MSMEG1019
ms1019
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1087851 – 1089971
Vulnerability Index (VI):
M. tuberculosis homologs nrdE
M. abscessus homologs MAB3413c
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 dinB MSMEG1015 MSMEG1016 MSMEG1017 MSMEG1019 MSMEG1021 MSMEG1022 MSMEG1023
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1019_MSMEG1019_dna
CCGGACATCAACGCTGGGGGCTACGTCCCCAAGCAGGTCATCGCGTTCCTCAACAACGAACACAACCGGTCGTTGATCCGCGGCGTCATCGCCGCGGGCAACAACAACTTCGGTGCGGAGTTCGCCTATGCGGGCAATGTGATCGCGCGCAAGTGTGGCGTGCCGTACCTGTATCGCTTCGAACTGATGGGTACCCCGGACGATGTGGAAGCCGTCCGGGCAGGTTTGAAAGACTTCTGGAAGGAACAGACGTGCCACCCACCGTCACAGCTGCAGAGCCTGTAACCACCACCGGGCACGTGTTGCCGGGGGAGGCGGATTACCACGCGCTCAACGCGATGCTGAATCTGTACGACGCCGACGGCAAGATTCAGTTCGAAAAGGACAGGGAAGCCGCCAAGCAGTACTTCCTGCAGCACGTCAACCAGAACACGGTCTTCTTCCACAGCCAGGACGAGAAGCTCGACTACCTGATCGAGAACGAGTACTACGAGCGCGAGGTGCTCGACCAGTACTCCCGCGACTTCATCAAGAGCCTGCTGGACCGCGCGTACGCCAAGAAGTTTCGGTTCCCCACGTTCCTCGGTGCGTTCAAGTACTACACGTCCTACACGCTGAAGACCTTCGACGGTAAGCGCTACCTGGAGCGTTTCGAGGACCGCGTCGTCATGGTCGCGTTGACCCTGGCCGCAGGCGACACCGAACTCGCCGAGAAACTCGTCGACGAGATCATCGACGGCCGGTTCCAGCCGGCCACCCCCACGTTCCTCAACTCGGGCAAGAAGCAGCGCGGCGAGCCGGTGTCCTGCTTCCTGTTGCGCATCGAGGACAACATGGAGTCCATCGGGCGTTCCATCAACTCGGCGCTGCAGCTGTCCAAGCGCGGCGGCGGAGTCGCGCTGCTGCTGAGCAACATCCGCGAGCACGGCGCGCCCATCAAGAACATCGAGAACCAGAGCTCGGGCGTCATCCCCATCATGAAGCTGCTGGAGGACTCGTTCTCCTACGCCAATCAGCTGGGTGCCCGTCAGGGCGCGGGCGCGGTGTACCTGCACGCCCACCACCCCGACATCTACCGGTTCCTGGACACCAAGCGCGAGAACGCCGACGAGAAGATCCGGATCAAGACGCTCTCGCTGGGTGTCGTGATCCCCGACATCACCTTCGAGCTGGCCAAGAAGAACGAGGACATGTACCTGTTCTCGCCGTACGACGTCGAGCGCGTCTACGGGGTGCCGTTCGCCGACGTCTCGGTCACCGAGAAGTACTACGAGATGGTCGACGACGCGCGGATCCGCAAGACCAAGATCAACGCGCGCGAGTTCTTCCAGACGCTGGCCGAGCTGCAGTTCGAATCGGGCTACCCGTACATCATGTTCGAGGACACCGTGAACCGGTCCAACCCGATCGCGGGCAAGATCACGCACTCGAACCTGTGCTCGGAGATCCTGCAGGTCTCCACGCCGTCGGAGTTCAACGACGACCTGTCCTACGCCAAGGTGGGCAAGGACATCTCCTGCAACCTCGGCTCGCTCAACATCGCCAAGGCCATGGACTCGCCGGACTTCGCGCAGACCATCGAGGTGGCGATCCGTGCGCTCACCGCGGTGAGCGATCAGACCCACATCACGTCCGTGCCGTCGATCGAGCAGGGCAACAACGATTCCCACGCCATCGGCCTGGGGCAGATGAACCTGCACGGATACCTTGCGCGGGAACGCATCTACTACGGTTCCGAAGAGGGCATCGACTTCACGAACATCTACTTCTACACGGTGCTGTTCCACGCGCTGCGCGCGTCGAACAAGATCGCGATCGAGCGCGGGACGCACTTCAAGGGATTCGAGAAGTCCAAGTACGCCTCGGGCGAGTTCTTCGACAAGTACACCGATCAGGTGTGGGAGCCCAAGACCGACAAGGTGCGCCGGCTGTTCGCCGACGCCGATATCCACATCCCCACGCAGGACGACTGGAAGCAGTTGAAGGAGTCGGTGCAGAAGCACGGCATCTACAACCAGAACCTGCAGGCCGTCCCGCCGACGGGGTCGATCTCCTACATCAACCACTCGACGTCGTCGATCCACCCGGTCGCGTCGAAGATCGAGATCCGCAAGGAAGGCAAGATCGGTCGCGTCTACTACCCGGCGCCGTACATGACCAACGACAACCTGGACTACTACCAGGACGCGTATGAGATCGGGTACGAGAAGATCATCGACACCTACGCCGCGGCCACCCAGCACGTGGACCAGGGTCTGAGCCTGACGTTGTTCTTCAAGGACACCGCCACCACGCGTGACGTGAACAAGGCCCAGATCTACGCATGGCGCAAGGGCATCAAGACGCTCTACTACATCCGCCTGCGCCAGATGGCCTTGGAGGGAACCGAAGTCGAGGGTTGCGTCAGCTGCATGCTGTGA

Protein Sequence 

>Ms1019_MSMEG1019_protein
VLPGEADYHALNAMLNLYDADGKIQFEKDREAAKQYFLQHVNQNTVFFHSQDEKLDYLIENEYYEREVLDQYSRDFIKSLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLERFEDRVVMVALTLAAGDTELAEKLVDEIIDGRFQPATPTFLNSGKKQRGEPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLSNIREHGAPIKNIENQSSGVIPIMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKKNEDMYLFSPYDVERVYGVPFADVSVTEKYYEMVDDARIRKTKINAREFFQTLAELQFESGYPYIMFEDTVNRSNPIAGKITHSNLCSEILQVSTPSEFNDDLSYAKVGKDISCNLGSLNIAKAMDSPDFAQTIEVAIRALTAVSDQTHITSVPSIEQGNNDSHAIGLGQMNLHGYLARERIYYGSEEGIDFTNIYFYTVLFHALRASNKIAIERGTHFKGFEKSKYASGEFFDKYTDQVWEPKTDKVRRLFADADIHIPTQDDWKQLKESVQKHGIYNQNLQAVPPTGSISYINHSTSSIHPVASKIEIRKEGKIGRVYYPAPYMTNDNLDYYQDAYEIGYEKIIDTYAAATQHVDQGLSLTLFFKDTATTRDVNKAQIYAWRKGIKTLYYIRLRQMALEGTEVEGCVSCML

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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