MSMEG5379
ms5379
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 5457760 – 5458461
Vulnerability Index (VI):
M. tuberculosis homologs
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG5375 MSMEG5376 MSMEG5377 MSMEG5378 MSMEG5379 MSMEG5380 MSMEG5381
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms5379_MSMEG5379_dna
GGAAAAAGGCACACTCATCTGCACGTCCGTTACGGGAGGGCGGTTACCGTTCTGTCGTAGTCGTGTCTCAGTTCTTCAGTCTCACACTGTGATCGCAGTGAAGCGCGGAACTACCGGATAGGCGCGGAGGAGCGTGTATCGCGATGCTCGACGGTCTGCTCCTCAATCTACACAGGAGGTTTAGTGGCTCTTCGCACTTGACGGTGTAGAGACGATCAGCTGCTTTCGCGCTGTGATCGAGGGGTCTGGTTGGCTTGGGGTGTGCCGGAGAAGAAGCGGAAGAGCAAGAGGAAGAGCGGAGTGTCCGGGGGCAGTGTGGACCTGGCGTTGCTGCAGAAGCTAATGGCCGACGCTGGTCGGAACGTGTTCGCGGGAATGTTCGATGAGCCGACGCCCGAGGTGCGGGCGGTGCCGGATCGTGCGCGGGGCTTCCGGGTGCGCGTCGACCTGATGTACGCCAAGCCGCCGATCTGGCGTCGGCTGGACCTGCCGGGCGACCTCATGCTCGATGAGCTCCATGTTGTGCTGCAGGTCGTTATGGGCTGGCAGGACAGTCATCTGCATAAGTTCGGTGTCGGGGCGGACCGGCGGACCCGTGCCTACTTCGTCACCGGGTTTGATCTCAGCGAAGGCGACGACGGTGTCGTCGAGGACAGCGTGCGCCTCGATCAGGTGGTGTCCGATAAGGGCGAGCGGTTGTTCTACGATTACGACTTCGGCGACGGATGGGACCACGTGCTCGTGGTCGAAGACGTTTTCGATGATCCGCCCCCGGCTGCGGTGTGTCTGACGGGAAAGATGGCCTGTCCGCCGGAGGACTGTGGTGGCCTGGGCGGCTATGAGGAGTTGGCTGCGTGGGTTCGCGGCGGGTACGACCCGCGGGAAACGCCGATGGGACTCGGTGCGCAGGAGATGAGGGACTGGCTGCCCCGGGGCTGGCACCCCGACCGTTTCTCGGTGGCCGAGACCAATGACGCTCTGGCCGCGTTGAACACGCGTTGA

Protein Sequence 

>Ms5379_MSMEG5379_protein
VSGGSVDLALLQKLMADAGRNVFAGMFDEPTPEVRAVPDRARGFRVRVDLMYAKPPIWRRLDLPGDLMLDELHVVLQVVMGWQDSHLHKFGVGADRRTRAYFVTGFDLSEGDDGVVEDSVRLDQVVSDKGERLFYDYDFGDGWDHVLVVEDVFDDPPPAAVCLTGKMACPPEDCGGLGGYEELAAWVRGGYDPRETPMGLGAQEMRDWLPRGWHPDRFSVAETNDALAALNTR

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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