MSMEG2818
ms2818
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 2880573 – 2881502
Vulnerability Index (VI):
M. tuberculosis homologs Rv1765A, Rv3475, Rv3380c, Rv3326, Rv3187, [+ 12 remaining orthologs]
M. abscessus homologs MAB2086c, MAB2088
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG2817 MSMEG2818 MSMEG2819 MSMEG2820
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms2818_MSMEG2818_dna
CCGTGAGCGGGCAGTTCGGATGTATGAGGACCGGATCGCGGAGTTCGGTGGTTCCAAGCGGGAAGCTCGTCGCCATGTGGGCGAGCTGCTGGGCATCAATGAGGCGACGTTGCGCAATTGGGTCGAGAACCGCCACGGTAGCGGGAGGCCTGCAGCGGGCGCGGTGATGTCTTCGGCAGGCGATAAGGACGCGGAGCTGGCCGCGCTGCGCAAGGAGAATGCTGAATTGCGCAGAGCCAACGAGATTCTCAAGACAGCATCGGCGTTTTTCGCCGCGGCGGAGGTCGACCGCCGACTGCGGTGATCGTCGACTACATCGACGCTTACCGCCACCGGTTCGGGGTCGACCCGATCTGCGCCGTGCTCTCCGAGCACGACATGCCGATCGCCCCGTCCACCTACTACGCGGCCAAGGCTCGCGGTCCGGTCAGCGACGCGGCCTGGGCCGAGGCGCACGCCGCCAACGCCGTCCATACGGTGTTCTGGGCCAACCGGGGTCTGTATGGGGTCCGCAAGATGTGGCATGCGATGCGACACGCTGGTCACGACATGGGCCGCGATCAGGTGGCCCGGCTGATGCGCATCTGTGGAATCTCGGGCGCGGTGCGCGGCAAACGCCGCACCATCACCACCGCCTCCGAGCAGGGTGCACCACGGCACCCGGATTTGATCGAGCGCAAGTGGGGCCTGCCGGTGCGCCCGGATCAGTGGTGGGTGGCTGATTTCACCTACACCTGGACGCTGGCGGGGTTCGTCTACACGGCGTTCTGTGTCGACGTGTTCTCCCGACGCATTCTGGGCTGGCGGGTGATGTCGACCAAGGCCACTCCGCTGGTGACCAGTGTGCTCGAGCAGGCGGTGTTCACTCGTCGTAGGACTGATTTCCGTTTCACTACAACGGGTTTGGTGCACCACTCGGATGCGGGAAGCCAATACACATCGCTGGCTTTCACCGACGCACTGCGCGACTCAGGGATCGCCGGCTCGATCGGATCGGTCGGCGACGCGCTCGACAACGCGTTGATGGAATCGGCGATCGGCCTCTACAAGACCGAGCTGATCGACCGCCACCAATCCTGGACCGGGCGTGCCGAAGTCGAACGCGAAACCGCGGCCTGGGTGCACTGGTACAACACCGACCGCCTGCACTCCTCCCTGAGCTACCAGTCGCCGATCGACTACGAGGCCCAGTACCGTAATGACGCCGCCTCAACACCGGAGGTGGCCTAA

Protein Sequence 

>Ms2818_MSMEG2818_protein
VIVDYIDAYRHRFGVDPICAVLSEHDMPIAPSTYYAAKARGPVSDAAWAEAHAANAVHTVFWANRGLYGVRKMWHAMRHAGHDMGRDQVARLMRICGISGAVRGKRRTITTASEQGAPRHPDLIERKWGLPVRPDQWWVADFTYTWTLAGFVYTAFCVDVFSRRILGWRVMSTKATPLVTSVLEQAVFTRRRTDFRFTTTGLVHHSDAGSQYTSLAFTDALRDSGIAGSIGSVGDALDNALMESAIGLYKTELIDRHQSWTGRAEVERETAAWVHWYNTDRLHSSLSYQSPIDYEAQYRNDAASTPEVA

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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