MSMEG6462
ms6462
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 6527168 – 6528490
Vulnerability Index (VI):
M. tuberculosis homologs Rv2810c, Rv3349c
M. abscessus homologs
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon TSS Legend ? Ju, 2024 (4) Li, 2017 (5) (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 (5) PMID: 29326668 MSMEG6459 MSMEG6460 MSMEG6461 MSMEG6462 MSMEG6463 MSMEG6464 MSMEG6465
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms6462_MSMEG6462_dna
ACGGCTTTGTGTCCCACACGCCATAAGTGGGGAAAACGATAGGACAGAAACCGTGCGACATGCCAACTTAGCCGACCCTAACTATGCTGAATATCCAGCCGGGCCACAATCGTCGGATGATTGCGTGGTTTTGCCGAATTCCCCTGACCGGCTTGGTAATTGAGTTCCACACGACCCTGGGCCCAAACCGGCTCTTCGCAGTTGAGGGTGTAGAGGTCGTCGGCGCGTCGGTGCCGGGATAGGGGTCGAGGTCTTCCGATGATGGAGGTTCCTACGCCATCCATCTGAAAGACCTCGACGTGCCTGACGCTACCGGTCGGGCGGGCTTCGCCTGCGCTGACCTGACGACTTTCTGCCGCCTCGACGAGCTCGGGTTGGAGGTGACCGGCCAACGCCTCGACCCTGATCGGGCCGTGCTGGCGTGCCGGGTCGCCGATGAGGATCGGTGGTGCCGCCGCTGCGGCGAAGAAGGCGTTGTACGTGACAGCGTGACTCGCACGTTGGCTCATGAACCGTTCGGGTGGCGACCCACGGCTTTGCTGGTCACGATCCGCCGTTACCGTTGCGCCGGCTGCGCTCATGTGTGGCGCCAGGATGCCAGCGCCGCAGCCGAACCGCGGGCCAGGCTGTCCCGGCGTGCTCTGCGGTGGGCGCTGGAAGCCCTTGTCTGCCAACACCTGTCGGTGGCCCGGGTCGCCGAGGCGCTTGCGGTGTCGTGGAACACTGCCAACAACGCCGTGCTCGCCGAAGGTCAGCGGGTGCTCATCGCCGATCCGGCCCGGTTCGATGGCGTCGCGGTGATCGGCGTCGATGAGCACGTGTGGCGGCACACTCGCCGCGGCGACAAGTACGTCACCGTCATCATCGATCTCACGCCCGTGCGTGACGGGACCGGCCCCGCACGGCTGCTCGACATGGTGGAGGGCCGCTCCAAGAAGGCGTTCGCCGACTGGCTGGCACAGCGGCCACAGGAGTGGCGTGATCGTGTGGACGTTGTTGCCATGGACGGGTTCTCCGGGTTCAAGACCGCCGCCACCGAAGAACTGCCTGACGCGGCCACGGTGATGGACCCCTTCCACGTGGTCCGCCTGGCCGGCAACGCCCTCGACGAGTGCCGACGCCGCGTGCAGCTGGCCACCTGCGGGCACCGCGGCCGCAGCACCGACCCGCTCTACCGATCGCGACGCACCCTGCACACCGGGGCCGACCTGCTCACCGACCGCCAGAAAGCCCGACTGGCCGCACTGTTCGCCGCCAACGCGCACGCCGAGATCGAGGCCACCTGGGCGATGTATCAACGCACCGTGGCCGCCTACCGCGAACCAGACCGCACCAAGGGCCGCACCATGATGGCTGCACTGATCACCACGCTGAGCACAGGCGTCCCCACGTCGCTGACCGAGCTGATCACCCTCGGGCGGACACTGAAGAAGCGTGCCGCCGACGTCCTGGCCTACTTCGACCGCCCCGGCACCTCCAACGGGCCGACCGAAGCGATCAACGGCCGCCTCGAACACCTGCGCGGATCCGCCCTGGGCTTCCGCAACCTCACCAACTACATCGCCCGGTCCCTGCTCGAGACCGGAGGCTTCCGAACCCAGCTCCGTCAACCTCGGCGGTGA

Protein Sequence 

>Ms6462_MSMEG6462_protein
VPDATGRAGFACADLTTFCRLDELGLEVTGQRLDPDRAVLACRVADEDRWCRRCGEEGVVRDSVTRTLAHEPFGWRPTALLVTIRRYRCAGCAHVWRQDASAAAEPRARLSRRALRWALEALVCQHLSVARVAEALAVSWNTANNAVLAEGQRVLIADPARFDGVAVIGVDEHVWRHTRRGDKYVTVIIDLTPVRDGTGPARLLDMVEGRSKKAFADWLAQRPQEWRDRVDVVAMDGFSGFKTAATEELPDAATVMDPFHVVRLAGNALDECRRRVQLATCGHRGRSTDPLYRSRRTLHTGADLLTDRQKARLAALFAANAHAEIEATWAMYQRTVAAYREPDRTKGRTMMAALITTLSTGVPTSLTELITLGRTLKKRAADVLAYFDRPGTSNGPTEAINGRLEHLRGSALGFRNLTNYIARSLLETGGFRTQLRQPRR

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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