rv1546
rv1546
hypothetical protein
M. tuberculosis · H37Rv
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H37Rv Coordinates: 1747201 – 1747632
Vulnerability Index (VI):
M. smegmatis homologs MSMEG5634, MSMEG3418
M. abscessus homologs MAB0966
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon TSS Legend ? Ju, 2024 (4) Cortes, 2013 (5) Shell, 2015 (3) (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 (5) PMID: 24268774 lprI glbN Rv1543 Rv1544 Rv1545 Rv1546 dnaE
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>rv1546_Rv1546_dna
GATGTGAGGGGCGTTCCGGCCTGGTGCCGAACGGAGTGCTGGGCCTGGGCAATCCCAGCCGGCTAGCCGCGTTGTATGGGTTGCAGCTGGCGCACGAGTCGCAGTGCTGCCAGATGCACAATTTGCCCTCTGCAGCGCGACAAGTCACTGTTGCGTGTCGCGAGGAGGTGGGCATAACGACCATCCTTGCCGGCAGAGACGAATGCGGCGTGTGTGACAAGACAGCTGGGTTGGATGGCGCCGCTCCTTAGCGGGCCATAGCGCACGGCCCGCTTCGTCGCCGGCGCTAGTCTCATGCGATGGCCTCTGTTGAGCTGTCCGCTGACGTCCCCATCAGCCCGCAGGACACGTGGGACCACGTTTCGGAGCTGTCAGAGTTGGGGGAGTGGCTCGTCATCCATGAGGGGTGGCGCAGCGAGTTGCCTGATCAACTGGGCGAAGGCGTCCAGATCGTGGGTGTCGCGCGGGCCATGGGCATGCGCAACCGGGTTACGTGGCGGGTGACCAAGTGGGACCCGCCACATGAGGTCGCGATGACAGGATCCGGGAAGGGTGGAACAAAGTACGGAGTCACCCTCACCGTGCGACCCACAAAAGGCGGGTCGGCGCTGGGGCTGCGTCTCGAGCTGGGCGGGCGTGCGCTGTTCGGCCCGCTGGGTTCGGCGGCGGCTCGCGCCGTCAAGGGCGACGTCGAGAAGTCGCTTAAGCAGTTCGCCGAGCTATACGGCTAG

Protein Sequence 

>Rv1546_Rv1546_protein
MASVELSADVPISPQDTWDHVSELSELGEWLVIHEGWRSELPDQLGEGVQIVGVARAMGMRNRVTWRVTKWDPPHEVAMTGSGKGGTKYGVTLTVRPTKGGSALGLRLELGGRALFGPLGSAAARAVKGDVEKSLKQFAELYG

Essentiality:

Call Condition Type Source Notes
Non Essential in vitro TnSeq [DeJesus et al. (2017)]
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]

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