fni
ms1057
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1124625 – 1125650
Vulnerability Index (VI):
M. tuberculosis homologs
M. abscessus homologs MAB3242
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG1053 MSMEG1054 MSMEG1055 fni MSMEG1058 MSMEG1059 MSMEG1060 MSMEG1061
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1057_fni_dna
TCGACGGATGGGGTTCGAACGCGGCCAGCGCGGGCCAGGCCTGCTCGGGTTCGGCCGGCGTCGGTGCCGCAGTCGCGAGCGCCAACGCGGCGCCGGTCGCCAGCGCCGCACACCCGGTGCGGAGTCTTCTGCGTTTCAGGCGTTGCGAGGCCACCCCTCGATTTTTGCGACCGTGTCGCGTCCGCGGACGCAGAATCTCGAGAATGCGGTGATTTCGCCGCGAGACGGGTATAGGGGTTTCGTCCGGCCCGGACACACCCGCTGCTTCACGAGAGGGAATCCATGACCGCATCGCGAGTGTGCGCGTGACGGGTGACCGGGACGCGGTGGCACGCAAGCGGCGCCACATCGACGTGTGCCTCAACGAGGCCGTCGACCACCAGAGCGTGTCGACCGGGCTCGAGCGCTACCGGCTGCCGTACCACGCGCTCACCCAGACCAACCTGACCGAGATCGATCTGACCACGAATTTTCTCGGCAAGCCGCTTCGTGCCCCGGTGCTGATCGGCGCCATGACCGGTGGTGCCGAGCTGTCCGGAACCATCAACCGCAATCTCGCCGCGGCCGCCCAGAAACTCGGCGTCGGGATGATGCTCGGTTCGCAACGGATCATGCTGCGCAGCGGTGAGCAGGCCGCGCACCGCTCCGAGAGCTTCGCAGTGCGTGACGTCGCCCCGGATGTGTTGCTGGTGGGCAACATCGGGCTGTCGCAGCTGACCCACGACAACGCGCCGTTGATCACCGACGCACTGCGGCGTGTGGGTGCCGACGCACTTGCGGTGCACACGAACCCCCTGCAGGAGGCGATCCAGGCCAACGGAGACACCGATTTCGCGGGATCACGTGAACGGCTCCTCGAAATCGGTCCATCCATCGGCTGCCCGCTGCTGCTCAAGGAGGTGGGCCACGGCATCGGCGCCGCGGCCGTCGCCGAGCTCACCGGCGGCCGCGACGATGTGCCGGTCGCGGCCATCGACGTCGCAGGTGCGGGCGGCACCTCGTGGTCACGCGTCGAGCAGTTCGTCCGCTACGGCACGGTGCGGTACCCGGATCTCGCGGACTGGGGCGTCCCGACCGCACGTGCCATCATCGAAGTGCGACAGGCGCTTCCGCGTATCCCGCTGGTCGCCTCGGGCGGCATCCGCACCGGTATGGACGCGGCAAAGGGGCTCTTCGCACTTGACGGTGTAGAGACGATCAGCTGCTTTCGCGCTGTGATCGAGGGGTCTGGTTGGCTTGGGGTGTGCCGGAGAAGAAGCGGAAGAGCAAGAGGAAGAGCGGAGTGTCCGGGGGCAGTGTGGACCTGGCGTTGCTGCAGAAGCTAA

Protein Sequence 

>Ms1057_Fni_protein
VRVTGDRDAVARKRRHIDVCLNEAVDHQSVSTGLERYRLPYHALTQTNLTEIDLTTNFLGKPLRAPVLIGAMTGGAELSGTINRNLAAAAQKLGVGMMLGSQRIMLRSGEQAAHRSESFAVRDVAPDVLLVGNIGLSQLTHDNAPLITDALRRVGADALAVHTNPLQEAIQANGDTDFAGSRERLLEIGPSIGCPLLLKEVGHGIGAAAVAELTGGRDDVPVAAIDVAGAGGTSWSRVEQFVRYGTVRYPDLADWGVPTARAIIEVRQALPRIPLVASGGIRTGMDAAKGLFALDGVETISCFRAVIEGSGWLGVCRRRSGRARGRAECPGAVWTWRCCRS

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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