MSMEG4159
ms4159
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 4238141 – 4239460
Vulnerability Index (VI):
M. tuberculosis homologs Rv3431c
M. abscessus homologs
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon TSS Legend ? Ju, 2024 (4) Li, 2017 (5) (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 (5) PMID: 29326668 MSMEG4156 MSMEG4157 MSMEG4158 MSMEG4159 MSMEG4160 MSMEG4161 MSMEG4162 MSMEG4163 MSMEG4164
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms4159_MSMEG4159_dna
CAGGATGGGCGGTAATCGCGGTGTTCTGATCTTTATAGTTCTTCGCCATCCAGCGCAGCGCGCGGATCACGCGTTGATTGCGACCGATAGTGCCCCTTGGGGTGGTGGACTTCGGATCGGCGTGGGTGCACGCGTGGTGATCAACGAGTCGTGGTGAATGTTAGGGAGCAATGATCAATACCTGTGGATGAGCCTCGGTGTGGGGGCGTGAAGATGGGCGCACCTTCCCGGGGATGATCTTCACGGAATCAGGTATTCGATCAAGACCGGCGTTGGCGCGCTGGTTGGGAAGGTACGCCCATGCTCACCGTAGTTCACGACACCGAGGACGCCAACGACAAGGCCAGCGGTGCTGGTCGGTCGTTGTTGGATGAGATCGTCCGCGACGGGGCCCGGCAGATGCTGGCCGCGGCGTTGCAGGCCGAGGTCGCCGCCTACGTGGCGCAGTTCGCCGATCAACTCGACGAGAACGGTCACCGGTTGGTGGTGCGAAACGGCTATCACCAGCCCCGGGAGGTGCTGACCGCCGCCGGCGCGGTGCAGGTGAAAGCGCCGCGGGTCAACGACCGCCGTGTCGACCCCGACACCGGTGAACGCAAGCGGTTCTCCTCGGCGATCCTGCCGGCCTGGGCGCGCAAGTCGCCGCAGATGAGCGAGGTACTGCCGCTGCTGTACCTGCACGGCCTGTCGAGCAACGATTTCACCCCTGCCCTCGAGCAGTTCCTCGGCTCCGGCGCTGGGCTGTCGGCCAGCACGATCACCCGGCTCACGGCGCAGTGGCAAGACGAGGCCCGCGCGTTTGGGGCCCGCGACCTCTCGGCCACTGATTACGTGTATCTGTGGGTCGACGGCATTCACCTCAAGGTGCGGCTGGACCAGGAAAAGCTCTGTCTGCTGGTGATGCTGGGCGTGCGTGCTGATGGCCGCAAGGAGCTCGTGGCGATCACCGACGGCTACCGCGAGTCGGCCGAGTCGTGGGCCGATCTGTTGCGCGACTGCAAGCGCCGCGGCATGACCGCCCCCGTACTCGCGATCGGCGATGGCGCGCTCGGGTTCTGGAAAGCAGTCCGCGAGGTTTTCCCGGCCACCAAAGAGCAGCGGTGCTGGTTTCATAAGCAGGCCAATGTTCTTGCTGCACTGCCGAAATCAGCGCACCCGTCGGCGCTGGCGGCGATCAAGGAGATCTACAACGCCGAGGATATCGACAAGGCCCAGATCGCGGTCAAGGCCTTCGAGGCCGACTTCGGCGCGAAGTATCCCAAGGCGGTCGCTAAGATCACCGACGACCTCGATGTGCTGCTGGAATTCTACAAGTATCCGGCCGAACATTGGATTCATCTGCGAACGACGAATCCGATCGAATCCACCTTTGCCACAGTGCGTTTGAGGACCAAGGTCACCAAGGGGCCCGGATCACGAGCGGCCGGACTAGCGATGGCCTACAAGCTCATCGACGCCGCCGCGGCCCGCTGGCGTGCCGTCAACGCCCCACACCTGGTCGCCCTGGTCCGCGCCGGCGCGGTCTTCCATAAAGGCAGACTGCTCGAACGACCCACCGACATCACCCCGCCAACATCGCCCTCAGACGGCGGTCAGCACGCCGGAACGGAGGTCGCCTGA

Protein Sequence 

>Ms4159_MSMEG4159_protein
MLTVVHDTEDANDKASGAGRSLLDEIVRDGARQMLAAALQAEVAAYVAQFADQLDENGHRLVVRNGYHQPREVLTAAGAVQVKAPRVNDRRVDPDTGERKRFSSAILPAWARKSPQMSEVLPLLYLHGLSSNDFTPALEQFLGSGAGLSASTITRLTAQWQDEARAFGARDLSATDYVYLWVDGIHLKVRLDQEKLCLLVMLGVRADGRKELVAITDGYRESAESWADLLRDCKRRGMTAPVLAIGDGALGFWKAVREVFPATKEQRCWFHKQANVLAALPKSAHPSALAAIKEIYNAEDIDKAQIAVKAFEADFGAKYPKAVAKITDDLDVLLEFYKYPAEHWIHLRTTNPIESTFATVRLRTKVTKGPGSRAAGLAMAYKLIDAAAARWRAVNAPHLVALVRAGAVFHKGRLLERPTDITPPTSPSDGGQHAGTEVA

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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