fni
ms2337
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 2417887 – 2418912
Vulnerability Index (VI):
M. tuberculosis homologs
M. abscessus homologs MAB3242
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG2333 MSMEG2334 MSMEG2335 fni MSMEG2338 MSMEG2339 MSMEG2340 MSMEG2342
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms2337_fni_dna
TCGACGGATGGGGTTCGAACGCGGCCAGCGCGGGCCAGGCCTGCTCGGGTTCGGCCGGCGTCGGTGCCGCAGTCGCGAGCGCCAACGCGGCGCCGGTCGCCAGCGCCGCACACCCGGTGCGGAGTCTTCTGCGTTTCAGGCGTTGCGAGGCCACCCCTCGATTTTTGCGACCGTGTCGCGTCCGCGGACGCAGAATCTCGAGAATGCGGTGATTTCGCCGCGAGACGGGTATAGGGGTTTCGTCCGGCCCGGACACACCCGCTGCTTCACGAGAGGGAATCCATGACCGCATCGCGAGTGTGCGCGTGACGGGTGACCGGGACGCGGTGGCACGCAAGCGGCGCCACATCGACGTGTGCCTCAACGAGGCCGTCGACCACCAGAGCGTGTCGACCGGGCTCGAGCGCTACCGGCTGCCGTACCACGCGCTCACCCAGACCAACCTGACCGAGATCGATCTGACCACGAATTTTCTCGGCAAGCCGCTTCGTGCCCCGGTGCTGATCGGCGCCATGACCGGTGGTGCCGAGCTGTCCGGAACCATCAACCGCAATCTCGCCGCGGCCGCCCAGAAACTCGGCGTCGGGATGATGCTCGGTTCGCAACGGATCATGCTGCGCAGCGGTGAGCAGGCCGCGCACCGCTCCGAGAGCTTCGCAGTGCGTGACGTCGCCCCGGATGTGTTGCTGGTGGGCAACATCGGGCTGTCGCAGCTGACCCACGACAACGCGCCGTTGATCACCGACGCACTGCGGCGTGTGGGTGCCGACGCACTTGCGGTGCACACGAACCCCCTGCAGGAGGCGATCCAGGCCAACGGAGACACCGATTTCGCGGGATCACGTGAACGGCTCCTCGAAATCGGTCCATCCATCGGCTGCCCGCTGCTGCTCAAGGAGGTGGGCCACGGCATCGGCGCCGCGGCCGTCGCCGAGCTCACCGGCGGCCGCGACGATGTGCCGGTCGCGGCCATCGACGTCGCAGGTGCGGGCGGCACCTCGTGGTCACGCGTCGAGCAGTTCGTCCGCTACGGCACGGTGCGGTACCCGGATCTCGCGGACTGGGGCGTCCCGACCGCACGTGCCATCATCGAAGTGCGACAGGCGCTTCCGCGTATCCCGCTGGTCGCCTCGGGCGGCATCCGCACCGGTATGGACGCGGCAAAGGGGCTCTTCGCACTTGACGGTGTAGAGACGATCAGCTGCTTTCGCGCTGTGATCGAGGGGTCTGGTTGGCTTGGGGTGTGCCGGAGAAGAAGCGGAAGAGCAAGAGGAAGAGCGGAGTGTCCGGGGGCAGTGTGGACCTGGCGTTGCTGCAGAAGCTAA

Protein Sequence 

>Ms2337_Fni_protein
VRVTGDRDAVARKRRHIDVCLNEAVDHQSVSTGLERYRLPYHALTQTNLTEIDLTTNFLGKPLRAPVLIGAMTGGAELSGTINRNLAAAAQKLGVGMMLGSQRIMLRSGEQAAHRSESFAVRDVAPDVLLVGNIGLSQLTHDNAPLITDALRRVGADALAVHTNPLQEAIQANGDTDFAGSRERLLEIGPSIGCPLLLKEVGHGIGAAAVAELTGGRDDVPVAAIDVAGAGGTSWSRVEQFVRYGTVRYPDLADWGVPTARAIIEVRQALPRIPLVASGGIRTGMDAAKGLFALDGVETISCFRAVIEGSGWLGVCRRRSGRARGRAECPGAVWTWRCCRS

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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