MSMEG1046
ms1046
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1114707 – 1115555
Vulnerability Index (VI):
M. tuberculosis homologs Rv3041c, Rv1687c, Rv1747, proV, Rv1458c, [+ 6 remaining orthologs]
M. abscessus homologs MAB3384c, MAB2461, MAB1502, MAB3698, MAB1655, [+ 14 remaining orthologs]
 +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon TSS Legend ? Ju, 2024 (4) Li, 2017 (5) (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 (4) PMID: 38418874 (5) PMID: 29326668 serB MSMEG1042 MSMEG1043 MSMEG1044 MSMEG1045 MSMEG1046 MSMEG1047 MSMEG1048 MSMEG1049 MSMEG1050
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1046_MSMEG1046_dna
ACCGTGCTCTACATCGGCGCCGGTCTCGGTCCCGGGCCGCGCGACGGCCTGATGACCGGCCTCGTGGCGCGTACCGGGCTGTCGGTGCGACTCGTCCGCACGTGCATCGAGGCCACCGTGCTGGCCGTCGGATGGCTCATGGGCGGGACCGTCGGTGTGGGAACGGTCCTGTACGCCTTCGGGATCGGCCCGCTGGTGCAGTTGTTCCTCAGACTCACCCCGCGCCGCATCCTGTTCCACGATTTCGGCGCGCCCGGGCGTAACCGGGCGAGCGGCGAGGACATCACTACGATGAGCGGGTGCCCACAACCGGAGAAGACGCAGCCGACAACCCAGACCTGCTGATCGACTTCGCCAGGGTCACCCTGAGGCGCGGGGGCAACACCCTCGTCGGGCCCATCACCTGGGCTGTCGAACTCGACGAGCGCTGGGTCGTCATCGGTCCCAACGGCGCAGGCAAGACCTCGCTGTTGCGCATCGCCGCGGCGACCGAACACCCGTCGTCGGGAACCGCCTACGTACTGGGGGAGCGGCTGGGCCGCACCGACATGGCCGAACTGCGTTCGCGCGTCGGCCTGAGCAGCTCGGCTCTGTCGCAACGGATTCCCGACGACGAGATCGTCCGCGACCTCGTCGTGTCGGCCGGGTACGCGGTGCTCGGGCGGTGGCGCGAGCAGTACGACGACGTCGACTACGAGCAGGCCGTGAACATGCTCGAAAGCGTCGGCGCCGAGCACCTCGCCGAACGCCGGTACGGCACCCTGTCGGAGGGCGAACGCAAACGCGTCCTGATCGCCCGGTCGCTCATGACCGACCCGGAACTCCTGCTGCTCGACGAGCCCGCGGCCGGGCTCGACCTCGGCGGCCGCGAGGACCTCGTGGCCCGTCTCACCGACCTCGCCGCCGACCCCGATGCACCGGCCATGGTGCTCGTGACGCACCATGTCGAGGAGATCCCGGTCGGGTTCAGCCACGGCTTGATCCTGTCCGAGGGCAAGGTGGTGGCCTCCGGTCTGCTCACCGATGTGCTGACGTCCGAGAACCTGTCCAAGGCATTCGGCCAGGCCATCGCCCTCGAGGTGATCGACGGACGGTACTTCGCGCGCCGGGTGAGGAGCCGGGCAGCGCACAGGAGGCGAAATGACTGA

Protein Sequence 

>Ms1046_MSMEG1046_protein
VPTTGEDAADNPDLLIDFARVTLRRGGNTLVGPITWAVELDERWVVIGPNGAGKTSLLRIAAATEHPSSGTAYVLGERLGRTDMAELRSRVGLSSSALSQRIPDDEIVRDLVVSAGYAVLGRWREQYDDVDYEQAVNMLESVGAEHLAERRYGTLSEGERKRVLIARSLMTDPELLLLDEPAAGLDLGGREDLVARLTDLAADPDAPAMVLVTHHVEEIPVGFSHGLILSEGKVVASGLLTDVLTSENLSKAFGQAIALEVIDGRYFARRVRSRAAHRRRND

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Non Essential in vitro TnSeq [Dragset et al. (2019)]

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