ML2679
mL2679
Conserved hypothetical protein
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 3225410 – 3228091
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL2679_ML2679_dna
TATATGGTATCCACAGAAATGGCACTGAGCAACAGTGCATCGTCCTCGGCGCGTTTCAATCACTCTGACGCCGACCGACTGCTAGACGGGTACCGCGCCGCCCGCGCCCAGAAAGTTCTGTTCGACCTACACTCTGCCGGCACGGCCGGCCCGGGAATCGGCTACGATGAATTCGTCGACGACTCTGGCTACGTGCGACCTAGCTGGACCGAGTTGGCGGATGCGATCGGCGGCCGAGGTCGGGCCGGACTGCATCAATTGCGTTCGGTGATGCACCGACTAATCTACAACGATGGCATTACCTACACCGGGATCGACCCAGGAGCGCTCACCAATGACCACGGTGTGGTGCCGGGGCTCTGGCGGCTAGACTCGTTGCCGCTGTTGGTCTCTGCGACCGATTGGGAGGTATTAGAAGCCGGGCTGATTCAGCGCTCACGCCTACTCGATGCCGTACTCACAGACCTGTACGGGCCACGCCGCTTGCTAACCGACGGCGTGCTGCCGCCAGAACTGCTGTTCGGCCACCCTGGCTACGTGCGTACCGACCACGGCATCGAGGTTCCTGGGCATCACCAGCTCTTCATGCACGGCTGTGACCTCAGCCGGTTGCCAGACGGCGGGTTCCAGATCAACGCCGACTGGACGCAAGCGCCCTCGGGGGCCGGATATGCGCTGGCGGACCGACGTGTGGTCGCACAAGCACTTCCTGACCTCTACGAAACGATCGGGCCGCGACCGACTACACCGTTTGCTCAAGCACTGCGGTTGGCACTGATAGACGCAGCACCCGAGGTCGCTCAGGACCCAGTAGTTGTAGTGCTGAGCCCGGGAATTTACTCAGAAACCGCCTTCGATCAAGCGTATCTCGCAACTTTGCTGGGTTTCCAACTGGTAGAAAGCTCGGATTTAGTGGTGTGCGACGGCAAGGTGTGGATGCGTTCCTTGGGCACACTTAAACGCGTCGACGTGGTACTGCGCCGCGTCGACGCGGACTATATGGACCCCCTGGATCTTCGTGCCGATTCGCTGTTAGGCGTGGCCGGTTTGGTGGAGGCACAACATCGCGGAACGGTGACCGTTGTTAACACACTAGGCAGCGGCATTCTAGAAAGCGCAGGGCTACTGCGGTTCTTGCCCCAACTCTCCGAGCGTTTACTCGGAGAAACCCTATTGCTGCCCAGCGCACCCGTCTACTGGGCAGGAATCGACAGCGAACGCTTGCACCTGCTGACGAATTTGTCGTCGCTATTAATCAAATCCACCGTAGGCGGAAAAACCATTGTAGGACCATCACTTTCGTCCGGACAACTGACTGAAATGGCTGCTCGAATCGCAGCTAAGCCGTGGCAGTGGGTAGGCCAAGAACTGCCGCAATTCTCAACTGCACCCACAGATCATGATGGCGTGTTGTCACCGGCTAGCATCGGTATGCGAGTGTTCACGGTTGCCCAACGCAGCGGCTATGCACCGATGATCGGCGGTCTAGGGTATGCCCTGGCATCTGGAATTGATGCCTACTCTCTGAAAAAAGTTGCAGCAAAAGATATTTGGGTTCTTCCAACGGAGCGCGCACGCACCGAGGCGATAACCCATTCATTATTGGAGTCGCCGCCAATGACGGGAACAGGCACCTTGGGGGTGAGCTCGCCGCGGGTACTGTCCGACCTGTTTTGGATGGGGCGCTATGGTGAGCGCGCCGAAAACATGGCACGGTTGCTCATTGTCACCCGCGAGCACTACCACGATTCCCGGCACCGCCAGAACACGGAAGAAAACGCGTGCTTGCCGGTGCTGATAGCGGCGCTTGGTAAGATCACCGGGACCGACACCGGATCCGGTGGTCAGGCTGACGTGATAGCCGTTGCGCCCTCGACATTGTGGTCGCTCACTACCGACCGTAATCTGCCAGGGTCTCTGGTGCAGTCGGTGGACGGGCTAGTATTGGCAGCAAGAGCGGTGCGCGCCCAATTGTCCCGCGACACCTGGATGGTGCTCAGTGAAGTAGAGCGCGCTATGGTGCACGAGACCGAGCCGCCGGAGTCGTTGGTCGAGGGCGACGCCCTGCTGGCGTCGGTGCAAGCACGGACACTTGCTGGCATGCTGACACTGTCCGGATTAGCCGGTGAATCGATGGTGCGTGATATCGGCTGGACCATAATGGACATCGGAAAGCGCATCGAACGCGGGCTGGCGTTGACCGCCTTACTGCATGCCACGCTTACCGACGTCCGTAGCCCCGCGGCTGAGCACAGCATCATCGAGTCAATCCTGGTAATTTGTGAGTCATCGGTCATCTACCAGCGCCGCACGGTAAGCACGATCGATGTTGCCGTTGTCGCTGAGCTCATGCTGTTCGACGCGACGAACCCGCGGTCACTGGTGTATCAACTGGATCGGTTACGCGTCGATCTCGCTGACCTTCCGGGCTCGTCGAGGTCATCACTCCCGGAGCGGATGGTGGCCGAGATGAGCACCCGGCTGCGCCGGTCCGCTCCCGCTCAGCTGAAAGAGGTCAGTGCCGACGGGCGCCGCTATGTGCTGGCTGAGCTACTCGCCGCGGTCGACACCGCGTTGCGTGACTTGGCCGACGCGATCACCGCAACCCAATTGGCGGTGCCCTGCGGCATGCAACCACTATGGGGGCCTGACAATCGACAAACCATGTCGTAACCAGCATGC

Protein Sequence 

>ML2679_ML2679_protein
YMVSTEMALSNSASSSARFNHSDADRLLDGYRAARAQKVLFDLHSAGTAGPGIGYDEFVDDSGYVRPSWTELADAIGGRGRAGLHQLRSVMHRLIYNDGITYTGIDPGALTNDHGVVPGLWRLDSLPLLVSATDWEVLEAGLIQRSRLLDAVLTDLYGPRRLLTDGVLPPELLFGHPGYVRTDHGIEVPGHHQLFMHGCDLSRLPDGGFQINADWTQAPSGAGYALADRRVVAQALPDLYETIGPRPTTPFAQALRLALIDAAPEVAQDPVVVVLSPGIYSETAFDQAYLATLLGFQLVESSDLVVCDGKVWMRSLGTLKRVDVVLRRVDADYMDPLDLRADSLLGVAGLVEAQHRGTVTVVNTLGSGILESAGLLRFLPQLSERLLGETLLLPSAPVYWAGIDSERLHLLTNLSSLLIKSTVGGKTIVGPSLSSGQLTEMAARIAAKPWQWVGQELPQFSTAPTDHDGVLSPASIGMRVFTVAQRSGYAPMIGGLGYALASGIDAYSLKKVAAKDIWVLPTERARTEAITHSLLESPPMTGTGTLGVSSPRVLSDLFWMGRYGERAENMARLLIVTREHYHDSRHRQNTEENACLPVLIAALGKITGTDTGSGGQADVIAVAPSTLWSLTTDRNLPGSLVQSVDGLVLAARAVRAQLSRDTWMVLSEVERAMVHETEPPESLVEGDALLASVQARTLAGMLTLSGLAGESMVRDIGWTIMDIGKRIERGLALTALLHATLTDVRSPAAEHSIIESILVICESSVIYQRRTVSTIDVAVVAELMLFDATNPRSLVYQLDRLRVDLADLPGSSRSSLPERMVAEMSTRLRRSAPAQLKEVSADGRRYVLAELLAAVDTALRDLADAITATQLAVPCGMQPLWGPDNRQTMS_PAC

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML2679 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

2 proteins show strong predicted evidence for PPIs

9 show intermediate predicted evidence for PPIs

73 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML2679

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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