MSMEG1050
ms1050
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1118097 – 1119260
Vulnerability Index (VI):
M. tuberculosis homologs Rv3037c
M. abscessus homologs MAB3380c
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG1046 MSMEG1047 MSMEG1048 MSMEG1049 MSMEG1050 MSMEG1051 MSMEG1052 MSMEG1053 MSMEG1054
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1050_MSMEG1050_dna
GCCGTCGTCGACCTGCACACGTTCGATCCGGCGGACCTGGAGCGCATGGCCACCAACGCCGGTGCGGTCGAGGTGCGCACCGCCAGCGAGGAATTCACCGCCGCCATGCTGGGCTGGCCGGTCCGCACGTTCGAGGCCGCGGTGCCGCCGGGCCGTCTGGGCTGGGGCTGGGCCAAGTTCGCGTTCAACAGCTGGACCACGCTGAGCTGGGTGGACGCCAACGTCTGGCGCAAGGTCGTGCCGAAGGGCTGGTTCTACAACGTCATGGTCACGGGGGTCAAACCCTCCTGAGCCCTGGGGTGACCTTCACGGTCGACGACGTCGCGTATCTGCGCTCGGCGGCAGGCAGGCAGGCGCTCGACGAGGCCGGGAAACTGGCCCTGTCGGGCGCCCGTCTGGTCAACGACATCGCCGCGCTGCGAGCGGCTTTCGGTGACCGGGCGGCCGTGCTGGCCGAGACCGTGCAGTTGCGCCGCCGCGCCGCGGCCAAGTTCGCCGACCCGTCGGACTGGCTGTTCACCGACGAAGCGTTGCAGCAGGCCACCGCGGCGCCGGTCGCGGCACACCGGGCCGCGCGACTCGCGGGTGCGACGGTTCACGATGCCACCTGCTCGATCGGCGGTGAGCTTGTCGCGCTTCGTGATTCGGCTGACCATGTGGTGGGCAGTGACCTGGATCCGGTGCGGGTGGCGATGGCCGCGGGCAACGTGCCCGACGTCGAGGTGTGCCGTGCCGACGCGCTGCGGCCCATCACGCGCGACGCCGTCGTGATCCTGGACCCCGCGCGGCGTGCGGGCGGCAGGCGGCGGTTCGACCCGCGTGCCTACACCCCGGCCCTCGACGCGGTGTTCGACGTGTACCGGGATCGCGACATGGTCGTGAAATGCGCTCCCGGAATCGATTTCGCCGAGATCGAACGCATGGGGTTCACCGGTGAGATCGAGGTGACCTCGGTGGGCGGGGGAGTGCGAGAGGCGTGCCTGTGGTCACCGGCGCTCGCCGGTGCCGGGGTGAGAAGGCGGGCCACCGTGCTGGACCGCGGCGAGCAGATCACCGACACCGAACCCGACGACTGCGCCGTCGCACCCGCCGGTCGGTGGATCGTCGACCCCGACGGGGCCGTCGTACGCGCAGGCCTGGTGCGCCACTACGCGGCCAGGCACGGGCTGTGGCAACTCGACCCCGACATCGCGTACCTCTCCGGTGACCGGTTGCCCGACGGGGTCCGCGGATTCGAGGTGCTCGAGGAGCTCGGCTACCACGAACGGCGTTTGCGGGCGGCACTTGCGGCACGGTCCGCCGGTGCGGTAGAGATACTGGTCCGCGGGGTCAATGTGGATCCCGACGTACTGCGAACGCGGTTACGGCTGCGCGGATCCAAGCAACTCACGGTGGTCATCACGCGGCTGGGGTCGGGATCGGCGAGCCGGGCGACGGCGTACATTTGCCGTCCCTCGCGATGA

Protein Sequence 

>Ms1050_MSMEG1050_protein
VTFTVDDVAYLRSAAGRQALDEAGKLALSGARLVNDIAALRAAFGDRAAVLAETVQLRRRAAAKFADPSDWLFTDEALQQATAAPVAAHRAARLAGATVHDATCSIGGELVALRDSADHVVGSDLDPVRVAMAAGNVPDVEVCRADALRPITRDAVVILDPARRAGGRRRFDPRAYTPALDAVFDVYRDRDMVVKCAPGIDFAEIERMGFTGEIEVTSVGGGVREACLWSPALAGAGVRRRATVLDRGEQITDTEPDDCAVAPAGRWIVDPDGAVVRAGLVRHYAARHGLWQLDPDIAYLSGDRLPDGVRGFEVLEELGYHERRLRAALAARSAGAVEILVRGVNVDPDVLRTRLRLRGSKQLTVVITRLGSGSASRATAYICRPSR

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

You do not have permission to view notes.