ML2678
mL2678
LONG CONSERVED HYPOTHETICAL PROTEIN
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3222411 – 3225413
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2678_ML2678_dna
TCGGCGGCTATGAACATCAAGGTCACGCTGGAGCACCGCACTAGCTACACCTTTAACCGGCTGGTCCAGGTGTGTCCGCATGTCGTTCGGGTACACCTGGCACCACACTCACGCCCGCCTATCGAGGCCCACTCGCTGCAGATCGAGCCAGCCGGCCACTTCATCAACTGTCAGCAAGACACGCTAGGCAACGGCTTGACCCGACTGGTCTTGCCGAATCCTATGCGCCGACGGAGCATAGGATTCGGGCTCATCACCAACCTCAAGATGATCAGCCCGTTCGACTGCTATATCGAAAACTGGGCCGAGACGTGGCCTGCCACGGCCAGGTCAGGACCGACATTCACCTATCCCGAAGCGCTAGCCGAGGACCTCAAGCCTTACCTGCGGCCCGTCGACGAAGCAGGCAACCGATTCGTCGACAATGAGCTAGTGTGGGCATGGATTCGCAACTTCCCGGTGCCAGATGGCATCCGAACCATCAACTTCATCAACTTCCTGGTCGCGTTCAATCAAGCGATGAACGCCGAGGTCAGCGATATCGTGTGCATGGAACACGGTGTCCCGACAACGGATTTCACGCTGCGCACCGGCATCAGCTCGTGTCGGGACTCGGCATGGTTATTGGTATCGATTTTATGGCAGATGAGATTAACCGCCTGGGTTGTGTCCAGCTCAGCTACCTCGTACAACTGCCCTCCGATATCGAGGCACTCAACGAGCCATCGGGGCCTGCCACCGAATTCACCTACTTGCACGCCTGGACCGAAGTGTCCATCCCCTGTACGGGCAAAATCAGGCTGGACCCGATCTCGGGGCTGTTCGCCAACGAGGTCCGCATACCGTTGGCAACCACACCACATACTGCGTCGGCAGCGCCGACCAACGGCTCAACCGACCCGTGCGAAGCGGTGCTGGACTTCCCTAACATTGTCCACCCAGGTCCAAGAAGACCCGCACATCACGCTGCCTTACTCCGACGTGGCGTGGCACGCGATCTGCGCGATAGGCCAGCACGGCTACCAACGGCTGACCGTCGGCGGGAAGCCGACAGTCGTCTTGGTGAACATCCACCCGAACAAGGGCCGCAAAGAGTGGACGATGGTCGCCAAAAGCCCGTCTAAGCGCCAGCCGGCATCCGATCTTACTGCCCGGCTGAAGGCCGCCTGGGCGCCGCAGGGGCTGATCCATTTCAGACAGGGCCAGTGGTATACGGGAGAGCCGTTGCCGCAATGGCAGATTACACTGTATTGGCGCACCAAAGGACAGCCACTATGGACCAACGATGCACTGCTGACTGATACCTGGAAAGCCGGTCCAAGCGAACGAAACAAGACAACCCTTGAAGATAGCGAGCTAGCCCACAAGGTGCTAGCCCAGGCAGCTGACGGTCTCGGGTTACCACTCACACAAATGCGGGCAGCATACAAGGATACGCTGCGCCGTCTAGCAGCTAAAGTGCGGATTCCGAGCGGCGCCCCAGTGCAATTAAGTGACGACCGCGGCCCCACTACCCCGGACAGCGCCGTCAACCGTGTCGCACTGCTTACGCGTCTCGAGGAATCAGTCACCTTGCCGGACGCGTATATGCTGTCGCTGCACAGCCGTGACGACAACCTCAGCTGGGTCCAAGCAACCTTGCAGCTGCACCGCGGCTGCATTGTGCTGATCGAGGACGCTTCGCTGGCAGGCTTGCTGCTGCCGCTGGATTCGATCAGCTGGCCACGACCGCATGTGTCGTTTTACCTCGATCCGATGACCTTCTGGCGCGCGTGGTCGGCGGAACCCAACACCGCCGCAGCTGTGCTCGAGAACCCCGACTCCGCACCGCCTACCGCGATGGTGGCCGAAATTCGCGGTGAGTTTCTGTCTATTTTCCTATCGCCTACCGAAACGCTCAAACACTTCGTCAGTCTAGTCTCCGGAGGCGAGACCGCTGCCGCGAACATTGGCTGCCCAGTCGTGATCGAGGGTTACGGGCTGCCGACGGACCTGCGGCTGAAGTCGATGTGCGTCAAGCCAGGGCAAGTCGCGGCCGCTGCCAGCTTTGCTGCAGAACGCCAGCAGTTGGAAACCTTTTATGCACAGGCAGGAATGGCTCGGTTGTCGACGGAGTCGTTTGACGACAGCGGCGCACACGGCAGAACCGGCGGCAATAACCACATCACACTCGGCGACGTCACACCGCTACGGCGTCACCCCGATCTGTTGGTCTCGCTGCTGACCTGCTGGCAACGACACCCTTCGCGATCCTACCGGTTTGCGGGGCAATTCGTTGGCCCCATATCGCAGGCACCGCAAGTTGACGAGGTGCGCGCGTTTCGGCACCTGGTTGTCGATATCACCGGTAACATCCACCACGCCGAGTTTTGCATCGACAAGCTTCACAGCCACGATAACACCCACGGCAGGCTCAGTCTGTTAGAGTTACGTGGCTTTGCGATGCCGCTGTACCTGCAAATGGTGATAGTGCGTTGGCTGCTGGTTCGCTCGCTGGTGGCGTGGTTTTGGGAGGAACCGCTGCGCGCCTCAGTGATACGCCACGGCACCAATCTGCACGGCCGATACCTGTTTCCCCACTTCGTTAGCCATGATATGGCTGCCATAGCAACCAGCCTGCGTGAACACGGCCTCGCTTTCGAGACCAACTGGCTGTACCCGTTCATCGAATTCCGCTTACCGCGCCTCGGCACTTCTGTCTTCCACGGTGTGGAGATCGAGTTACGGAACGCGATCGAACCGTGGACTACGTTCGGCGAGAAGTCCACCGTAACCTCGCGCGGTGGCTGCACTTATCACGCCAGCCACACCGGGTCAAAAGCAATCAACACTGGCAGCACCCTCGAAGCCCAGGCACGCTGGAGCCGTCGCTTTGAAGCCACCGGTTTCATCCCAAGCAAAATTACTATGTCCTGCATCCGGAAAAGCAAGTCAGTATCTCCACCGACATCGACGCGCCTAGCATCCTCAACCTCAGACGCGTCCGCACCGTGATACGGTATA

Protein Sequence 

>ML2678_ML2678_protein
SAAMNIKVTLEHRTSYTFNRLVQVCPHVVRVHLAPHSRPPIEAHSLQIEPAGHFINCQQDTLGNGLTRLVLPNPMRRRSIGFGLITNLKMISPFDCYIENWAETWPATARSGPTFTYPEALAEDLKPYLRPVDEAGNRFVDNELVWAWIRNFPVPDGIRTINFINFLVAFNQAMNAEVSDIVCMEHGVPTTDFTLRTGISSCRDSAWLLVSILWQMRLTAWVVSSSATSYNCPPISRHSTSHRGLPPNSPTCTPGPKCPSPVRAKSGWTRSRGCSPTRSAYRWQPHHILRRQRRPTAQPTRAKRCWTSLTLSTQVQEDPHITLPYSDVAWHAICAIGQHGYQRLTVGGKPTVVLVNIHPNKGRKEWTMVAKSPSKRQPASDLTARLKAAWAPQGLIHFRQGQWYTGEPLPQWQITLYWRTKGQPLWTNDALLTDTWKAGPSERNKTTLEDSELAHKVLAQAADGLGLPLTQMRAAYKDTLRRLAAKVRIPSGAPVQLSDDRGPTTPDSAVNRVALLTRLEESVTLPDAYMLSLHSRDDNLSWVQATLQLHRGCIVLIEDASLAGLLLPLDSISWPRPHVSFYLDPMTFWRAWSAEPNTAAAVLENPDSAPPTAMVAEIRGEFLSIFLSPTETLKHFVSLVSGGETAAANIGCPVVIEGYGLPTDLRLKSMCVKPGQVAAAASFAAERQQLETFYAQAGMARLSTESFDDSGAHGRTGGNNHITLGDVTPLRRHPDLLVSLLTCWQRHPSRSYRFAGQFVGPISQAPQVDEVRAFRHLVVDITGNIHHAEFCIDKLHSHDNTHGRLSLLELRGFAMPLYLQMVIVRWLLVRSLVAWFWEEPLRASVIRHGTNLHGRYLFPHFVSHDMAAIATSLREHGLAFETNWLYPFIEFRLPRLGTSVFHGVEIELRNAIEPWTTFGEKSTVTSRGGCTYHASHTGSKAINTGSTLEAQARWSRRFEATGFIPSKITMSCIRKSKSVSPPTSTRLASSTSDASAP_YGI

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML2678 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

11 show intermediate predicted evidence for PPIs

53 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML2678

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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