MSMEG1730
ms1730
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1821508 – 1822437
Vulnerability Index (VI):
M. tuberculosis homologs Rv1765A, Rv3475, Rv3380c, Rv3326, Rv3187, [+ 12 remaining orthologs]
M. abscessus homologs MAB2086c, MAB2088
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG1724 MSMEG1725 MSMEG1726 MSMEG1728 MSMEG1730 MSMEG1731 MSMEG1732
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1730_MSMEG1730_dna
CGTGAGCGGGCAGTTCGGATGTATGAGGACCGGATCGCGGAGTTCGGTGGTTCCAAGCGGGAAGCTCGTCGCCATGTGGGCGAGCTGCTGGGCATCAATGAGGCGACGTTGCGCAATTGGGTCGAGAACCGCCACGGTAGCGGGAGGCCTGCAGCGGGCGCGGTGATGTCTTCGGCAGGCGATAAGGACGCGGAGCTGGCCGCGCTGCGCAAGGAGAATGCTGAATTGCGCAGAGCCAACGAGATTCTCAAGACAGCATCGGCGTTTTTCGCCGCGGCGGAGGTCGACCGCCGACTGCGGTGATCGTCGACTACATCGACGCTTACCGCCACCGGTTCGGGGTCGACCCGATCTGCGCCGTGCTCTCCGAGCACGACATGCCGATCGCCCCGTCCACCTACTACGCGGCCAAGGCTCGCGGTCCGGTCAGCGACGCGGCCTGGGCCGAGGCGCACGCCGCCAACGCCGTCCATACGGTGTTCTGGGCCAACCGGGGTCTGTATGGGGTCCGCAAGATGTGGCATGCGATGCGACACGCTGGTCACGACATGGGCCGCGATCAGGTGGCCCGGCTGATGCGCATCTGTGGAATCTCGGGCGCGGTGCGCGGCAAACGCCGCACCATCACCACCGCCTCCGAGCAGGGTGCACCACGGCACCCGGATTTGATCGAGCGCAAGTGGGGCCTGCCGGTGCGCCCGGATCAGTGGTGGGTGGCTGATTTCACCTACACCTGGACGCTGGCGGGGTTCGTCTACACGGCGTTCTGTGTCGACGTGTTCTCCCGACGCATTCTGGGCTGGCGGGTGATGTCGACCAAGGCCACTCCGCTGGTGACCAGTGTGCTCGAGCAGGCGGTGTTCACTCGTCGTAGGACTGATTTCCGTTTCACTACAACGGGTTTGGTGCACCACTCGGATGCGGGAAGCCAATACACATCGCTGGCTTTCACCGACGCACTGCGCGACTCAGGGATCGCCGGCTCGATCGGATCGGTCGGCGACGCGCTCGACAACGCGTTGATGGAATCGGCGATCGGCCTCTACAAGACCGAGCTGATCGACCGCCACCAATCCTGGACCGGGCGTGCCGAAGTCGAACGCGAAACCGCGGCCTGGGTGCACTGGTACAACACCGACCGCCTGCACTCCTCCCTGAGCTACCAGTCGCCGATCGACTACGAGGCCCAGTACCGTAATGACGCCGCCTCAACACCGGAGGTGGCCTAA

Protein Sequence 

>Ms1730_MSMEG1730_protein
VIVDYIDAYRHRFGVDPICAVLSEHDMPIAPSTYYAAKARGPVSDAAWAEAHAANAVHTVFWANRGLYGVRKMWHAMRHAGHDMGRDQVARLMRICGISGAVRGKRRTITTASEQGAPRHPDLIERKWGLPVRPDQWWVADFTYTWTLAGFVYTAFCVDVFSRRILGWRVMSTKATPLVTSVLEQAVFTRRRTDFRFTTTGLVHHSDAGSQYTSLAFTDALRDSGIAGSIGSVGDALDNALMESAIGLYKTELIDRHQSWTGRAEVERETAAWVHWYNTDRLHSSLSYQSPIDYEAQYRNDAASTPEVA

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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