MSMEG6461
ms6461
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 6526946 – 6527449
Vulnerability Index (VI):
M. tuberculosis homologs
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG6459 MSMEG6460 MSMEG6461 MSMEG6462 MSMEG6463 MSMEG6464
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms6461_MSMEG6461_dna
CACGGGCGTGAGATCGATGATGACGGTGACGTACTTGTCGCCGCGGCGAGTGTGCCGCCACACGTGCTCATCGACGCCGATCACCGCGACGCCATCGAACCGGGCCGGATCGGCGATGAGCACCCGCTGACCTTCGGCGAGCACGGCGTTGTTGGCAGTGTTCCACGACACCGCAAGCGCCTCGGCGACCCGGGCCACCGACAGGTGTTGGCAGACAAGGGCTTCCAGCGCCCACCGCAGAGCACGCCGGGACAGCCTGGCCCGCGGTTCGGCTGCGGCGCTGGCATCCTGGCGCCACACATGAGCGCAGCCGGCGCAACGGTAACGGCGGATCGTGACCAGCAAAGCCGTGGGTCGCCACCCGAACGGTTCATGAGCCAACGTGCGAGTCACGCTGTCACGTACAACGCCTTCTTCGCCGCAGCGGCGGCACCACCGATCCTCATCGGCGACCCGGCACGCCAGCACGGCCCGATCAGGGTCGAGGCGTTGGCCGGTCACCTCCAACCCGAGCTCGTCGAGGCGGCAGAAAGTCGTCAGGTCAGCGCAGGCGAAGCCCGCCCGACCGGTAGCGTCAGGCACGTCGAGGTCTTTCAGATGGATGGCGTAGGAACCTCCATCATCGGAAGACCTCGACCCCTATCCCGGCACCGACGCGCCGACGACCTCTACACCCTCAACTGCGAAGAGCCGGTTTGGGCCCAGGGTCGTGTGGAACTCAATTACCAAGCCGGTCAGGGGAATTCGGCAAAACCACGCAATCATCCGACGATTGTGGCCCGGCTGGATATTCAGCATAGTTAG

Protein Sequence 

>Ms6461_MSMEG6461_protein
MSAAGATVTADRDQQSRGSPPERFMSQRASHAVTYNAFFAAAAAPPILIGDPARQHGPIRVEALAGHLQPELVEAAESRQVSAGEARPTGSVRHVEVFQMDGVGTSIIGRPRPLSRHRRADDLYTLNCEEPVWAQGRVELNYQAGQGNSAKPRNHPTIVARLDIQHS

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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