MSMEG0725
ms0725
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 812164 – 813117
Vulnerability Index (VI):
M. tuberculosis homologs Rv3475, Rv3380c, Rv3326, Rv3187, Rv3185, [+ 13 remaining orthologs]
M. abscessus homologs MAB2086c, MAB2088
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG0720 MSMEG0722 MSMEG0723 MSMEG0724 MSMEG0725 MSMEG0726 MSMEG0727 MSMEG0728 MSMEG0729 MSMEG0730
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms0725_MSMEG0725_dna
GACGAGCTGAAGGTGCGGGCGGTGCAGATGGTGGCCGATCTGCGCAGCGAGACAGTTTCGGAGTGGGAGGCGATGGGCCGGGTTGCTGACCTGCTGGGCGTCGGTACTGCCGAAACGGTGCGCAAATGGGTCCGCCAGGCTGAGATCGACGCCGGCTCTCGGGCGGGGCAGACCAGCGAGGAATCCGAGGTCCTGCGCAAGCTGCGCCGGGAGAATGCCGAACTCAAGCGGGCCAACGCGATCTTGAAGGCGGCCTCGGTTTTCTTCGCCGCCGAGCTCGACCGGCCCTCTCAGTAGTCGTGGAGTTCATCAGCGCCCACCAGCACATGCGGGTGGGCGTTGATGGTCTCAAGTGGGGTGTCGAGTCGATGTGCGCTGTGCTTTCCGAGTACGGCGTCACGATCGCCCCGTCGACGTATTACGCCCACCGCGCCCGTCAGGGCCCCTCGAAAGCCGACTGGGCCGATGCGCAGGTGATCGATGCGATCTGGCAGCTTCGCCAATCGCAGAGTCTGTACCGAGTCCTGGGCGCTCGTAAGACATGGATTGTATTGCGCACCAATGGTATCGACGTATCGCGCTGTGTCGTGGAACGGGTCATGCGGGAGATGGGTTGGCGGGGTGCGTGCAAGCGCCGGCGGGTGCGCACCACCGTCGCCGATCCGGCAGCGACGCGAGCCCCGGATCGGGTCCGGCGTAATTTCGTCGCCGGTGCGCCTGACCGATTGTGGGTGGCCGATTTCACCTACTGCCGGACTCGTGCCGGCTGGGCCTACACGGCGTTCGTCACCGATGTCTATGCCCGCAAGATCGTGGGTTGGAAGGTGGCTACCGAGATGACCCAGAAGCTGGTGACCGATGCGATCGACCACGCTATCGACACCAGAAAGCGTTCGGGTGCAGCATCTTTGGATTCACTTATCCACCACAGCGACGCGGGCTCGCAATACACCGCGGTCGCGTTCACCGAACGTCTGGCCGCTGAGGGGATCCTGCCTTCAGTCGGATCCGTCGGGGATAGTTTCGATAATGCTCTGGCCGAATCGGTGAACAGCAGCTACAAGACCGAACTCATCGACCGCCAGCCGCTCTATCCCGGTGCCACCGAACTGGCGCTGGGGACCGCCGAATGGGTGGCCTTCTACAACCGTCAGCGACCCAACGGCTACTGCCAGGACCTGACCCCCGATCGGGCCGAAGCGCTCTACTACCATCGCCAACGGCACCCTCATGCCGAGGAGGCACTCAGATAA

Protein Sequence 

>Ms0725_MSMEG0725_protein
VEFISAHQHMRVGVDGLKWGVESMCAVLSEYGVTIAPSTYYAHRARQGPSKADWADAQVIDAIWQLRQSQSLYRVLGARKTWIVLRTNGIDVSRCVVERVMREMGWRGACKRRRVRTTVADPAATRAPDRVRRNFVAGAPDRLWVADFTYCRTRAGWAYTAFVTDVYARKIVGWKVATEMTQKLVTDAIDHAIDTRKRSGAASLDSLIHHSDAGSQYTAVAFTERLAAEGILPSVGSVGDSFDNALAESVNSSYKTELIDRQPLYPGATELALGTAEWVAFYNRQRPNGYCQDLTPDRAEALYYHRQRHPHAEEALR

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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