ino2
mL0396c
Probable myo-inositol-1-phosphate synthase Ino2 (Inositol 1-phosphate synthetase) (D-glucose 6-phosphate cycloaldolase) (Glucose 6-phosphate cyclase) (Glucocycloaldolase)
M. leprae · TN
[TnSeq DB] [SeqHub]
TN Coordinates: 492715 – 493824
Vulnerability Index (VI):
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>mL0396c_ino2_dna
TATGAGTGAGCACAACCCAGCAGGGGCGCCAGGGGCGTCGACTGAGGTAAGAGTAGCCATTGTCGGCGTGGGCAACTGCGCGTCCTCGCTAGTTCAAGGTATCGAGTACTACCAGAACGCTGACGACACATCGACAGTGCCCGGTCTTATGCACGTGCGGTTCGGACCCTACCATGTGCGTGATGTTAAATTCGTGGCGGCCTTCGACGTAGACGCCAAGAAGGTCGGCGTAGACTTGTCGGACGCGATCTTCACCTCAGAGAACAACACCATCAAGATCGCCGACGTGCCACCCACCAATGTGGTGGTGCAGCGCGGCCCAACACTGGACGGCATCGGCAAGTACTACACCGACACCATTGAGCTGTCAGACGTTCCACCCGTCGACGTAGTCCAGGCACTAACAGAAGCCAAGACAGACGTGCTGGTGTCCTACCTGCCGGTGGGTTCCGAAGAAGCCGACAAGTTCTATGCCCAGTGCGCCATCAACGCCCGCGTAGCGTTCGTGAACGCGCTGCCGGTGTTCATCGCCTCCGACCCAGTGTGGGCCAAAAAATTCGCCGACGCCAGGGTACCGATCGTAGGTGATGACATTAAGAGCCAGGTCGGCGCAACCATCACTCACCGGGTGATGGCCAAGCTGTTTGAGGACCGCGGGGTGCAGCTGGACCGCACCATGCAACTCAACGTGGGCGGCAACATGGACTTCCTGAATATGCTCGAGCGCGAACGGGTGCAATCCAAGAAGATCTCCAAGACCCAGGCCGTAACGTCGAACGTGCATCGGGAATTCAATACCAAAGACATCCACATCGGTCCGTCAGACCACGTCGGCTGGCTCGATGACCGCAAATGGGCCTACGTCCGACTGGAAGGCCGTGGTTTCGGCGATGTGCCGCTGAACCTCGAATACAAGCTCGAGGTATGGGACTCACCGAACTCAGCGGGCGTCATCATCGACGCGGTACGGGCAGCAAAGATAGCCAAGGACCGAGGGATCGGTGGACCAGTGATCCCGGCTTCATCCTACCTGATGAAAAGCCCGCCGCAACAGCTACCCGACGAGATCGCGCGTGCCCAGCTCGAAGAGTTCATCATCGACACCAAATA

Protein Sequence 

>ML0396c_Ino2_protein
YE_AQPSRGARGVD_GKSSHCRRGQLRVLASSRYRVLPER_RHIDSARSYARAVRTLPCA_C_IRGGLRRRRQEGRRRLVGRDLHLREQHHQDRRRATHQCGGAARPNTGRHRQVLHRHH_AVRRSTRRRSPGTNRSQDRRAGVLPAGGFRRSRQVLCPVRHQRPRSVRERAAGVHRLRPSVGQKIRRRQGTDRR__H_EPGRRNHHSPGDGQAV_GPRGAAGPHHATQRGRQHGLPEYARARTGAIQEDLQDPGRNVERASGIQYQRHPHRSVRPRRLAR_PQMGLRPTGRPWFRRCAAEPRIQARGMGLTELSGRHHRRGTGSKDSQGPRDRWTSDPGFILPDEKPAATATRRDRACPARRVHHRHQI

No essentiality data available for this gene.

AlphaFold Protein Interactions

Protein–protein interactions (PPIs) were predicted by co-folding Ino2 with every other protein in the M. leprae proteome using a pooled-AlphaFold3 based approach (Horia et al.). The size-corrected interface predicted template modeling (sciPTM) score indicates confidence in the predicted interaction: weak evidence (sciPTM > 0.05), intermediate evidence (sciPTM > 0.2), or strong evidence (sciPTM > 0.4).

0 proteins show strong predicted evidence for PPIs

1 shows intermediate predicted evidence for PPIs

2 show weak predicted evidence for PPIs

View all pooled AlphaFold results for Ino2

Use of these data is subject to the AlphaFold Server Output Terms of Use.

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