rv3440c
rv3440c
hypothetical protein
M. tuberculosis · H37Rv
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H37Rv Coordinates: 3859845 – 3860156
Vulnerability Index (VI):
M. smegmatis homologs MSMEG1560
M. abscessus homologs MAB3747c
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon TSS Legend ? Ju, 2024 (4) Cortes, 2013 (5) Shell, 2015 (3) (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 (5) PMID: 24268774 glmS Rv3437 Rv3438 Rv3439c Rv3440c mrsA rpsI rplM esxT esxU
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>rv3440c_Rv3440c_dna
GGCGTCGGCGATGCGGACGTTGCCGCAGGTGCTGATCAACGTCGAGGTTGTCGACAAGGCCACCGCCGCCGCGGCGCCCTCGGTCCGAACGGCGGTCGAGCAGGCCGCGGCCGAGCTGGGTGACACGGGTCGAATCCTCTTGCGCCCGTCCGGAACTGAGCCGATGATTCGGGTGATGGTGGAGGCAGCCGACGAGGGCGTCGCCCAGCGGCTGGCGGCCACGGTCGCCGACGCGGTGAGCACCGCGCGCTGAACCGGAAATGCTGGAACCCCGACGCGGCGCGGGGCGTCCGAATAGGCATGAGACCCGATAGCGTAAACAGCGCCGGCATAGACATAGCAGCGGTATACGCGGTTGCCGACCGGTTCAGCGCCGCCGCCGAGCTCATCGATGACGCCATCGGCAATCACCTGACGAGGCTGGCTTTTGGCGGAGCCTGCGCGGGCCGGGGGCACGCCTCGCGTGGCGATGCGTTGCGCTGCAGGCTAGACCGGTTGGCCGGCGAGTTGTCAGTGTGGTCCCGGGCGGCTGTGCAGATCGCGTTTGCGTTGCGGGCGGGCGCCAACCGCTACGCCGAGGCCGACCTGTGCGCGGCGGCGCGGATCGGGTGA

Protein Sequence 

>Rv3440c_Rv3440c_protein
MRPDSVNSAGIDIAAVYAVADRFSAAAELIDDAIGNHLTRLAFGGACAGRGHASRGDALRCRLDRLAGELSVWSRAAVQIAFALRAGANRYAEADLCAAARIG

Essentiality:

Call Condition Type Source Notes
Growth Advantage in vitro TnSeq [DeJesus et al. (2017)]
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]

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