MSMEG1728
ms1728
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1821176 – 1821511
Vulnerability Index (VI):
M. tuberculosis homologs Rv3474, Rv3381c, Rv3325, Rv3186, Rv3184, [+ 11 remaining orthologs]
M. abscessus homologs
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 29326668 (5) PMID: 38418874 MSMEG1723 MSMEG1724 MSMEG1725 MSMEG1726 MSMEG1727 MSMEG1728 MSMEG1729 MSMEG1730 MSMEG1731 MSMEG1732
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1728_MSMEG1728_dna
GGCAGCATCTAGTGTCGCGCGTCTGAAGTTTGTTTACGAGTGTGGGGCAGGATTTCGTCGGCGGTCTTGGTCCACACGAATGGGTGGGCGCGTTGGTTCCAGCCCTCGATGAAGGCGCTGATGGCAGCGATGAGTTCTTTAACGCTGTTGAACGAGCCCCGGCGGATTTCTTGGCGGGTGATGATCGAGAAGAACACCTCGACCAGGTTCAACCAGGAGCCTGAGGTCGGGGTGAAATGCAGTGTCATGAACCGTCCTGGATCTGGTGGAGACCGTGATCGCACCAGGAGGATGTGGTTGTGGCTGCGCCGAGAAAGTTCGACCAAGAGACCCGTGAGCGGGCAGTTCGGATGTATGAGGACCGGATCGCGGAGTTCGGTGGTTCCAAGCGGGAAGCTCGTCGCCATGTGGGCGAGCTGCTGGGCATCAATGAGGCGACGTTGCGCAATTGGGTCGAGAACCGCCACGGTAGCGGGAGGCCTGCAGCGGGCGCGGTGATGTCTTCGGCAGGCGATAAGGACGCGGAGCTGGCCGCGCTGCGCAAGGAGAATGCTGAATTGCGCAGAGCCAACGAGATTCTCAAGACAGCATCGGCGTTTTTCGCCGCGGCGGAGGTCGACCGCCGACTGCGGTGA

Protein Sequence 

>Ms1728_MSMEG1728_protein
VAAPRKFDQETRERAVRMYEDRIAEFGGSKREARRHVGELLGINEATLRNWVENRHGSGRPAAGAVMSSAGDKDAELAALRKENAELRRANEILKTASAFFAAAEVDRRLR

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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