MSMEG2317
ms2317
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 2399432 – 2400481
Vulnerability Index (VI):
M. tuberculosis homologs adhC, adhB, adh
M. abscessus homologs MAB3400, MAB2084, MAB4560, MAB0983c, MAB4388
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG2315 MSMEG2317 MSMEG2318 MSMEG2319
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms2317_MSMEG2317_dna
TCAGCGTCGAGGACGCGCAGGCGCTCACCGAAGCCGATCCCTACTCGCAGGCCGGCCTGGTGAGCTACGAGCGCGTCTCGTTCAACGGTTCGATCCGCGCACCCGGTCTCTAGACGGCCGACTCGGAGCGGACTCTCAGGCCCCTGACAGGGAGCACCGTCACAGTCGATATCGGGATTACCGCGCCGTCAATCTCAGTTGCACTCTGTTGTGCCGCGCGACGTGATGCGCGCGGCGGACACCCGTGAACTGGACTAACGTCCCGGGCAGTAATGAAGAATCGACGATAAGAGGTCTGTCATGAGTACCGTTTCCGCGTATGCCGCCACCTCGGCGACCGAACCACTGACCAAGACCACCATCACCCGTCGCGCCGTGGGTCCGCACGATGTTGCGTTCGACATCCACTTCGCAGGCATCTGTCACTCCGACATCCACACCGTCAAGGCCGAGTGGGGCGTCCCGAACTACCCCGTGGTCCCCGGTCACGAGATCGCCGGCGTGGTCACCGAGGTGGGCTCGGAGGTCACCAAGTACAAGGTCGGCGACCGCGTCGGCGTCGGCTGCTTCGTCGACTCCTGCCGAGAGTGCGACAACTGCAAGGCCGGCCTGGAGCAGTACTGCACCGGCACCGGCATGGTCGGCACCTACAACGCGATCGACCGCGACGGCACCCCGACCCACGGCGGTTACAGCGGCGCCATCGTGGTCGACGAGAACTACGTGCTGCGCATCCCCGACAGCCTTCCGCTCGACGCGGCCGCTCCCCTGCTGTGTGCGGGCATCACCACCTATTCCCCGCTGCGGCACTGGAATGCCGGCCCCGGCAAGAAGGTCGCCGTCATCGGGCTCGGCGGCCTCGGCCACGTGGCCGTCAAGCTCGCCAAGGCGATGGGCGCCGATGTCACGGTGCTCAGCCAGTCGCTGAAGAAGATGGAAGACGGCCTGCGCCTGGGCGCCTCGGCCTACTACGCGACGTCCGATCCGGAGACGTTCGACAAGCTCGCCGGGTCGTTCGACCTGATCCTCAACACCGTGTCGGCGAACCTGGACCTCGGTGCCTACCTGGGCCTGCTCAAGCTCGACGGCGCGCTCGTCGAACTCGGCCTGCCCGAGCACCCCATGGAGGTCCCGGCGTTCCCGCTGCTCGCTCAGCGACGCAACCTCACCGGCTCGATGATCGGCGGCATCCCCGAGACCCAGGAGATGCTCGACTTCTGCGCCGAACACGACGTCCGGCCGGAGATCGAGATCATCACCCCCGACTACATCAACGAGGCCTACGAGCGCGTCCTGGCCAGCGATGTGCGCTACCGCTTCGTGATCGACACCGCGTCGCTGCGTAGCTGA

Protein Sequence 

>Ms2317_MSMEG2317_protein
MSTVSAYAATSATEPLTKTTITRRAVGPHDVAFDIHFAGICHSDIHTVKAEWGVPNYPVVPGHEIAGVVTEVGSEVTKYKVGDRVGVGCFVDSCRECDNCKAGLEQYCTGTGMVGTYNAIDRDGTPTHGGYSGAIVVDENYVLRIPDSLPLDAAAPLLCAGITTYSPLRHWNAGPGKKVAVIGLGGLGHVAVKLAKAMGADVTVLSQSLKKMEDGLRLGASAYYATSDPETFDKLAGSFDLILNTVSANLDLGAYLGLLKLDGALVELGLPEHPMEVPAFPLLAQRRNLTGSMIGGIPETQEMLDFCAEHDVRPEIEIITPDYINEAYERVLASDVRYRFVIDTASLRS

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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