MSMEG1053
ms1053
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1121728 – 1123011
Vulnerability Index (VI):
M. tuberculosis homologs Rv3035
M. abscessus homologs MAB3379
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG1050 MSMEG1051 MSMEG1052 MSMEG1053 MSMEG1054 MSMEG1055 fni MSMEG1058
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1053_MSMEG1053_dna
CACCATGCCGCGGGTGATGATGTGCGGGTTGGCCAGCTTGAACTTGAGCAGCCGCCAGTACCGCACCAGGTACCAGGGCGTGAACGCCCGGTTGGCGATGACCCACTTCAGCGACGCCATGGTCAGGAAGTCGGCTTGACGCGGATCGCGCAGACGCGAGCCCCGCCACCGCTTGTGAATCGGTGCGCCCCACATCGTCGTCATGGCCGGAAAGCCTACGCGAGGCTTTCCGGGCGCTCGGGTTACCCTCACGTGGTCCACAACTCAACGATCTGTCCGGTCTCTCGACGAAAGGACACCGTGTTCCGGCGATACCTGGCGCTCATGGTGGCTGCGCTGCTCACGGGCCTTCTCGCCGGTTGTGAGAACACCGATTCCTGGGTCCAGGCCAGCCCTGCCTCCGGTTGGGCCGCGCAATACGCCGACGCCGCCAACAGCAGCTACAAAAGTGCTCCCGGAGCCCAGTCGCTGCGCGCGGAGTGGAGCCGGTCGGCCAAAGGTGAGGTAGGCGCCCAGGTCGCCCTGGGTTCGGCCGGTTATCTCGCGGTCAACGCCCAGAGCGCGGGCGGGTGTTCGCTGATGGTGTGGGAGGCCGACAACAACGGCCGCCAGCGCTGGTGCACGCGTCTGGTGCAGGGCGGCGGATGGTCGGGCCCGCTGTTCGATGGCTTCGACAACGTCTATGTGGGCCAGCCCGGCGCGATGCTGTCCTTTCCTCCCACGCAGTGGATCCGCTGGCGTAAGCCCGTGATCGGGATGCCGACCACCCCGCGACTGCTGGCCGACGGGCAACTCCTCGTGGTCACGCACCTCGGCCAGGTGCTGGTGTTCGACTCCCACCGCGGCACGGTCGAGGGCACACCTCTCGATCTGGTGTCGGGCGTGGACCCGACCGATTCCGAGCGCGGTCTGGCCGACTGCCCGCTGGCCCGGTCGCGGTGCCCCGTCGCGGCGGCGCCCGCGTTCTCCGGCCAGACCAACATCGTGGTGCTGAGCCTGTGGCAGCCCGGTGCCGAGGCCCCGGTGCTGGTCGGCCTGAACTACCGGCCCGGGCAGAAGCCGCTGCTGACGCAGGCGTGGACCAGTGACGCCGCGGGCCGCGGCCCGCTGGCCAGCCCGGTGCTGTCCGCGGACGGCCAGACCGTCTACGTCAGCGGGCGCGACGAGCAACTGTGGGCGCTGAACTCCGCGGACGGGACCGTCAAATGGTCCGTGCCGCTCGACTATCTCGCCCAGACGCCGCCGTCGGTGGCGCCGGACGGTCTGATCGTGGCGGGCGGCGGTCCCGACGCCAAGCTGACCGCGGTGCGCGACGAGGGTGACCGCGGCGAGATCGTGTGGACGCGTGACGACGTCGCTCCCCTGACCACGTCGAGTCGTTCCGGAAACGTCGGCTACGCCGTGGCGCGGCAGGGCGGCCACGGGCAGGCCCTGCTGGTCTTCGACACCGGTGACGGCCGCACGCTGCAGACCCATCCGCTTCCCGAGGCCACCGGCTGGCCGGTCGGGGTATCGATCGGCCACGACGGCCGCGTGGTCACCGCGACGAGTGACGGGCAAGTGTATGGCTTCTCACCGGCATGA

Protein Sequence 

>Ms1053_MSMEG1053_protein
VFRRYLALMVAALLTGLLAGCENTDSWVQASPASGWAAQYADAANSSYKSAPGAQSLRAEWSRSAKGEVGAQVALGSAGYLAVNAQSAGGCSLMVWEADNNGRQRWCTRLVQGGGWSGPLFDGFDNVYVGQPGAMLSFPPTQWIRWRKPVIGMPTTPRLLADGQLLVVTHLGQVLVFDSHRGTVEGTPLDLVSGVDPTDSERGLADCPLARSRCPVAAAPAFSGQTNIVVLSLWQPGAEAPVLVGLNYRPGQKPLLTQAWTSDAAGRGPLASPVLSADGQTVYVSGRDEQLWALNSADGTVKWSVPLDYLAQTPPSVAPDGLIVAGGGPDAKLTAVRDEGDRGEIVWTRDDVAPLTTSSRSGNVGYAVARQGGHGQALLVFDTGDGRTLQTHPLPEATGWPVGVSIGHDGRVVTATSDGQVYGFSPA

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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