MSMEG0430
ms0430
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 505025 – 506392
Vulnerability Index (VI):
M. tuberculosis homologs Rv3349c, Rv0741, Rv3798, Rv1313c
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 nirB MSMEG0428 MSMEG0429 MSMEG0430 MSMEG0431 MSMEG0432 MSMEG0433
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms0430_MSMEG0430_dna
AACGATCGTGGACACGATAGCTGAGTTCAAGTCGGCAACCCGCAACCGCCCTGTTCCGGACCCTGGAACCGGCGCATCCGTCAATTAATTGCCTGAGTAAATACCAGAACAACCGGTGTTTGAGACGCCGTATTCCTGGGAACCCCGGCAGGGCGAACGTTGGAAGCCCGTGATGTCCCTCATGACTGGCTAACTAGATTTGTTCGCTGGCGGTGTTTATCGGCTCTTCGCACTTGATAGGGGTCTGGTGTTGTCCGACGTTGTGTCGTGTCGGTGATTGATTAGGGGTCCGCGCCCCTGTGAGCTGGGTGTTCTTCAGGCATCCAGGACAAGGAACGCGGACCATGGTTGACGGTAGTTCACTGCTGCTCGATCTCGACGGTGTGGTCGTCGAATCGGTGCAGCGCCTCGAGGACGGCACCCGGTTGGTGCAGGTGCTCACCGCCCCCCAGTGGGTCGGGATCTGCCCCGAATGCGGGGAACGCTCCACCAGGTCGAAAGGCTGGGTACAGACCGGACCCCGCGACGTTGTGGTGGGTCCGGACCGCCCGATACTGCGCTGGCGTAAGCGAAAGTGGTTGTGCCCCAGCACGGTCTGTACGCGCAAGGTGTTCACCGAGTCGGTGCCCGGAATCCCGGCGCGGGCGCGGGTAACACCGCGGGCCAAGGCGACGATGGCCACTGCGGTGCTCGACGAGGACCGTTCGGTGGCCGCGGTGGCCGGGCAGTACCGCTGCGGCTGGCACACCGTGCACGACGAAGTCATCGCCACCGCCGAGGACGCCCTGGCCGGCGAGCTGGCGCCGGTGGCGGTGCTCGGCATCGACGAGACCCGACGCGGTAAGGCCAAATGGGAACACAACCCGGTACTCGGGCGGCGGGTATGGGTGGATCGCTGGGACACCGGACTGGTCGACATCACCGGCGATCAAGGCCTCCTTGGCCAGGTCAACGGCCGCACCTCGGCGGCAGTGATCGACTGGCTCGCTGGCCAGGACCCTGACTGGCGGGCCGCAATCACCCACGTAGCCATCGACCTGTCCCCGGCCTATGCCCGGGTGGCTCGCGAAGCACTGCCGCACGCGATCCTGATCGCCGACCGGTTCCACCTGGTCAAGAAAGCCAACGACATGGTTGATGCGGTGCGCCGCCGGGTCACCTGGACCCAACGGGGCCGGCGCGGCCGCAAGGCCGATGTCGAGTGGATCAACCGCCGCCGCCTGCTGCGCGGCTCCGAGCGGCTCACCGCAGACCAACGCGCCACGTTGTTCGCCAAGCTGCTCTCCGCCGACCCCAACCAGGACATCGCCGCGGCCTGGATCGCCAAAGAACTGCTGCGCGACCTGCTTTCCTGCGCCGACCGCGGCGGGTTGCGCTACGAGATCACGACCGCCCTGGACCGGTTCTACCGTTTCTGCGCGGCCTGCACAGTGCCCGAAGTGATCCGACTGGCCCGCACCATCGAGACCTGGCAGGCCCCCATCATCGCCGCCCTGCAGACCGGCCTGTCCAACGCCCGCACCGAAGGCTACAACCGCATCGTCAAACACGTCGGGCGCATCGCCTTCGGCTTCCGCAATCCTGAGAACCAACGCCGCCGAGTACGGTGGGCCTGCACTCGCCGATCACGACGAGTCACACCCAGCCGGCACCAACGCCACTGCTAA

Protein Sequence 

>Ms0430_MSMEG0430_protein
VSWVFFRHPGQGTRTMVDGSSLLLDLDGVVVESVQRLEDGTRLVQVLTAPQWVGICPECGERSTRSKGWVQTGPRDVVVGPDRPILRWRKRKWLCPSTVCTRKVFTESVPGIPARARVTPRAKATMATAVLDEDRSVAAVAGQYRCGWHTVHDEVIATAEDALAGELAPVAVLGIDETRRGKAKWEHNPVLGRRVWVDRWDTGLVDITGDQGLLGQVNGRTSAAVIDWLAGQDPDWRAAITHVAIDLSPAYARVAREALPHAILIADRFHLVKKANDMVDAVRRRVTWTQRGRRGRKADVEWINRRRLLRGSERLTADQRATLFAKLLSADPNQDIAAAWIAKELLRDLLSCADRGGLRYEITTALDRFYRFCAACTVPEVIRLARTIETWQAPIIAALQTGLSNARTEGYNRIVKHVGRIAFGFRNPENQRRRVRWACTRRSRRVTPSRHQRHC

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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