MSMEG2314
ms2314
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 2394859 – 2396241
Vulnerability Index (VI):
M. tuberculosis homologs Rv1639c
M. abscessus homologs MAB2318c, MAB1022, MAB2451c
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG2310 MSMEG2311 MSMEG2312 nrdF2 MSMEG2314 MSMEG2315
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms2314_MSMEG2314_dna
TCGGCCTGACCGAGGACGTCAAGAAGTTCCTGCGCTACAACGCCAACAAGGCCCTGATGAACCTCGGCTACGAGGCGCTGTTCCCGCGCGACGAGACCGACGTCAACCCGGCGATCCTCTCGGCGCTGGCGCCCAACGCCGACGAGAACCACGACTTCTTCTCCGGCTCGGGGTCGAGCTACGTGATCGGCAAGGCCGTCAACACCGAAGACGAGGACTGGGACTTCTAGACCCGGTCCACGCCGTGCACGCAGGAACCCCGCAGTGAGCTGACAGCCTGCGCTGCTATCAAATAAACGATGCACCAGCTCATAGCGCAGATCCCGCTGACCGACGGCTGGTTTCCAGTCGTCGTCCAGCTGATCGGGGCACTGCTGCTGGGGGCTGCCGTCGGATGGCGCACGCGGCGGTGGCGGTTGCGGATCCTGCCTGCGCTGGTCGCCGCGGCCGCCGTGCTGGCCGGTGTGATGTATCGGTACATCGATTCGATCGGGGTGGCGGGCAACGCCGGACCGCCGCGGTTGTGGGTGTGGATCGCGCTGACCGTGTTGGCCTGTGGTGTCCTGGTGCTGGGCTGGATGAGTGCGCGGTGGTGGCGGCGGATCGTCTCCGTGGCGGCGGTCGGGGCGTGTCTGCTGGCCTGCGGGCTCACCCTCAATATGTGGGTCGGCTATTTCCCGACCGGGTACGCCATGTGGAATCAGCTCACCTCGGGTCCGCTGCCGGGCCAGACGGACCGGCTGACCGTCACCAAGATGCAGCTCGCCCACTTCCGGCCCGCCGGTGGGGTTCTGGTCCCGGTGACCATCGAGGCGGTATCAGGCTTCAGCCACCGCGAGGAACTCGTCTACCTGCCGCCGGCCTGGTTCGCCAGCAGTCCGCCGCCGGAGCTTCCGGCGGTGATGATGATCGGCTCGCAACTGAACACCCCGGCGGACTGGTTACGGGCGGGCAACGTGCAGCCGGTCATCGACCGGTTCGCCGCCGAGCACGGCGGGATGGCACCGGTCTTCGTCTTCGTCGACGCCACCGGCTCGTTCGCCAACGACACCGAGTGTGTCAACGGCGTGCGGGGCAACGCGGCCGATCACCTCGTCAAAGATGTTGTGCCGTATCTGGTCTCGAACTTCGGCGTGCGGCCGGATCGCGACGGCTGGGGCATCGCGGGATGGTCGATGGGCGGCACGTGCGCGGTGGATCTGACCCTGATGCATCCCGACGTCTTCCGGTCGTTCGTCGACATCGCCGGTGACCTGCGGCCCAACGCGGGGGACAAGGCACAGACGATCAGCCGACTGTGGGGTGGCGACGTCGCCTCCTGGGCCGCATACGATCCCGTCACCATCATGGGTCGGCACGGCCCGTACACCGGTCCGTCCGCCGATGTCACGGCGTGGTTCGAGGTGCCCGCGGCGCAGCGCGGCGCGGGCCCCGACCCGGCCAATCCGGAAGGGCAGGACGTCGCCGCGGTCACGCTGTGCGATGCGGCCAGAGCGGTCTCCATCGACTGTTCGGTGATCACCGAACCGGGGCGGCATGACTGGGTTTTCGCCAACACCGCGTTCGCCAGGGCCCTGCCATGGCTGGCCGGCCAACTGCACACGCCTGGCGTCGCGGCTGTGCCGCTGCCGGCGTCTACGTTGGGGCAGCAGCCCACAAACGTCCGGGCGGCCCCGCGCTAG

Protein Sequence 

>Ms2314_MSMEG2314_protein
MHQLIAQIPLTDGWFPVVVQLIGALLLGAAVGWRTRRWRLRILPALVAAAAVLAGVMYRYIDSIGVAGNAGPPRLWVWIALTVLACGVLVLGWMSARWWRRIVSVAAVGACLLACGLTLNMWVGYFPTGYAMWNQLTSGPLPGQTDRLTVTKMQLAHFRPAGGVLVPVTIEAVSGFSHREELVYLPPAWFASSPPPELPAVMMIGSQLNTPADWLRAGNVQPVIDRFAAEHGGMAPVFVFVDATGSFANDTECVNGVRGNAADHLVKDVVPYLVSNFGVRPDRDGWGIAGWSMGGTCAVDLTLMHPDVFRSFVDIAGDLRPNAGDKAQTISRLWGGDVASWAAYDPVTIMGRHGPYTGPSADVTAWFEVPAAQRGAGPDPANPEGQDVAAVTLCDAARAVSIDCSVITEPGRHDWVFANTAFARALPWLAGQLHTPGVAAVPLPASTLGQQPTNVRAAPR

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

You do not have permission to view notes.