rv2512c
rv2512c
transposase
M. tuberculosis · H37Rv
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [U19] [TnSeq DB] [SeqHub] [evo-mtb]
H37Rv Coordinates: 2828566 – 2829813
Vulnerability Index (VI):
M. smegmatis homologs MSMEG4154
M. abscessus homologs
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon TSS Legend ? Ju, 2024 (4) Cortes, 2013 (5) Shell, 2015 (3) (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 (5) PMID: 24268774 Rv2510c orn RVBD2512A Rv2512c Rv2513 Rv2514c Rv2515c Rv2516c tRNA-His
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>rv2512c_Rv2512c_dna
GTGGCCATATATCTGGTTGCTATCGATGATGGACAGCGTTGCACAGTTTCGTTTGCCGCAGAGGCAGCCGTGCCCGGTTGACTGATGATAGCGGCCGAGCTTTTCGAACTCTCTTAACACGGCATCGTGAGACCTAAACGCAGCCAGCATCTTTGCCTTGTAGTCATCGGCGCGGAGTTACGTCCAGGGGTGTGGTGTACGGGCAGGTAAGGCCGGTGGGCGTGTCGTAGCCCAGTAGTGGGCGGTCATCGCGTGATCCTTCGAAACGACCAGCAAAAGTCAATCGAAGGAAATGACGCAATGACCTCTTCTCATCTTATCGACACCGAGCAGCTTCTGGCTGACCAACTCGCACAGGCGAGCCCGGATCTGCTGCGCGGGCTGCTCTCGACGTTCATCGCCGCCTTGATGGGGGCTGAAGCCGACGCCCTGTGCGGGGCGGGCTACCGCGAACGCAGCGATGAGCGGTCCAATCAGCGCAACGGCTACCGCCACCGTGATTTCGACACCCGTGCCGCAACCATCGACGTCGCGATCCCCAAGCTGCGCCAGGGCAGCTATTTCCCGGACTGGCTGCTGCAGCGCCGCAAGCGAGCTGAACGCGCACTGACCAGCGTGGTGGCGACCTGCTACCTGCTGGGAGTATCCACTCGCCGGATGGAGCGCCTGGTCGAAACACTTGGTGTGACAAAGCTTTCCAAGTCGCAAGTGTCGATCATGGCCAAAGAGCTCGACGAAGCCGTAGAGGCGTTTCGGACCCGCCCGCTCGATGCCGGCCCGTATACCTTCCTCGCCGCCGACGCCCTGGTGCTCAAGGTGCGCGAGGCAGGCCGCGTCGTCGGAGTGCACACCTTGATCGCCACCGGCGTCAACGCCGAGGGCTACCGAGAGATCCTGGGCATCCAGGTCACCTCCGCCGAGGACGGGGCCGGCTGGCTGGCGTTCTTCCGCGACCTGGTCGCCCGCGGCCTGTCCGGGGTCGCGCTGGTCACCAGCGACGCCCACGCCGGCCTGGTGGCCGCGATCGGCGCCACCCTGCCCGCAGCGGCCTGGCAGCGCTGCAGAACCCACTACGCAGCCAATCTGATGGCAGCCACCCCGAAGCCCTCCTGGCCGTGGGTGCGCACCCTGCTGCACTCCATCTACGACCAGCCCGACGCCGAATCAGTTGTTGCCCAATATGATCGGGTACTCGACGCTCTGACCGACAAACTCCCCGCGGTGGCCGAGCACCTCGACACCGCCCGCACCGACCTGCTGGCGTTCACCGCCTTCCCCAAGCAGATCTGGCGCCAAATCTGGTCCAACAACCCCCAGGAACGCCTCAACCGAGAGGTACGACGCCGAACCGACGTCGTGGGCATCTTCCCCGACCGCGCCTCGATCATCCGCCTCGTCGGAGCCGTCCTCGCCGAACAACACGACGAATGGATCGAAGGACGGCGCTACCTGGGCCTCGAGGTCCTCACCCGAGCCCGAGCAGCACTGACCAGCACCGAAGAACCCGCCAAGCAGCAAACCACCAACACCCCAGCACTGACCACCTAG

Protein Sequence 

>Rv2512c_Rv2512c_protein
MTSSHLIDTEQLLADQLAQASPDLLRGLLSTFIAALMGAEADALCGAGYRERSDERSNQRNGYRHRDFDTRAATIDVAIPKLRQGSYFPDWLLQRRKRAERALTSVVATCYLLGVSTRRMERLVETLGVTKLSKSQVSIMAKELDEAVEAFRTRPLDAGPYTFLAADALVLKVREAGRVVGVHTLIATGVNAEGYREILGIQVTSAEDGAGWLAFFRDLVARGLSGVALVTSDAHAGLVAAIGATLPAAAWQRCRTHYAANLMAATPKPSWPWVRTLLHSIYDQPDAESVVAQYDRVLDALTDKLPAVAEHLDTARTDLLAFTAFPKQIWRQIWSNNPQERLNREVRRRTDVVGIFPDRASIIRLVGAVLAEQHDEWIEGRRYLGLEVLTRARAALTSTEEPAKQQTTNTPALTT

Essentiality:

Call Condition Type Source Notes
Non Essential in vitro TnSeq [DeJesus et al. (2017)]
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]

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