MSMEG2328
ms2328
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 2409628 – 2410335
Vulnerability Index (VI):
M. tuberculosis homologs echA17, echA8, echA14, echA11, echA1, [+ 8 remaining orthologs]
M. abscessus homologs MAB3382c, MAB0903, MAB1185c, MAB0905, MAB2737c, [+ 12 remaining orthologs]
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG2323 MSMEG2324 MSMEG2325 MSMEG2326 MSMEG2327 MSMEG2328 MSMEG2329 MSMEG2330 MSMEG2331 MSMEG2332
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms2328_MSMEG2328_dna
GTCGCGGCCCTCCCGGAGGGCCAGCGCGCCGACGGCGAGAACACCGAGACCGACCGGGCGTTCTGGTGCACACCGAAAGCCGGGCTCGACGACTTCGAGGCGGGGAACACCTTCCTGCTGCCGCCGACCTGGACGCAGCTGGACTCCCTCGACGGCCGCACGGTGGCCGAGGTGCTGGCGGTCGAACGCAAGATCGTGACGATCGAGCCCAGCCTGTCGACCGAGGGCAACAACTGGGAGATCGAATACTTCGACAGCGGGCGCTACAACGCTGCACGCAAGCATCGGTCGCCCGGGCAATGAACGAGTTCATCAAGATCGTCCTCGGTTCCGCGCCCGAGCAGACGGGCGTGGCCACGTTGCTGTTGTCGCGGCCCCCGACGAACGCGTTGACCCGCCAGATGTACCGCGAGATCTCCATCGCCGCGAACGAGCTCGCCCAGCGCGCCGACGTGTCGTCGGTCATCGTCTACGGCGGCCACGAGATCTTCTGCGCGGGCGACGACATCCCCGAACTGCGCACCCTCGACGCCGAAGAGACCGCGGCGGCCGACCACGCGCTGCAGCGCTGCATCGAGGCCGTTGCCGCCATCCCCAAACCCACGGTCGCGGCCGTCACCGGGTACGCGCTCGGCAGCGGGATGAACCTGGCGCTGGCCGCGGACTGGCGGGTGAGCGGCGACAACGCCAAGTTCGGCGCCACCGAGATCCTGGCGGGGCTGGCACCGCGCGGCGGCGGCGGGGTACGCCTGGCGGACGCCATCGGGACCAGCAAGGCCAAGGAGCTCGTGTTCAGCGGCCGGTTCGTCGGCGCCGAGGAAGCGCTCGAGATCGGCCTGGTCGACGAGATGGTGGCACCCGACCACGTCTACGAGGCCGCGCTCGCGTGGGCCCGCCGGTTCTCCGACCATCCGGTCGACGTGCTGGCCGCCGCGAAAGCCTCCCTCAACGGGCCGGTCAACTGGCGGGGCCCCCGCCCGACCGATCGGATGGTGGACCGGCCCTGA

Protein Sequence 

>Ms2328_MSMEG2328_protein
MNEFIKIVLGSAPEQTGVATLLLSRPPTNALTRQMYREISIAANELAQRADVSSVIVYGGHEIFCAGDDIPELRTLDAEETAAADHALQRCIEAVAAIPKPTVAAVTGYALGSGMNLALAADWRVSGDNAKFGATEILAGLAPRGGGGVRLADAIGTSKAKELVFSGRFVGAEEALEIGLVDEMVAPDHVYEAALAWARRFSDHPVDVLAAAKASLNGPVNWRGPRPTDRMVDRP

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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