serB
ms2321
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 2404009 – 2405250
Vulnerability Index (VI):
M. tuberculosis homologs serB2, Rv3661
M. abscessus homologs MAB3388c, MAB0431c
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG2319 serB MSMEG2322 MSMEG2323 MSMEG2324 MSMEG2325 MSMEG2326
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms2321_serB_dna
TGTGGAACGTGTTCAAGAGCTGGCGTTACGGCGAGCCCGTCACGGTCGACGATCCGTGGGGCTACGGCAACTCCCTGGAGTGGGCCACCAGCTGCCCGCCGCCGCGGCACAACTTCACCGAGCTGCCGCGTATCCGGTCGGAGCGTCCGGCGTTCGAGCTGCACTACCCGCACATGGTCGAGCGGATGCGGGCCGAGGCCCACGTGGGTCGCGCCCACCATCCCGAGCTCGAGACCGCGGACAAGTCCAGCTGACGCCTTCGCGCCAACTGGGTGAACAACTGAGAAGGTGACCTGTAGATGAGCTCGGCACGCGAGCGCTCATCGCTACTGATCACCGTCACCGGTGTCGACCAGCCGGGCGTCACCTCGGCACTGTTCGAGGTGCTGTCCCGGCACAAGGTCGAGCTGCGCAACGTCGAGCAGGTCGTGATCCGCGGCCGGCTCACGTTGGGCGTTCTGGTGGCCGCGCCGTCCGACGTGGCCGACGGCGATGATCTGCGACGCGACGTCGAGGCCGCCATCCACGGCGTGGGTCTCGACGTCGCGATCGAACGCAGCGACGACCTGCCGGTGATGCGTGAGCCCTCAACCCACACGATCGTGGTGCTGGGCCGTCCGATCACCGCCGAGGCGTTCGGGGTGGTCGCCCGCGCGGTGGCCGATCTGGGCGTCAACATCGATTTCATCCGCGGCGTCTCCGACTACCCGGTGACGGGGCTGGAGCTGCGCGTGTCGGTCCCGGCGGGCGCGGCCTACGGGCAGTTGCAGCAGGCGCTCGCCACGGTCGCCGCGAACGAGGGCGTCGACATCGCGCTGGAGGACTACACGCTGTCACGACGGGCCAAGCGGCTCATCGTGTTCGACGTCGACTCGACCCTCATCCAGGGTGAGGTGATCGAGATGCTGGCCGAGCACGCCGGTGCCGCGGCAGCCGTCGCCGAGGTGACCGAGGCCGCGATGCGGGGTGAACTCGACTTCGCCGAGTCTTTGCACCGCCGGGTCGCGACGCTCGCCGGGCTGCCTGCCTCGGTACTCGACGAGGTCGCCGAGCAGTTGGAGCTCACACCGGGGGCGCGGACCACGATCCGCACCCTCCGCAGGCTGGGCTACTACTGCGGTGTGGTCTCGGGCGGATTCCGCCAGGTCATCGAACCGCTCGCGCACGAACTCATGCTCGACTACGTCGCGGCCAACGAACTGGAGATCGTCGACGGCAAGCTCACCGGACGCGTCGTCGGCGACGTCGTGGACCGGCCGGGCAAGGCCAAGGCGCTGCGGGACTTCGCCCAGCAGGTCGGCGTACCGATGGAGCAGACCGTCGCCGTCGGCGACGGCGCCAACGACATCGACATGCTGTCGGCCGCGGGCCTCGGGGTGGCGTTCAACGCCAAACCCGCGCTGCGTGAGGTGGCCGACGCGTCACTGAGCCATCCGTACCTGGACACCGTGCTGTTCATCCTGGGCATCACGCGCGGCGAGATCGAGGCCGCCGATGCGCTCGACGGTGTGGTGCGCCGCGTCGAGATCCCGGATTATTAG

Protein Sequence 

>Ms2321_SerB_protein
MSSARERSSLLITVTGVDQPGVTSALFEVLSRHKVELRNVEQVVIRGRLTLGVLVAAPSDVADGDDLRRDVEAAIHGVGLDVAIERSDDLPVMREPSTHTIVVLGRPITAEAFGVVARAVADLGVNIDFIRGVSDYPVTGLELRVSVPAGAAYGQLQQALATVAANEGVDIALEDYTLSRRAKRLIVFDVDSTLIQGEVIEMLAEHAGAAAAVAEVTEAAMRGELDFAESLHRRVATLAGLPASVLDEVAEQLELTPGARTTIRTLRRLGYYCGVVSGGFRQVIEPLAHELMLDYVAANELEIVDGKLTGRVVGDVVDRPGKAKALRDFAQQVGVPMEQTVAVGDGANDIDMLSAAGLGVAFNAKPALREVADASLSHPYLDTVLFILGITRGEIEAADALDGVVRRVEIPDY

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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