MSMEG1049
ms1049
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1117108 – 1118088
Vulnerability Index (VI):
M. tuberculosis homologs Rv3038c, Rv2952, Rv1523
M. abscessus homologs MAB3381c, MAB4018, MAB4799c, MAB0868c, MAB2257, [+ 6 remaining orthologs]
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG1045 MSMEG1046 MSMEG1047 MSMEG1048 MSMEG1049 MSMEG1050 MSMEG1051 MSMEG1052
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1049_MSMEG1049_dna
GGTACGCCTGGCGGACGCCATCGGGACCAGCAAGGCCAAGGAGCTCGTGTTCAGCGGCCGGTTCGTCGGCGCCGAGGAAGCGCTCGAGATCGGCCTGGTCGACGAGATGGTGGCACCCGACCACGTCTACGAGGCCGCGCTCGCGTGGGCCCGCCGGTTCTCCGACCATCCGGTCGACGTGCTGGCCGCCGCGAAAGCCTCCCTCAACGGGCCGGTCAACTGGCGGGGCCCCCGCCCGACCGATCGGATGGTGGACCGGCCCTGACCGGGACACCGGGGCGGCCATTAGGCTGCCCTGCATGACGGAAATCAGGGACGCCGCCGACCCGGCTCCGAACCCGCACGCCACGGCCGAAGAGGTCGAAGCCGCGATGCACGACAGCAAGCTGGCTCAGGTCCTCTACCACGACTGGGAGGCCGAGACCTACGACGAGAAGTGGTCGATCTCGTACGACCAGCGCTGCATCGACTACGCGCGCGGCCGGTTCGACGCCATCGTGCCCGAGGACGAGCAGCGCAAACTGCCGTACGACCGGGCCCTCGAGCTGGGCTGCGGCACCGGGTTCTTCCTGCTCAACCTCATCCAGTCCGGCGTGGCGCGTCGCGGTTCGGTCACCGACCTGTCGCCCGGCATGGTCAAGGTGGCCACCCGCAACGGCCAGTCGCTGGGCCTCGACATCGACGGCCGCGTCGCCGACGCCGAAGGCATCCCGTACGAGGACGACACGTTCGACCTGGTCGTCGGGCATGCTGTGCTGCACCACATCCCCGACGTCGAACTGTCGCTGCGCGAGGTCGTACGCATCCTCAAGCCGGGCGGACGGTTCGTGTTCGCCGGCGAACCCACCACGGTGGGCAACCGGTACGCCCGCGAGCTGTCGACCCTGACGTGGCACGCGACCACGAACCTGACCAAGCTGCCGTTCCTGAGCGGCTGGCGGCGGCCCCAGGAAGAACTCGACGAGTCCTCACGCGCGGCCGCCCTTGAGGCCGTCGTCGACCTGCACACGTTCGATCCGGCGGACCTGGAGCGCATGGCCACCAACGCCGGTGCGGTCGAGGTGCGCACCGCCAGCGAGGAATTCACCGCCGCCATGCTGGGCTGGCCGGTCCGCACGTTCGAGGCCGCGGTGCCGCCGGGCCGTCTGGGCTGGGGCTGGGCCAAGTTCGCGTTCAACAGCTGGACCACGCTGAGCTGGGTGGACGCCAACGTCTGGCGCAAGGTCGTGCCGAAGGGCTGGTTCTACAACGTCATGGTCACGGGGGTCAAACCCTCCTGA

Protein Sequence 

>Ms1049_MSMEG1049_protein
MTEIRDAADPAPNPHATAEEVEAAMHDSKLAQVLYHDWEAETYDEKWSISYDQRCIDYARGRFDAIVPEDEQRKLPYDRALELGCGTGFFLLNLIQSGVARRGSVTDLSPGMVKVATRNGQSLGLDIDGRVADAEGIPYEDDTFDLVVGHAVLHHIPDVELSLREVVRILKPGGRFVFAGEPTTVGNRYARELSTLTWHATTNLTKLPFLSGWRRPQEELDESSRAAALEAVVDLHTFDPADLERMATNAGAVEVRTASEEFTAAMLGWPVRTFEAAVPPGRLGWGWAKFAFNSWTTLSWVDANVWRKVVPKGWFYNVMVTGVKPS

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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