MSMEG1005
ms1005
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1074818 – 1075633
Vulnerability Index (VI):
M. tuberculosis homologs Rv1403c, Rv1405c, menH, Rv3038c, Rv1377c, [+ 1 remaining orthologs]
M. abscessus homologs MAB3930c, MAB3381c, MAB0868c, MAB4613, MAB4018
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG1001 MSMEG1002 MSMEG1003 MSMEG1005 MSMEG1006 MSMEG1007 MSMEG1008 MSMEG1009
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1005_MSMEG1005_dna
TCAACTGCGAAGAGCCTGAAATGGGTACTGCCCAACAGCAGTTCCCGCACCACGAGCAGGGTCCAGCGTTCATCGAGCAGTTCCATGGCTTTGGCGACGGGGCAGAACTGGCCATAGGTCGACATGTGCGGCACCTTCCGGACAATTGCGCAACTGCGCACACCTGAGCACAAGTACACCGCGCAAACGTCGCCGAGCCAATACAGAATTTGAACCACAGGTAGTACAGATCTGTTACTGGATTCCTGTACCGGCGCGGCGGGACCATGACTGACACATGCCGAACCGAAGGAGTCACCATGGGCGTCGTCACCGTCGATCGAGAACTTGAGGCCAAACACCGGGCGCTGTGGGCGCTCGGGAACTACGGGGCGATCGCCGCCCATATCGTCGCACCGCTGGGACCCGTCCTCGTCGAGGCCTGCGGTATCGGACCCGGGGACCGGGTGCTCGACATCGCGGCAGGCACGGGCAACGCCTCGATCCCCGCCGCGCTGGCAGGCGCTCAGGTCACCGCGAGCGACCTGTGCCCGCAACTGGTCGACGAGGGCGCACACGAGTCCGCCGAGCGAGGCGTGGACATCACGTGGAAAGAGGCCAACGCCGAGGCGCTGCCGTTCTCCGACGGCGAGTTCGACGTCGTGATGTCCTGCATCGGCGTGATGTTCGCGCCGCATCACGACCAGTCCGCTCGGGAGCTGTTGCGGGTCACGCGTTCCGGTGGACGGATCGGTCTGATCAGCTGGACCCCAGAGGGTTTCATCGGGCAGCTGTTCGCGACCATGAAGCCGTTCGTTCCCGCGCCGCCGCCGGGCGTGTCGCCACCGCCGTTGTGGGGCAACGCCGATCATGTCCGAACGCTGCTCGGCGATGGGATCGAGGACTTCGAGACGCAGCGTCGCTCGTTGACGGTGGACATGTTCGCCGACGGAGCCGCCTTCCGCGACTTCTTCAAGGCCAACTACGGTCCCACCATCGCGGCCTACCGCGCCGTCGGTGACGACGCCGAACGCACCGCGGCGCTCGACGAGGCCATCGCCTTGCTGGGGGACCGATATCTCGATTCCGGTGCCATGCAGTGGGAGTACTTGGTGGTGACTGCACACAAACGCTGA

Protein Sequence 

>Ms1005_MSMEG1005_protein
MGVVTVDRELEAKHRALWALGNYGAIAAHIVAPLGPVLVEACGIGPGDRVLDIAAGTGNASIPAALAGAQVTASDLCPQLVDEGAHESAERGVDITWKEANAEALPFSDGEFDVVMSCIGVMFAPHHDQSARELLRVTRSGGRIGLISWTPEGFIGQLFATMKPFVPAPPPGVSPPPLWGNADHVRTLLGDGIEDFETQRRSLTVDMFADGAAFRDFFKANYGPTIAAYRAVGDDAERTAALDEAIALLGDRYLDSGAMQWEYLVVTAHKR

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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