MSMEG2286
ms2286
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 2368918 – 2369979
Vulnerability Index (VI):
M. tuberculosis homologs Rv3168, fadE36
M. abscessus homologs MAB4910c, MAB0327, MAB4589c
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG2282 MSMEG2283 MSMEG2285 MSMEG2286 MSMEG2287 MSMEG2288 MSMEG2289
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms2286_MSMEG2286_dna
CAACGCCGATCATGTCCGAACGCTGCTCGGCGATGGGATCGAGGACTTCGAGACGCAGCGTCGCTCGTTGACGGTGGACATGTTCGCCGACGGAGCCGCCTTCCGCGACTTCTTCAAGGCCAACTACGGTCCCACCATCGCGGCCTACCGCGCCGTCGGTGACGACGCCGAACGCACCGCGGCGCTCGACGAGGCCATCGCCTTGCTGGGGGACCGATATCTCGATTCCGGTGCCATGCAGTGGGAGTACTTGGTGGTGACTGCACACAAACGCTGAGCGCCGCTGGCACGATGTCAGCATGCCCGGTGATGTGCAGCAGTTGCCCACGTTGAGCGAACACGACCAGCAGGCCCTGCAGGCGTGGGTCCGATCCGAGAAGATCGGATCCACTGTCAGCGATGTGGAACCCCTGACCGGCGGCACGCAGAACATCGTCGTGCGCGTCCACGTCGACGGACGCCCGATGGTGCTGCGGCGCCCGCCGGCCCATCCGCGGCCCACGAGCGACAAGACCATGCTGCGCGAGATCGCGGTGCTGCGCACCCTGGCCGGTTCCGGTGTGCCACATCCCGGGTTCATCGCGGGTTGCGCCGATCTGGACGTGCTGGGCGTGGTGTTCTACCTCATGGAGGAGGTGGTCGGGTTCAACCCGGGCAACGAGGTCGCCCCCGCCTACCAACGCGCCGACATGCGCCACGCGGTGGGCCTGTCCTACGCCGCGAGCCTCGCCGGCCTGGGCAACGCGGGGTGGGAGAACAGCGAACTCGCCGCGCTGCGGCGTCCGGGATCCTTTCTCGCACGCCAGGTTCCGCAGTTCCTCAAACTGCTCGAGAGCTATCGCCACGACAACTACCAGCCCGAGTCGATGGCCGGGGCGCAGCCGCTGGCGCAGTGGCTCGACGAACACCGACCGCCCGACGGCGAGCCGGGGATCATGCACGGCGACGCGCACCTGAACAACGTACTGCTGCGCCGTGAGGTCCCCGAGCTCGCGGCGTTCATCGACTGGGAGATGTGCACGATCGGAGATCCGCTGCTGGACCTCGGCTGGATGCTGGTGTGCTGGCCCGACGACCCCAACCCGATCAACGCCGGTTCGGCGCTCGCGGCCCTCGGTGGCCTGGCGACGCGAGCCGAACTACTCGACGCGTACCGGGCGGCCGGCGGCCGACAAACCGACCATCTCGACTGGTATGTGGCCCTTGCGTGTTTCAAGCTCGGCATCGTCATCGAGGGCACATGGTCGCGCTACCTCGCCGGGCAGGCCAACCGCGAGGCCGGCGAACAACTCCACGCCTCGGCCGAGAATCTCATGACCCTCGGCCTGCAGGTGACCAAGGGCGACAGCCCGTTCCGCTGA

Protein Sequence 

>Ms2286_MSMEG2286_protein
MPGDVQQLPTLSEHDQQALQAWVRSEKIGSTVSDVEPLTGGTQNIVVRVHVDGRPMVLRRPPAHPRPTSDKTMLREIAVLRTLAGSGVPHPGFIAGCADLDVLGVVFYLMEEVVGFNPGNEVAPAYQRADMRHAVGLSYAASLAGLGNAGWENSELAALRRPGSFLARQVPQFLKLLESYRHDNYQPESMAGAQPLAQWLDEHRPPDGEPGIMHGDAHLNNVLLRREVPELAAFIDWEMCTIGDPLLDLGWMLVCWPDDPNPINAGSALAALGGLATRAELLDAYRAAGGRQTDHLDWYVALACFKLGIVIEGTWSRYLAGQANREAGEQLHASAENLMTLGLQVTKGDSPFR

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

You do not have permission to view notes.