MSMEG2326
ms2326
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 2407969 – 2408817
Vulnerability Index (VI):
M. tuberculosis homologs Rv3041c, Rv1687c, Rv1747, proV, Rv1458c, [+ 6 remaining orthologs]
M. abscessus homologs MAB3384c, MAB2461, MAB1502, MAB3698, MAB1655, [+ 14 remaining orthologs]
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 serB MSMEG2322 MSMEG2323 MSMEG2324 MSMEG2325 MSMEG2326 MSMEG2327 MSMEG2328 MSMEG2329 MSMEG2330
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms2326_MSMEG2326_dna
ACCGTGCTCTACATCGGCGCCGGTCTCGGTCCCGGGCCGCGCGACGGCCTGATGACCGGCCTCGTGGCGCGTACCGGGCTGTCGGTGCGACTCGTCCGCACGTGCATCGAGGCCACCGTGCTGGCCGTCGGATGGCTCATGGGCGGGACCGTCGGTGTGGGAACGGTCCTGTACGCCTTCGGGATCGGCCCGCTGGTGCAGTTGTTCCTCAGACTCACCCCGCGCCGCATCCTGTTCCACGATTTCGGCGCGCCCGGGCGTAACCGGGCGAGCGGCGAGGACATCACTACGATGAGCGGGTGCCCACAACCGGAGAAGACGCAGCCGACAACCCAGACCTGCTGATCGACTTCGCCAGGGTCACCCTGAGGCGCGGGGGCAACACCCTCGTCGGGCCCATCACCTGGGCTGTCGAACTCGACGAGCGCTGGGTCGTCATCGGTCCCAACGGCGCAGGCAAGACCTCGCTGTTGCGCATCGCCGCGGCGACCGAACACCCGTCGTCGGGAACCGCCTACGTACTGGGGGAGCGGCTGGGCCGCACCGACATGGCCGAACTGCGTTCGCGCGTCGGCCTGAGCAGCTCGGCTCTGTCGCAACGGATTCCCGACGACGAGATCGTCCGCGACCTCGTCGTGTCGGCCGGGTACGCGGTGCTCGGGCGGTGGCGCGAGCAGTACGACGACGTCGACTACGAGCAGGCCGTGAACATGCTCGAAAGCGTCGGCGCCGAGCACCTCGCCGAACGCCGGTACGGCACCCTGTCGGAGGGCGAACGCAAACGCGTCCTGATCGCCCGGTCGCTCATGACCGACCCGGAACTCCTGCTGCTCGACGAGCCCGCGGCCGGGCTCGACCTCGGCGGCCGCGAGGACCTCGTGGCCCGTCTCACCGACCTCGCCGCCGACCCCGATGCACCGGCCATGGTGCTCGTGACGCACCATGTCGAGGAGATCCCGGTCGGGTTCAGCCACGGCTTGATCCTGTCCGAGGGCAAGGTGGTGGCCTCCGGTCTGCTCACCGATGTGCTGACGTCCGAGAACCTGTCCAAGGCATTCGGCCAGGCCATCGCCCTCGAGGTGATCGACGGACGGTACTTCGCGCGCCGGGTGAGGAGCCGGGCAGCGCACAGGAGGCGAAATGACTGA

Protein Sequence 

>Ms2326_MSMEG2326_protein
VPTTGEDAADNPDLLIDFARVTLRRGGNTLVGPITWAVELDERWVVIGPNGAGKTSLLRIAAATEHPSSGTAYVLGERLGRTDMAELRSRVGLSSSALSQRIPDDEIVRDLVVSAGYAVLGRWREQYDDVDYEQAVNMLESVGAEHLAERRYGTLSEGERKRVLIARSLMTDPELLLLDEPAAGLDLGGREDLVARLTDLAADPDAPAMVLVTHHVEEIPVGFSHGLILSEGKVVASGLLTDVLTSENLSKAFGQAIALEVIDGRYFARRVRSRAAHRRRND

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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