MSMEG4106
ms4106
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 4185561 – 4185869
Vulnerability Index (VI):
M. tuberculosis homologs Rv3474, Rv3381c, Rv3325, Rv3186, Rv3184, [+ 11 remaining orthologs]
M. abscessus homologs MAB2087
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG4103 MSMEG4104 MSMEG4105 MSMEG4106 MSMEG4107 pntB pntA
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms4106_MSMEG4106_dna
GCACTGGTAGTGGCCTCTGCCGGCAGCATCATGAGCGTCGTTGCACATCTCTGGAAGTGCCCTTCGGCGAGCTGGATCGCGATGTCTCGCACAGTGGCCAACGCGTCCGTGACAAAGCTGGTGGTGGGCCGCACTCGAACATCGGTGTGGTCACTCAACGAGCACGCGCACCTCGACCAGTTCGACGCAACAGGCCGGCGCTCACTGCTCACCCTGCGTTAATAACATCGGGGTCTGCTGCACGAACAGGTGACATCTGAGTTGGCTTGTCCAGCGTGGGCAGGCTGGAAGGATGTCCCCATGGCAAGGCCCTATCCCCGTGAGTTCCGCGACGACGTCGTGCGCGTGGCCCGCAACCGCGAAGACGGTGTGACGATCGAGCAGATCGCCACCGATTTCGGTGTGCACCCGATGACGCTGCACAAATGGCTTCGCCAGGCCGACATCGACGAGGGCACCAAGCCCGGTAGAACCACCGGCGAGTCCGGTGAGCTGCGTGAGGCCCGGCGTCGGATCAAGCTGCTCGAGCTGGAGAACGAGGTGCTGCGCCGGGCCGCGGCGTATCTGTCACAGGCCAACCTGCCGGGAAAAGGCTCTACCCGCTCGTGA

Protein Sequence 

>Ms4106_MSMEG4106_protein
MARPYPREFRDDVVRVARNREDGVTIEQIATDFGVHPMTLHKWLRQADIDEGTKPGRTTGESGELREARRRIKLLELENEVLRRAAAYLSQANLPGKGSTRS

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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