MSMEG2319
ms2319
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 2400954 – 2402027
Vulnerability Index (VI):
M. tuberculosis homologs fecB
M. abscessus homologs MAB3390
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG2317 MSMEG2318 MSMEG2319 serB
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms2319_MSMEG2319_dna
GCTTGTAGATCAAGTTCCCCTTGGGGCCCATACGTTCCGGAAACGGACGACGTGCCTCGAGTTCTCCGATTGGGGGCGCTTCGGCTACCAAGAGGTCCTCCAAAGATCGTCGGGAATACCCGCTAATTCGAATAAATCCTAGCGCTCTCCGCGCCGCGCGTGCCCGTGGGTCCTACAAACCGTCGTATTCGGCGTGCGGCCCCGGCGTGCGGCGTCTCGGGCACTGCGCTGACCTGCAGGAAACGCACAGGCAGCCGGGACGCGACGGCGCGGAAAGTTACTGAATGTTACCGTCGCCCGGTGCTGACCTTCCGACCGCTGGTGGGGACGGCGCTGATCGCCGCGGCCGCGTCACTGATCAGTGGCTGCGGTACCTCCGGCGAACAGCCCGTGACGCAGCCGTCCATGACGACCAGCGTGACCAAGATCGCCGATGCGGGTGTCCTCGGCAACCAGCGCAGGCCCGACGAATCGTGCGCACCCGAGCCCGTGGCGGCCGACCCGGCCCCGCGGCGTGTCCGCAACGCGACGGCCGACGGCGCCGACATCGCCGAGACCACCGAAGTCGCCGGCGACCCCCAGCGCATCGTCGTGTTGTCGGGCGACCAACTCGACGCGCTGTGCGCGCTGGGCCTGCAGTCGCGCATCGTCGCCGCGGCGCTGCCCGACGGTTCGGACGCGCAGCCGTCGTATTTGGGCACCGTCGTGCACGACGTCCCTCCCGCCGGTGACCGCGCAGCACCCGACGTCGCGGCGATCAGGGCCGCGGATCCGGACCTGATCCTCGGTTCGGCCGCGCTGACGCCCGGTGCGTTCGGTGAACTGTCGGACATCGCCCCGACGGTGTTCACCGGGACACCCGGCGCGGCCTGGCGCGACACGCTACGCGCCGTGGGCGCCGCGACCGGGCGCGCGGGCGCGGCCGACGATCTCATCGCCGGGTTCGAGGACGCCGCCCGCAAGACCGGTGAGGACAACGACGCGGCCCACTTCCAGGCGTCGGTGGTGCAGCTGACCGAGAACACCGTGCGGGTGTTCGGCGCCGACAACTTCCCGGGCGACGTGCTCGCGGCCGTGGGCCTGGATCGTCCTGCCGCACAACGGTTCACCGACAAGCCCTATGAGGAGATCCCGGCCGACAGCGACGACTTCTCGATCGCCGACGCCGACATCGTCTACGTGTCGTTCGCCTCACCGGCCGCGCGGGACAAGGCCGACGCGGTCCTCAAGGGTGACGCCTGGCGGAAACTGTCGGCCAACCGCGACAACCGGGTGTTCGTCGTCAACAACGAGGTGTGGCAGACCGGGCAGAACATCGTGGCCGCTCGCGGGATCCTGGACGACCTGCGCTGGGTCAACGCACCGATCAACTAG

Protein Sequence 

>Ms2319_MSMEG2319_protein
VLTFRPLVGTALIAAAASLISGCGTSGEQPVTQPSMTTSVTKIADAGVLGNQRRPDESCAPEPVAADPAPRRVRNATADGADIAETTEVAGDPQRIVVLSGDQLDALCALGLQSRIVAAALPDGSDAQPSYLGTVVHDVPPAGDRAAPDVAAIRAADPDLILGSAALTPGAFGELSDIAPTVFTGTPGAAWRDTLRAVGAATGRAGAADDLIAGFEDAARKTGEDNDAAHFQASVVQLTENTVRVFGADNFPGDVLAAVGLDRPAAQRFTDKPYEEIPADSDDFSIADADIVYVSFASPAARDKADAVLKGDAWRKLSANRDNRVFVVNNEVWQTGQNIVAARGILDDLRWVNAPIN

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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