MSMEG2329
ms2329
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 2410370 – 2411350
Vulnerability Index (VI):
M. tuberculosis homologs Rv3038c, Rv2952, Rv1523
M. abscessus homologs MAB3381c, MAB4018, MAB4799c, MAB0868c, MAB2257, [+ 6 remaining orthologs]
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG2325 MSMEG2326 MSMEG2327 MSMEG2328 MSMEG2329 MSMEG2330 MSMEG2331 MSMEG2332
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms2329_MSMEG2329_dna
GGTACGCCTGGCGGACGCCATCGGGACCAGCAAGGCCAAGGAGCTCGTGTTCAGCGGCCGGTTCGTCGGCGCCGAGGAAGCGCTCGAGATCGGCCTGGTCGACGAGATGGTGGCACCCGACCACGTCTACGAGGCCGCGCTCGCGTGGGCCCGCCGGTTCTCCGACCATCCGGTCGACGTGCTGGCCGCCGCGAAAGCCTCCCTCAACGGGCCGGTCAACTGGCGGGGCCCCCGCCCGACCGATCGGATGGTGGACCGGCCCTGACCGGGACACCGGGGCGGCCATTAGGCTGCCCTGCATGACGGAAATCAGGGACGCCGCCGACCCGGCTCCGAACCCGCACGCCACGGCCGAAGAGGTCGAAGCCGCGATGCACGACAGCAAGCTGGCTCAGGTCCTCTACCACGACTGGGAGGCCGAGACCTACGACGAGAAGTGGTCGATCTCGTACGACCAGCGCTGCATCGACTACGCGCGCGGCCGGTTCGACGCCATCGTGCCCGAGGACGAGCAGCGCAAACTGCCGTACGACCGGGCCCTCGAGCTGGGCTGCGGCACCGGGTTCTTCCTGCTCAACCTCATCCAGTCCGGCGTGGCGCGTCGCGGTTCGGTCACCGACCTGTCGCCCGGCATGGTCAAGGTGGCCACCCGCAACGGCCAGTCGCTGGGCCTCGACATCGACGGCCGCGTCGCCGACGCCGAAGGCATCCCGTACGAGGACGACACGTTCGACCTGGTCGTCGGGCATGCTGTGCTGCACCACATCCCCGACGTCGAACTGTCGCTGCGCGAGGTCGTACGCATCCTCAAGCCGGGCGGACGGTTCGTGTTCGCCGGCGAACCCACCACGGTGGGCAACCGGTACGCCCGCGAGCTGTCGACCCTGACGTGGCACGCGACCACGAACCTGACCAAGCTGCCGTTCCTGAGCGGCTGGCGGCGGCCCCAGGAAGAACTCGACGAGTCCTCACGCGCGGCCGCCCTTGAGGCCGTCGTCGACCTGCACACGTTCGATCCGGCGGACCTGGAGCGCATGGCCACCAACGCCGGTGCGGTCGAGGTGCGCACCGCCAGCGAGGAATTCACCGCCGCCATGCTGGGCTGGCCGGTCCGCACGTTCGAGGCCGCGGTGCCGCCGGGCCGTCTGGGCTGGGGCTGGGCCAAGTTCGCGTTCAACAGCTGGACCACGCTGAGCTGGGTGGACGCCAACGTCTGGCGCAAGGTCGTGCCGAAGGGCTGGTTCTACAACGTCATGGTCACGGGGGTCAAACCCTCCTGA

Protein Sequence 

>Ms2329_MSMEG2329_protein
MTEIRDAADPAPNPHATAEEVEAAMHDSKLAQVLYHDWEAETYDEKWSISYDQRCIDYARGRFDAIVPEDEQRKLPYDRALELGCGTGFFLLNLIQSGVARRGSVTDLSPGMVKVATRNGQSLGLDIDGRVADAEGIPYEDDTFDLVVGHAVLHHIPDVELSLREVVRILKPGGRFVFAGEPTTVGNRYARELSTLTWHATTNLTKLPFLSGWRRPQEELDESSRAAALEAVVDLHTFDPADLERMATNAGAVEVRTASEEFTAAMLGWPVRTFEAAVPPGRLGWGWAKFAFNSWTTLSWVDANVWRKVVPKGWFYNVMVTGVKPS

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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