MSMEG4088
ms4088
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 4164825 – 4165133
Vulnerability Index (VI):
M. tuberculosis homologs Rv3474, Rv3381c, Rv3325, Rv3186, Rv3184, [+ 11 remaining orthologs]
M. abscessus homologs MAB2087
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG4085 ssuD MSMEG4087 MSMEG4088 MSMEG4089 MSMEG4090 ssuD
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms4088_MSMEG4088_dna
GGCCCATCCAGCGGGACGCAGGCCCATGCTATGGGACTTGCTCCGGACGCAGCCATCTTTAGGATCGTGCTGAATCGAAACCGAAGGTCGGTGATGGCGACGGCAGGCTTCTGACAGTCGACCTGTGGTAGCTACATGCCATTGCTGGGCTTGGCCGGTGGCATCGCTTGCCAGGCTGAGGAGTAGTCTCACCAGCACGCTGCGGCCATCTGACGGTCCCCGCTGGCTAGGGTCTGCTGCACGAACAGGTGACATCTGAGTTGGCTTGTCCAGCGTGGGCAGGCTGGAAGGATGTCCCCATGGCAAGGCCCTATCCCCGTGAGTTCCGCGACGACGTCGTGCGCGTGGCCCGCAACCGCGAAGACGGTGTGACGATCGAGCAGATCGCCACCGATTTCGGTGTGCACCCGATGACGCTGCACAAATGGCTTCGCCAGGCCGACATCGACGAGGGCACCAAGCCCGGTAGAACCACCGGCGAGTCCGGTGAGCTGCGTGAGGCCCGGCGTCGGATCAAGCTGCTCGAGCTGGAGAACGAGGTGCTGCGCCGGGCCGCGGCGTATCTGTCACAGGCCAACCTGCCGGGAAAAGGCTCTACCCGCTCGTGA

Protein Sequence 

>Ms4088_MSMEG4088_protein
MARPYPREFRDDVVRVARNREDGVTIEQIATDFGVHPMTLHKWLRQADIDEGTKPGRTTGESGELREARRRIKLLELENEVLRRAAAYLSQANLPGKGSTRS

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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