MSMEG2315
ms2315
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 2396241 – 2397821
Vulnerability Index (VI):
M. tuberculosis homologs
M. abscessus homologs MAB4836c, MAB1277
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG2311 MSMEG2312 nrdF2 MSMEG2314 MSMEG2315 MSMEG2317 MSMEG2318
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms2315_MSMEG2315_dna
GATGTCACGGCGTGGTTCGAGGTGCCCGCGGCGCAGCGCGGCGCGGGCCCCGACCCGGCCAATCCGGAAGGGCAGGACGTCGCCGCGGTCACGCTGTGCGATGCGGCCAGAGCGGTCTCCATCGACTGTTCGGTGATCACCGAACCGGGGCGGCATGACTGGGTTTTCGCCAACACCGCGTTCGCCAGGGCCCTGCCATGGCTGGCCGGCCAACTGCACACGCCTGGCGTCGCGGCTGTGCCGCTGCCGGCGTCTACGTTGGGGCAGCAGCCCACAAACGTCCGGGCGGCCCCGCGCTAGTGCTCGCGGGTGCGGCCGAGGCGTCACCGGGTGTGCTAACTGTTGACCATGCAGCCAACACAAAGTTCGGCCGCGCGATGACCACCACGACGACCGGGGCCGACATCGAAACGTCCCCGCCACGGTTCGCCCGGGCAGGGGTGGGCGCGGTCGCCGCGGTCAGCTCGATCGCCCTGCTGGTCTTCCTCGATCGTTATGGCTACTTCGGCGACGAGCTGTATTTCCTGTCCGCGGGGCGGCGACTGTCTTTCGGCTACGCAGACCAGGGGCCTGCCCTGCCGCTCATCGCCCACGTCCTCGATAGCGTCGCACCGGGCTCGCTGTTCGTGCTGCGCCTGCCGGCGGTCCTCGCCACCGCGGCGGCGATCGTGATCAGCGCCCAGATCGCCCGCGAATTCGGAGGTGGGCGAGGTGCGCAGCTGCTCGCCGCCGGCGGATACGCCACGTCACCGTTTCTGCTGGTCCAAGGCGGACAGCTGGCCACCAACTCGTTCGACATCCCGCTGTGGGTGTTGATCACCTGGCTGCTGGTGCGGTGGGCACGCACCCGCGACGACCGCCTGCTGCTGTGGGCCGCTGTCGCCACCGCGTTTGCCCTGCAGATCAAGTGGCTTGTCCCCATCCTGTGGATCTGCGTCGGGTTGAGCGTCCTGCTGGTGGGGCCACGAGAGTTGTTGCGCCGCAGATTCTTGTGGGTCGGTGCTGCCGGCGCCGCGCTCACCACGATACCGATGCTGGTGTGGCAGGCCGGCAATGGTTGGCCACAACTGGCGATGGGAAGCGTGATCGCGGCCGAAAACGACACGGTGGGCGGTCGGCCTGCGTTCGTGCCGCTCGCGTTGTTCATCGCCGGACTGCTCGGCGGTGTGCTGCTGCTGTGCGGGGTGTGGGCGCTGTTGCGCTGGGAACCGTTGCGGCCGTTCCGCTTTGTCGGGGTGACCGTGGTGCTGACGTTCGTGGTGTTCATGGTGCTCGGCGGGCGCGCGTACTACGTCGCCGGCGTCTATGCGGTGGCCATGGCGGCCGGCGCCGTCTGGCTCACCCGCGATGGACCGCGACGCCGGCGGAAGATCGTCGCGGTCCCGCTGATCGCGGCATCTGCGGCCTTGGCCGGGTGGAGCCTGCCGTGGCAGCCGGAGCGCGATATCCCGCCGGTGTCGGCCGACGACGGAATGGCCACCTTGACGTACGGCAGATTCGGCTGGCCGGAGCTCGCCGAAGAAACCGCCGCCGCCTACCGCGATCTCACCGACGAAGAACGAGAATGGGCTGTCGTGATCGCCGAGTCATATTGGCAGGCAAGCGCACTGGACAACTACCCAGACGGGGATCTGCCTGCCGTGTACAGCCCCGGCCGGGGTTGGGGATATTTCGGGGCGCCGCCCGACGACGCGACGACCGTGCTCTACGTCGACCGGTACCCCGATACGGCTCGCGAGTTGTGTGCGCACGTGGACCCGGTCGGCCGGGCCGACGCGCGCCTGGGGATCCCGGGGGTGAGCCGTGACGTGACGATATGGAAGTGTGTCGATCCACGACAGCCGTGGTCGACGATCTGGCCTTCCCTTCGGCGCCTGTAA

Protein Sequence 

>Ms2315_MSMEG2315_protein
VLAGAAEASPGVLTVDHAANTKFGRAMTTTTTGADIETSPPRFARAGVGAVAAVSSIALLVFLDRYGYFGDELYFLSAGRRLSFGYADQGPALPLIAHVLDSVAPGSLFVLRLPAVLATAAAIVISAQIAREFGGGRGAQLLAAGGYATSPFLLVQGGQLATNSFDIPLWVLITWLLVRWARTRDDRLLLWAAVATAFALQIKWLVPILWICVGLSVLLVGPRELLRRRFLWVGAAGAALTTIPMLVWQAGNGWPQLAMGSVIAAENDTVGGRPAFVPLALFIAGLLGGVLLLCGVWALLRWEPLRPFRFVGVTVVLTFVVFMVLGGRAYYVAGVYAVAMAAGAVWLTRDGPRRRRKIVAVPLIAASAALAGWSLPWQPERDIPPVSADDGMATLTYGRFGWPELAEETAAAYRDLTDEEREWAVVIAESYWQASALDNYPDGDLPAVYSPGRGWGYFGAPPDDATTVLYVDRYPDTARELCAHVDPVGRADARLGIPGVSRDVTIWKCVDPRQPWSTIWPSLRRL

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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