cysA3
rv3117
thiosulfate sulfurtransferase CysA3
M. tuberculosis · H37Rv
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H37Rv Coordinates: 3483971 – 3484804
Vulnerability Index (VI):
M. smegmatis homologs MSMEG5789, MSMEG1809
M. abscessus homologs MAB0740c, MAB3641
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 Rv3114 Rv3115 moeB2 cysA3 sseC1 moaE1 Rv3120 cyp141
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>rv3117_cysA3_dna
CTTCCTCTTGGTCGACGTGCGAGAGCCCGCCGAGTTCGACATCGCGCACATTCCGGGCAGCATCTTGATACCCAAAGGCGAAATCGGCTCGGCGGCGGGCCTAGCCCAGCTACCGCTGGACAAGGAAATTGTCCTGTACTGCAAGAGTGGAATCCGATCGGCCCAGGCGCTAACCACGTTGAAAGCAGCCGGACTGCACAACGTGAAGCATCTCGACGGCGGTATCGCGGAGTGGACACGAACCATCGACTCCTCCTTGTTGGTGTACTAGCACCGAACTATGCGAAAGGATTCCCGCCATGGCACGCTGCGATGTCCTGGTCTCCGCCGACTGGGCTGAGAGCAATCTGCACGCGCCGAAGGTCGTTTTCGTCGAAGTGGACGAGGACACCAGTGCATATGACCGTGACCATATTGCCGGCGCGATCAAGTTGGACTGGCGCACCGACCTGCAGGATCCGGTCAAACGTGACTTCGTCGACGCCCAGCAATTCTCCAAGCTGCTGTCCGAGCGTGGCATCGCCAACGAGGACACGGTGATCCTGTACGGCGGCAACAACAATTGGTTCGCCGCCTACGCGTACTGGTATTTCAAGCTCTACGGCCATGAGAAGGTCAAGTTGCTCGACGGCGGCCGCAAGAAGTGGGAGCTCGACGGACGCCCGCTGTCCAGCGACCCGGTCAGCCGGCCGGTGACCTCCTACACCGCCTCCCCGCCGGATAACACGATTCGGGCATTCCGCGACGAGGTCCTGGCGGCCATCAACGTCAAGAACCTCATCGACGTGCGCTCTCCCGACGAGTTCTCCGGCAAGATCCTGGCCCCCGCGCACCTGCCGCAGGAACAAAGCCAGCGGCCCGGACACATTCCTGGTGCCATCAACGTGCCGTGGAGCAGGGCCGCCAACGAGGACGGCACCTTCAAGTCCGATGAGGAGTTGGCCAAGCTTTACGCCGACGCCGGCCTAGACAACAGCAAGGAAACGATTGCCTACTGCCGAATCGGGGAACGGTCCTCGCACACCTGGTTCGTGTTGCGGGAATTACTCGGACACCAAAACGTCAAGAACTACGACGGCAGTTGGACAGAATACGGCTCCCTGGTGGGCGCCCCGATCGAGTTGGGAAGCTGA

Protein Sequence 

>Rv3117_CysA3_protein
MARCDVLVSADWAESNLHAPKVVFVEVDEDTSAYDRDHIAGAIKLDWRTDLQDPVKRDFVDAQQFSKLLSERGIANEDTVILYGGNNNWFAAYAYWYFKLYGHEKVKLLDGGRKKWELDGRPLSSDPVSRPVTSYTASPPDNTIRAFRDEVLAAINVKNLIDVRSPDEFSGKILAPAHLPQEQSQRPGHIPGAINVPWSRAANEDGTFKSDEELAKLYADAGLDNSKETIAYCRIGERSSHTWFVLRELLGHQNVKNYDGSWTEYGSLVGAPIELGS

Essentiality:

Call Condition Type Source Notes
Growth Advantage in vitro TnSeq [DeJesus et al. (2017)]
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]

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