MSMEG2285
ms2285
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 2368080 – 2368895
Vulnerability Index (VI):
M. tuberculosis homologs Rv1403c, Rv1405c, menH, Rv3038c, Rv1377c, [+ 1 remaining orthologs]
M. abscessus homologs MAB3930c, MAB3381c, MAB0868c, MAB4613, MAB4018
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 MSMEG2281 MSMEG2282 MSMEG2283 MSMEG2284 MSMEG2285 MSMEG2286 MSMEG2287 MSMEG2288 MSMEG2289
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms2285_MSMEG2285_dna
TCAACTGCGAAGAGCCTGAAATGGGTACTGCCCAACAGCAGTTCCCGCACCACGAGCAGGGTCCAGCGTTCATCGAGCAGTTCCATGGCTTTGGCGACGGGGCAGAACTGGCCATAGGTCGACATGTGCGGCACCTTCCGGACAATTGCGCAACTGCGCACACCTGAGCACAAGTACACCGCGCAAACGTCGCCGAGCCAATACAGAATTTGAACCACAGGTAGTACAGATCTGTTACTGGATTCCTGTACCGGCGCGGCGGGACCATGACTGACACATGCCGAACCGAAGGAGTCACCATGGGCGTCGTCACCGTCGATCGAGAACTTGAGGCCAAACACCGGGCGCTGTGGGCGCTCGGGAACTACGGGGCGATCGCCGCCCATATCGTCGCACCGCTGGGACCCGTCCTCGTCGAGGCCTGCGGTATCGGACCCGGGGACCGGGTGCTCGACATCGCGGCAGGCACGGGCAACGCCTCGATCCCCGCCGCGCTGGCAGGCGCTCAGGTCACCGCGAGCGACCTGTGCCCGCAACTGGTCGACGAGGGCGCACACGAGTCCGCCGAGCGAGGCGTGGACATCACGTGGAAAGAGGCCAACGCCGAGGCGCTGCCGTTCTCCGACGGCGAGTTCGACGTCGTGATGTCCTGCATCGGCGTGATGTTCGCGCCGCATCACGACCAGTCCGCTCGGGAGCTGTTGCGGGTCACGCGTTCCGGTGGACGGATCGGTCTGATCAGCTGGACCCCAGAGGGTTTCATCGGGCAGCTGTTCGCGACCATGAAGCCGTTCGTTCCCGCGCCGCCGCCGGGCGTGTCGCCACCGCCGTTGTGGGGCAACGCCGATCATGTCCGAACGCTGCTCGGCGATGGGATCGAGGACTTCGAGACGCAGCGTCGCTCGTTGACGGTGGACATGTTCGCCGACGGAGCCGCCTTCCGCGACTTCTTCAAGGCCAACTACGGTCCCACCATCGCGGCCTACCGCGCCGTCGGTGACGACGCCGAACGCACCGCGGCGCTCGACGAGGCCATCGCCTTGCTGGGGGACCGATATCTCGATTCCGGTGCCATGCAGTGGGAGTACTTGGTGGTGACTGCACACAAACGCTGA

Protein Sequence 

>Ms2285_MSMEG2285_protein
MGVVTVDRELEAKHRALWALGNYGAIAAHIVAPLGPVLVEACGIGPGDRVLDIAAGTGNASIPAALAGAQVTASDLCPQLVDEGAHESAERGVDITWKEANAEALPFSDGEFDVVMSCIGVMFAPHHDQSARELLRVTRSGGRIGLISWTPEGFIGQLFATMKPFVPAPPPGVSPPPLWGNADHVRTLLGDGIEDFETQRRSLTVDMFADGAAFRDFFKANYGPTIAAYRAVGDDAERTAALDEAIALLGDRYLDSGAMQWEYLVVTAHKR

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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