ML0316
mL0316
Possible transcriptional regulator (TetR family)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 404708 – 405310
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0316_ML0316_dna
TGTCCGTTCCTAGATCAGGATTGAGTGTTCAGATGGCGCAACCCGCACGGCCGCTGCGTGCCGACGCGGCGCGAAACCGTGCCCGAATACTGGGTGTTGCTTACGAAGCTTTCGCGACCGAGGGCTTGTCGGTGCCGATTGACGAAATTGCCCGACGCGCGGGTGTCGGAGCTGGCACTGTATACCGGCATTTTCCGACGAAGGAGGCGCTGTGTGCGGCGGTCATCGGGGACCGCATGCCTCACCTCGTAGACGACGGGTATGTGCTGTTGAAGTCTGCCGGGCCGGGTGAGGCGCTGTTCACCTATCTGCGCTCGCTCGTGTTGCACTGGGGCGCTACCGACCGCGGACTGGTTGATGCGCTGGCCGGCGCCGGTGGTATCGACATCCTCGGCGTCGCGCCCGACGCCGAGGATGCGTTTTTGACTATACTCAGTGACCTGCTGTACGCGGCGCAATATGCGGGCACCGCGCGCACTGACGTCGGCGTCCGCGAGGTCAAATCGATCCTGGTCGGATGCCAAGCGATGGAAGCGTACAACTCGGCATTGGCTGAGCGGGTGACCGATGTCGTTGTCGATGGTTTGCGCGCGGCGCGATAGC

Protein Sequence 

>ML0316_ML0316_protein
CPFLDQD_VFRWRNPHGRCVPTRRETVPEYWVLLTKLSRPRACRCRLTKLPDARVSELALYTGIFRRRRRCVRRSSGTACLTS_TTGMCC_SLPGRVRRCSPICARSCCTGALPTADWLMRWPAPVVSTSSASRPTPRMRF_LYSVTCCTRRNMRAPRALTSASARSNRSWSDAKRWKRTTRHWLSG_PMSLSMVCARRDS

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding ML0316 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

12 show weak predicted evidence for PPIs

View all pooled AlphaFold results for ML0316

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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