MSMEG1009
ms1009
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1078286 – 1079770
Vulnerability Index (VI):
M. tuberculosis homologs cyp136
M. abscessus homologs MAB3423, MAB2078, MAB2151c
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG1005 MSMEG1006 MSMEG1007 MSMEG1008 MSMEG1009 MSMEG1010 MSMEG1011 MSMEG1012
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1009_MSMEG1009_dna
GCTCACTGATCGTGCTCACCGAGATGTCCGCGAACGGCTGTTCCTCGAGGAGTTCGCGCACGGCGGCGACGATGGCCTCCCGTTGCCGGTCGCCCCTGGAGCGACGGGCCTGCGCGGCGGTGGCGCCGGCAGAACCGTTGCTGCCCTGCGGTACGGATTCGGCGGTCATGGGTTTAAACCTTGGCACCCGCGACGCGCCAAATCAAAACTTGACATGCGTCAAGTATGACATCCAAGATGAGTGTCACAAGTGACGTCCACCACAGACTTGCAACGTCAGCAACGTCAGGAGCGCGATACATGCCCACCACCATCAGTACTCCCCGCTATCTGTTGGATCAGGCACGGCGCCGATTCACGCCCACGCCCAACACCATCCCCGGCATGGGAGCCATCGAGAAGCGGCTGAAGCGCAAGCAGTGGGACCAGTTCGTGTTCTCCACCCCGCCCGCAGGCAGCGGTCTCAAGCCGATCATGGGCGACTCCGGCCTGCCGGTCCTCGGGCACATGATCGAGATCTTCCGCGGCGGCCCCGACTTCATCCTGGAGCAATACCGCCGCAACGGCCCGATCCACTACGCCTACTCACCTGCGTTGTCGTCGGTGATGGCGCTGGGCCCGGACGCCACCCAGACGGTCTTCTCGAACCGCAACAAGGACTACTCGCAGCGTGCGTGGGATCCGGTGATCGGGCCGTTCTTCGAAGGTGGCCTGATGCTGCTCGACTTCGACGAGCACATGTACCACCGCCGGATCATGCAGGACGCGTTCACCCGCTCGCGGCTCACCGGGTACATCCCGCACATCGACTCGGTCGCGTCGCAGGTCCTGGCCAACGACTGGGTGTCCGACGATCCGCGGTTCCTGTTCTATCCGGCCATCAAGGAACTGACGCTCGACATCGCCTCCGAGGTGTTCATGGGCGTCCCGGCCGGCACCGACAAGAAGCTCGTCACGACCGTGAACCACGCGTTCACCACCACCACGCGCGCGGGCAACGCGATCGTGCGCACGCCGGTCCCGCCGTTGAAGTGGTGGCGCGGCATCCAGGCGCGCAAGACACTCGAGGACTACTTCCTCAGCCGCATCGACGAGAAGCGCCGCGCCGAGAGCACCGACATGTTCAGCGTGCTGTGCCACTCGGCCGACGAGGACGGCCAGACCTTCACCGACGACCAGATCGTCAGCCACATGATCTTCCTCATGATGGCCGCACACGACACGTCGACGTCGACCATGACCACCATGGCCTACCACCTGGCGGCCAATCCCGAGTGGCAGGACCGGCTGCGTGACGAGTCCGAGCGCATCGGCGACGGCCCGCTCGACATCGAGGCGCTGGAGAAGCTGGAGACCTACGACCTGGTGATCAACGAGGCGCTGCGGATGATGACGCCGCTGCCCTTCAACTTCCGCCAGGCCGTGCGCGACACCGAACTGCTGGGTTACTTCATCCCGGCCGGCACCAACGTGGTCACCTGGCCGTCGATCAACCACCGGCTGCCCGAACTGTGGACCGATCCGGAGAAGTTCGACCCGGAGCGCTTCGCCGAGCCGCGCAGCGAGCACAAGAAGCACCGCTACGCGTTCGCACCGTTCGGTGGCGGCGCCCACAAGTGCATCGGCATGGTGTTCGGCCAGCTGGAGATCAAGACCGTCATGCACCGCCTGCTGCGCCAGTACCGCCTGGAGCTGCCGCGTCCGGGTTACACGCCGCGCTACGACTACGGCGGCATGCCGGTGCCGATCGACGGGATGCCGATCGTGCTGCGTCCGCTGCGCTGA

Protein Sequence 

>Ms1009_MSMEG1009_protein
MPTTISTPRYLLDQARRRFTPTPNTIPGMGAIEKRLKRKQWDQFVFSTPPAGSGLKPIMGDSGLPVLGHMIEIFRGGPDFILEQYRRNGPIHYAYSPALSSVMALGPDATQTVFSNRNKDYSQRAWDPVIGPFFEGGLMLLDFDEHMYHRRIMQDAFTRSRLTGYIPHIDSVASQVLANDWVSDDPRFLFYPAIKELTLDIASEVFMGVPAGTDKKLVTTVNHAFTTTTRAGNAIVRTPVPPLKWWRGIQARKTLEDYFLSRIDEKRRAESTDMFSVLCHSADEDGQTFTDDQIVSHMIFLMMAAHDTSTSTMTTMAYHLAANPEWQDRLRDESERIGDGPLDIEALEKLETYDLVINEALRMMTPLPFNFRQAVRDTELLGYFIPAGTNVVTWPSINHRLPELWTDPEKFDPERFAEPRSEHKKHRYAFAPFGGGAHKCIGMVFGQLEIKTVMHRLLRQYRLELPRPGYTPRYDYGGMPVPIDGMPIVLRPLR

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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