MSMEG1239
ms1239
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1310225 – 1311592
Vulnerability Index (VI):
M. tuberculosis homologs Rv3349c, Rv0741, Rv3798, Rv1313c
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG1236 MSMEG1237 MSMEG1238 MSMEG1239 MSMEG1240 MSMEG1241 iscS
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1239_MSMEG1239_dna
AGGCATTTTCAGGGCCGTCCTGCCAGGACCATACTTCCACCCGCTTACATTGCGAGATCGAAGCACTCGGCAATCCCATTCCGAAACGGCCAATTCCTTCTCGACTGTCAAGGTGGGTACCGTTTCCAAACTGCAAAGCCATTCTCAGTACTGCAGCGTTCATACCAGTTCCGTTATCCAGAACGGCGACCTGCGAAATTCTGCGCCGACTACGGGTTTGAAGGCTCTTCGCACTTGATAGGGGTCTGGTGTTGTCCGACGTTGTGTCGTGTCGGTGATTGATTAGGGGTCCGCGCCCCTGTGAGCTGGGTGTTCTTCAGGCATCCAGGACAAGGAACGCGGACCATGGTTGACGGTAGTTCACTGCTGCTCGATCTCGACGGTGTGGTCGTCGAATCGGTGCAGCGCCTCGAGGACGGCACCCGGTTGGTGCAGGTGCTCACCGCCCCCCAGTGGGTCGGGATCTGCCCCGAATGCGGGGAACGCTCCACCAGGTCGAAAGGCTGGGTACAGACCGGACCCCGCGACGTTGTGGTGGGTCCGGACCGCCCGATACTGCGCTGGCGTAAGCGAAAGTGGTTGTGCCCCAGCACGGTCTGTACGCGCAAGGTGTTCACCGAGTCGGTGCCCGGAATCCCGGCGCGGGCGCGGGTAACACCGCGGGCCAAGGCGACGATGGCCACTGCGGTGCTCGACGAGGACCGTTCGGTGGCCGCGGTGGCCGGGCAGTACCGCTGCGGCTGGCACACCGTGCACGACGAAGTCATCGCCACCGCCGAGGACGCCCTGGCCGGCGAGCTGGCGCCGGTGGCGGTGCTCGGCATCGACGAGACCCGACGCGGTAAGGCCAAATGGGAACACAACCCGGTACTCGGGCGGCGGGTATGGGTGGATCGCTGGGACACCGGACTGGTCGACATCACCGGCGATCAAGGCCTCCTTGGCCAGGTCAACGGCCGCACCTCGGCGGCAGTGATCGACTGGCTCGCTGGCCAGGACCCTGACTGGCGGGCCGCAATCACCCACGTAGCCATCGACCTGTCCCCGGCCTATGCCCGGGTGGCTCGCGAAGCACTGCCGCACGCGATCCTGATCGCCGACCGGTTCCACCTGGTCAAGAAAGCCAACGACATGGTTGATGCGGTGCGCCGCCGGGTCACCTGGACCCAACGGGGCCGGCGCGGCCGCAAGGCCGATGTCGAGTGGATCAACCGCCGCCGCCTGCTGCGCGGCTCCGAGCGGCTCACCGCAGACCAACGCGCCACGTTGTTCGCCAAGCTGCTCTCCGCCGACCCCAACCAGGACATCGCCGCGGCCTGGATCGCCAAAGAACTGCTGCGCGACCTGCTTTCCTGCGCCGACCGCGGCGGGTTGCGCTACGAGATCACGACCGCCCTGGACCGGTTCTACCGTTTCTGCGCGGCCTGCACAGTGCCCGAAGTGATCCGACTGGCCCGCACCATCGAGACCTGGCAGGCCCCCATCATCGCCGCCCTGCAGACCGGCCTGTCCAACGCCCGCACCGAAGGCTACAACCGCATCGTCAAACACGTCGGGCGCATCGCCTTCGGCTTCCGCAATCCTGAGAACCAACGCCGCCGAGTACGGTGGGCCTGCACTCGCCGATCACGACGAGTCACACCCAGCCGGCACCAACGCCACTGCTAA

Protein Sequence 

>Ms1239_MSMEG1239_protein
VSWVFFRHPGQGTRTMVDGSSLLLDLDGVVVESVQRLEDGTRLVQVLTAPQWVGICPECGERSTRSKGWVQTGPRDVVVGPDRPILRWRKRKWLCPSTVCTRKVFTESVPGIPARARVTPRAKATMATAVLDEDRSVAAVAGQYRCGWHTVHDEVIATAEDALAGELAPVAVLGIDETRRGKAKWEHNPVLGRRVWVDRWDTGLVDITGDQGLLGQVNGRTSAAVIDWLAGQDPDWRAAITHVAIDLSPAYARVAREALPHAILIADRFHLVKKANDMVDAVRRRVTWTQRGRRGRKADVEWINRRRLLRGSERLTADQRATLFAKLLSADPNQDIAAAWIAKELLRDLLSCADRGGLRYEITTALDRFYRFCAACTVPEVIRLARTIETWQAPIIAALQTGLSNARTEGYNRIVKHVGRIAFGFRNPENQRRRVRWACTRRSRRVTPSRHQRHC

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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