MSMEG1858
ms1858
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1936170 – 1937024
Vulnerability Index (VI):
M. tuberculosis homologs Rv3638
M. abscessus homologs
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon TSS Legend ? Ju, 2024 (5) Li, 2017 (4) (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 29326668 (5) PMID: 38418874 MSMEG1855 MSMEG1856 MSMEG1857 MSMEG1858 MSMEG1859 MSMEG1860 MSMEG1861 MSMEG1862 MSMEG1863
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1858_MSMEG1858_dna
GTCGCAGGGATAGTGATCGCGCGGCACCGCATGGCCGCCGACGGACTCGGGGTGATGGTCCGCGACAGCGGCCATGTCATCGCCCTGGACACCATGGCGATGGCGACAGCGTCCACCGGGCGTCCCCATCGCCGCAAGGAACGCATCCCACCCGGGCCGGCCGCCAAAGCCGCTGCCGCCCAACTGCTTCACCTCAACGACGCTAACCAAGAAGCTGCCGAATCCTCCACTTGGTCAACTGATTCCACTGTCATCGACCTGTCCGCCTATGAGCGGGCCGCCCAGAAAAGGACCATCCAATGACCCCCACGCCACGGACCGCCAAGAACACCGCCACCGTCACCGAGGAGCCGCCGTCGACGGCGGCCAGCCGCTATCAGAAGCTGCGTTCACATCTGGCTGAGCTCAAACTGCACGCCGCCGCCGCGGCGCTGCCCGCCGTGCTCGACCAGGCCAGCGCCGAGAACCTGTCACTGACCGTGGCGTTGGAGCGGCTGCTGGCGGTCGAGGTCGAGGCCAGCACCGCCCGGCGGCTGGCTGGGCGGCTGCGGTTCGCCTGCCTGCCCACCCCGGCCACCCTCGATGATTTCGACGTCGATGCAGCCGCCGGCATCGACCGCAAGCTCATCGACGAACTGGGCACCTGCCGTTACCTCGAGTCGGCGACCAACATTCTGCTCGTCGGCCCGCCGGGCACCGGGAAGACGCACCTGTCGGTGGGGTTGGCAAGGGCGGCAGCGCATGCCGGGTATCGGACCTACTTCACCACTGCCGCCGATCTGGCAGCTCGGTGCCATCGCGCGGCGATTGAGGGGCGCTGGGCCACCACCATGCGGTTCTACGCCGGCCCCACCCTGTTGGTGATCGATGAACTGGGCTATTTGCCGCTGCCTGCCGAGGCCGCCTCGGCGTTGTTTCAGGTTGTCTCCCAACGGTATTTGAAAACCAGCATCGTGATCACGACCAATCGTGGTGTCGGATCCTGGGGAGAGATCCTCGGCGACACCACCGTGGCCGCCGCCATGCTCGACCGCCTCCTGCACCGCTCGGTGGTCATCAACCTCGACGGCGAGTCCTACCGCCTTCGCGACCACCAGGCCGCCGCGGAAACCCTCCGCCGCGCCACCACCGGCACCCGCCAAGCACTACACTGA

Protein Sequence 

>Ms1858_MSMEG1858_protein
MTPTPRTAKNTATVTEEPPSTAASRYQKLRSHLAELKLHAAAAALPAVLDQASAENLSLTVALERLLAVEVEASTARRLAGRLRFACLPTPATLDDFDVDAAAGIDRKLIDELGTCRYLESATNILLVGPPGTGKTHLSVGLARAAAHAGYRTYFTTAADLAARCHRAAIEGRWATTMRFYAGPTLLVIDELGYLPLPAEAASALFQVVSQRYLKTSIVITTNRGVGSWGEILGDTTVAAAMLDRLLHRSVVINLDGESYRLRDHQAAAETLRRATTGTRQALH

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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