI

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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