MSMEG1857
ms1857
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1934812 – 1936173
Vulnerability Index (VI):
M. tuberculosis homologs
M. abscessus homologs
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG1854 MSMEG1855 MSMEG1856 MSMEG1857 MSMEG1858 MSMEG1859 MSMEG1860 MSMEG1861 MSMEG1862
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1857_MSMEG1857_dna
CGTTCTTGGTGTCAACAGGCATGGTGGCACCGCATGCTCAGGCTCCGTTCTTTTTCAGTCGCTGTAATCAGCTTCTCATCGCGGTGCGGGTACTCATGACAGCAGTTAGCGCACCAAGTACGTGAAGTAATTGCCGAGAGATTCCAGAGCCCGGGGCGAGATGACTGCGCTCACTGAAATTCCCCACTGACGCTCATTGAAATTCCCCACCCGTGTGGCTCCGCCGAGAAGGGCGGGCCTCCCTCGATGCTGCTGGTGTCTGACGCCAACAGCTCCCGTCGAAGGAGGCCCGCTTTCTCATGCTCACATGGGAGGACGATGTGGAAGTACATGCCCTACGTAAACGTGGTTGGACGATCTCGGCGATCGCCCGCCACACCGGCCGGGACCGCAAAACGATCGCGGATTATTTGTCGGGAAAGCGAACACCTGGGGTGCGGGCGCGGCCGGGCCCGGATCCGTTCGAGCCGTTCGTCGACTATGTCGCCGCGCGGCTGACCGAGGACCCGCATCTGTGGGCCCGCACCCTGCTCGACGAACTCGAGCAGCTGGGATTTCCGCTGTCGTATCAGAGCCTGACCCGCAACATCCGGGCGAGGAACCTGCGCCCGGACTGCCAGGCGTGTCGCACCGCCACCGAACGCCCGAACTCCGTCATCGAGCACGCTCCTGGCGATGAAACCCAGTGGGACTGGCTGGAATTGCCCGATCCACCCGAATCCTGGGGGTGGGGTAAGACCGCACATCTGCTGGTGGGCTCGCTGGCGCATTCTGGCAAGTGGCGGGCGGCGTTGACGCCGTCGGAGGATCAGCCGCAGCTGGTCGCCGCGCTGGACCGGGTGACCCGCGAGCTCGGTGGCTGCACGCGGGTGTGGCGGTTTGACCGGATGGCCACCGTCTGTGACCCGGGTTCGGGGCGGGTGACCGCGTCGTTTGCCGGGGTGGCCAAGCATTACGGGGTGTCGGTGGCGATCTGCCCACCGCGGCGGGGAAACCGCAAGGGTGTGGTGGAGAAGGTCAATCACACTGCCGCGCAACGCTGGTGGCGCACCCTGGATGACGAGTTGACCGCCGAGGCGGCGCAGGCCAGTGTGGACCGGTTTGCCCGGGTGCGCGGTGGCACCCGGATGCGGGCCACCGCTGACGGGCGGTCAGCGGTGGCTGTGGTGGCCAAGACCGAACCCTTGGCGCCAGTGCCGGCGACGCCGTATCCGGTGATCATTTCCCAAACCCGCACGGCGTCACGCCAAGCGTTGGTGTCCTACCGCGGCAACCGCTACTCGGTGCCGCCGGAGCTGGCCGCCGCCCAGGTGGTGGTCAGCCATCCCGTCGGGGCGCAGTTCTGCGATATCGCCACGGTCGCAGGGATAGTGATCGCGCGGCACCGCATGGCCGCCGACGGACTCGGGGTGATGGTCCGCGACAGCGGCCATGTCATCGCCCTGGACACCATGGCGATGGCGACAGCGTCCACCGGGCGTCCCCATCGCCGCAAGGAACGCATCCCACCCGGGCCGGCCGCCAAAGCCGCTGCCGCCCAACTGCTTCACCTCAACGACGCTAACCAAGAAGCTGCCGAATCCTCCACTTGGTCAACTGATTCCACTGTCATCGACCTGTCCGCCTATGAGCGGGCCGCCCAGAAAAGGACCATCCAATGA

Protein Sequence 

>Ms1857_MSMEG1857_protein
MLTWEDDVEVHALRKRGWTISAIARHTGRDRKTIADYLSGKRTPGVRARPGPDPFEPFVDYVAARLTEDPHLWARTLLDELEQLGFPLSYQSLTRNIRARNLRPDCQACRTATERPNSVIEHAPGDETQWDWLELPDPPESWGWGKTAHLLVGSLAHSGKWRAALTPSEDQPQLVAALDRVTRELGGCTRVWRFDRMATVCDPGSGRVTASFAGVAKHYGVSVAICPPRRGNRKGVVEKVNHTAAQRWWRTLDDELTAEAAQASVDRFARVRGGTRMRATADGRSAVAVVAKTEPLAPVPATPYPVIISQTRTASRQALVSYRGNRYSVPPELAAAQVVVSHPVGAQFCDIATVAGIVIARHRMAADGLGVMVRDSGHVIALDTMAMATASTGRPHRRKERIPPGPAAKAAAAQLLHLNDANQEAAESSTWSTDSTVIDLSAYERAAQKRTIQ

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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