MSMEG4403
ms4403
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 4493176 – 4494498
Vulnerability Index (VI):
M. tuberculosis homologs Rv2810c, Rv3349c
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG4400 MSMEG4401 MSMEG4402 MSMEG4403 MSMEG4404 MSMEG4405 MSMEG4406 MSMEG4407 MSMEG4408 MSMEG4409 MSMEG4410
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms4403_MSMEG4403_dna
TCCGGTCGCACGGGGTATCTCACCTTTTCAAACACCTGCTCGTCTTGCCAGTAGCCGCCACTCGTGGTGCAACTGTAGGTGCCGCAACTCGTGCGGATGGGCACGTAATGAGCCGGTATCCACACCATGCGATAGCGCACCCAGCTTCCGTCCGGCCGCATCGGTTCGTCGCAGATGCTGCGCGTTTGGGGGCTCTTCGCAGTTGAGGGTGTAGAGGTCGTCGGCGCGTCGGTGCCGGGATAGGGGTCGAGGTCTTCCGATGATGGAGGTTCCTACGCCATCCATCTGAAAGACCTCGACGTGCCTGACGCTACCGGTCGGGCGGGCTTCGCCTGCGCTGACCTGACGACTTTCTGCCGCCTCGACGAGCTCGGGTTGGAGGTGACCGGCCAACGCCTCGACCCTGATCGGGCCGTGCTGGCGTGCCGGGTCGCCGATGAGGATCGGTGGTGCCGCCGCTGCGGCGAAGAAGGCGTTGTACGTGACAGCGTGACTCGCACGTTGGCTCATGAACCGTTCGGGTGGCGACCCACGGCTTTGCTGGTCACGATCCGCCGTTACCGTTGCGCCGGCTGCGCTCATGTGTGGCGCCAGGATGCCAGCGCCGCAGCCGAACCGCGGGCCAGGCTGTCCCGGCGTGCTCTGCGGTGGGCGCTGGAAGCCCTTGTCTGCCAACACCTGTCGGTGGCCCGGGTCGCCGAGGCGCTTGCGGTGTCGTGGAACACTGCCAACAACGCCGTGCTCGCCGAAGGTCAGCGGGTGCTCATCGCCGATCCGGCCCGGTTCGATGGCGTCGCGGTGATCGGCGTCGATGAGCACGTGTGGCGGCACACTCGCCGCGGCGACAAGTACGTCACCGTCATCATCGATCTCACGCCCGTGCGTGACGGGACCGGCCCCGCACGGCTGCTCGACATGGTGGAGGGCCGCTCCAAGAAGGCGTTCGCCGACTGGCTGGCACAGCGGCCACAGGAGTGGCGTGATCGTGTGGACGTTGTTGCCATGGACGGGTTCTCCGGGTTCAAGACCGCCGCCACCGAAGAACTGCCTGACGCGGCCACGGTGATGGACCCCTTCCACGTGGTCCGCCTGGCCGGCAACGCCCTCGACGAGTGCCGACGCCGCGTGCAGCTGGCCACCTGCGGGCACCGCGGCCGCAGCACCGACCCGCTCTACCGATCGCGACGCACCCTGCACACCGGGGCCGACCTGCTCACCGACCGCCAGAAAGCCCGACTGGCCGCACTGTTCGCCGCCAACGCGCACGCCGAGATCGAGGCCACCTGGGCGATGTATCAACGCACCGTGGCCGCCTACCGCGAACCAGACCGCACCAAGGGCCGCACCATGATGGCTGCACTGATCACCACGCTGAGCACAGGCGTCCCCACGTCGCTGACCGAGCTGATCACCCTCGGGCGGACACTGAAGAAGCGTGCCGCCGACGTCCTGGCCTACTTCGACCGCCCCGGCACCTCCAACGGGCCGACCGAAGCGATCAACGGCCGCCTCGAACACCTGCGCGGATCCGCCCTGGGCTTCCGCAACCTCACCAACTACATCGCCCGGTCCCTGCTCGAGACCGGAGGCTTCCGAACCCAGCTCCGTCAACCTCGGCGGTGA

Protein Sequence 

>Ms4403_MSMEG4403_protein
VPDATGRAGFACADLTTFCRLDELGLEVTGQRLDPDRAVLACRVADEDRWCRRCGEEGVVRDSVTRTLAHEPFGWRPTALLVTIRRYRCAGCAHVWRQDASAAAEPRARLSRRALRWALEALVCQHLSVARVAEALAVSWNTANNAVLAEGQRVLIADPARFDGVAVIGVDEHVWRHTRRGDKYVTVIIDLTPVRDGTGPARLLDMVEGRSKKAFADWLAQRPQEWRDRVDVVAMDGFSGFKTAATEELPDAATVMDPFHVVRLAGNALDECRRRVQLATCGHRGRSTDPLYRSRRTLHTGADLLTDRQKARLAALFAANAHAEIEATWAMYQRTVAAYREPDRTKGRTMMAALITTLSTGVPTSLTELITLGRTLKKRAADVLAYFDRPGTSNGPTEAINGRLEHLRGSALGFRNLTNYIARSLLETGGFRTQLRQPRR

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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