rv3115
rv3115
transposase
M. tuberculosis · H37Rv
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [U19] [TnSeq DB] [SeqHub] [evo-mtb]
H37Rv Coordinates: 3481448 – 3482695
Vulnerability Index (VI):
M. smegmatis homologs MSMEG4154
M. abscessus homologs
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon TSS Legend ? Ju, 2024 (4) Cortes, 2013 (5) Shell, 2015 (3) (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 (5) PMID: 24268774 moaA1 moaB1 moaC moaD1 Rv3113 Rv3114 Rv3115 moeB2 cysA3 sseC1 moaE1 Rv3120
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>rv3115_Rv3115_dna
TCGGATGTGGTGGCGGCCTCCACTCGTCCCACGCGTCCATCGGTGTATAGCGGTTTCCTCAGCCACAAGACGGACTTGTTGTACCGGAACTCCGAAAACCGACGAGCAATGAACCCCTGGACCGATCCATCGCATTGACTCGGCTTGCCGACTACCTCACTGACCCAGGAGGAGAGTTACGTCCAGGGGTGTGGTGTACGGGCAGGTAAGGCCGGTGGGCGTGTCGTAGCCCAGTAGTGGGCGGTCATCGCGTGATCCTTCGAAACGACCAGCAAAAGTCAATCGAAGGAAATGACGCAATGACCTCTTCTCATCTTATCGACGCCGAGCAGCTTCTGGCTGACCAACTCGCACAGGCGAGCCCGGATCTGCTGCGCGGGCTGCTCTCGACGTTCATCGCCGCCTTGATGGGGGCTGAAGCCGACGCCCTGTGCGGGGCGGGCTACCGCGAACGCAGCGATGAGCGGTCCAATCAGCGCAACGGCTACCGCCACCGTGATTTCGACACCCGTGCCGCAACCATCGACGTCGCGATCCCCAAGCTGCGCCAGGGCAGCTATTTCCCGGACTGGCTGCTGCAGCGCCGCAAGCGAGCTGAACGCGCACTGACCAGCGTGGTGGCGACCTGCTACCTGCTGGGAGTATCCACTCGCCGGATGGAGCGCCTGGTCGAAACACTTGGTGTGACAAAGCTTTCCAAGTCGCAAGTGTCGATCATGGCCAAAGAGCTCGACGAAGCCGTAGAGGCGTTTCGGACCCGCCCGCTCGATGCCGGCCCGTATACCTTCCTCGCCGCCGACGCCCTGGTGCTCAAGGTGCGCGAGGCAGGCCGCGTCGTCGGGGTGCACACCTTGATCGCCACCGGCGTCAACGCCGAGGGCTACCGAGAGATCCTGGGCATCCAGGTCACCTCCGCCGAGGACGGGGCCGGCTGGCTGGCGTTCTTCCGCGACCTGGTCGCCCGCGGCCTGTCCGGGGTCGCGCTGGTCACCAGCGACGCCCACGCCGGCCTGGTGGCCGCGATCGGCGCCACCCTGCCCGCAGCGGCCTGGCAGCGCTGCAGAACCCACTACGCAGCCAATCTGATGGCAGCCACCCCGAAGCCCTCCTGGCCGTGGGTGCGCACCCTGCTGCACTCCATCTACGACCAGCCCGACGCCGAATCAGTTGTTGCCCAATATGATCGGGTACTCGACGCTCTGACCGACAAACTCCCCGCGGTGGCCGAGCACCTCGACACCGCCCGCACCGACCTGCTGGCGTTCACCGCCTTCCCCAAGCAGATCTGGCGCCAAATCTGGTCCAACAACCCCCAGGAACGCCTCAACCGAGAGGTACGACGCCGAACCGACGTCGTGGGCATCTTCCCCGACCGCGCCTCGATCATCCGCCTCGTCGGAGCCGTCCTCGCCGAACAACACGACGAATGGATCGAAGGACGGCGCTACCTGGGCCTCGAGGTCCTCACCCGAGCCCGAGCAGCACTGACCAGCACCGAAGAACCCGCCAAGCAGCAAACCACCAACACCCCAGCACTGACCACCTAG

Protein Sequence 

>Rv3115_Rv3115_protein
MTSSHLIDAEQLLADQLAQASPDLLRGLLSTFIAALMGAEADALCGAGYRERSDERSNQRNGYRHRDFDTRAATIDVAIPKLRQGSYFPDWLLQRRKRAERALTSVVATCYLLGVSTRRMERLVETLGVTKLSKSQVSIMAKELDEAVEAFRTRPLDAGPYTFLAADALVLKVREAGRVVGVHTLIATGVNAEGYREILGIQVTSAEDGAGWLAFFRDLVARGLSGVALVTSDAHAGLVAAIGATLPAAAWQRCRTHYAANLMAATPKPSWPWVRTLLHSIYDQPDAESVVAQYDRVLDALTDKLPAVAEHLDTARTDLLAFTAFPKQIWRQIWSNNPQERLNREVRRRTDVVGIFPDRASIIRLVGAVLAEQHDEWIEGRRYLGLEVLTRARAALTSTEEPAKQQTTNTPALTT

Essentiality:

Call Condition Type Source Notes
Non Essential in vitro TnSeq [DeJesus et al. (2017)]
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]

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