MSMEG2291
ms2291
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 2373847 – 2374710
Vulnerability Index (VI):
M. tuberculosis homologs Rv3057c, Rv0851c, Rv3085, Rv2766c, Rv0765c, [+ 17 remaining orthologs]
M. abscessus homologs MAB3420c, MAB4680c, MAB0090c, MAB3919c, MAB4019c, [+ 37 remaining orthologs]
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG2288 MSMEG2289 MSMEG2290 MSMEG2291 MSMEG2292 MSMEG2293 dinB
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms2291_MSMEG2291_dna
ACCGTCGCGCAGAACACCGACGCGCAGATCCGCGACATCATGAACGACTTCGAGGACGCCACGATCGCCAAGATCGTCGGCGTCATCGAACAGGACACCGGAGCCCGGCCGATCTCCGACGATCTGCCCGCACTGGTGCGCACCCTGACCGCGACCACGGCGATGACACTGTCGCGTGACGCCGGGTTCGTGGGCCGTGACGCCGATCCCGCGCGTGCCGTCGAGATCGTCGAACGCCTGTGGCTCAGCGCGCTGTGGGGTGGCCTGCCGGAGTAGATCTCCCCGGTAAGGTCACCGCTATGGCGCAGGGGAGCGACTTCGCGGGCAAGAGATGTTTCGTGACCGGGGCGGCCAGCGGCATCGGCCGCGCCACGGCGCTGGCGCTCGCCGCGGCGGGCGCCGAGCTCTACCTGACCGACCGCGACGCCGACGGGCTTGTGCAGACCGTCGCCGATGCGCGCGCGCTCGGCGCCGAGGTGCCTGCGCACCGCGCGCTCGACATCTCCGACTACGACCAAGTGCGCGAGTTCGCCAAGGACATCCACGCCGCGCACGGGTCGATGGACGTCGTGATGAACATCGCGGGCGTGTCCGCGTGGGGCACCGTCGACCGGCTCAGTCACCAGCAGTGGCGGTCGATGGTCGACATCAACCTCATGGGGCCCATCCACGTCATCGAGGAGTTCATCCCGCCGATGATCGAGGCGCGCCGCGGCGGGCACCTGGTCAACGTGTCCTCGGCGGCCGGTCTGGTCGCCCTGCCGTGGCACGGTGCCTACAGCGCAAGCAAATTCGGCCTGCGCGGCGTGAGCGAGGTGCTGCGATTCGACCTGGCGCGACACCGCATCGGGGTGTCGGTGGTGGTGCCCGGCGCCGTGAAGACCGGCCTGGTGCAGACCGTCGAGATCGCCGGCGTCGACCGCGAGGACCCCGACGTCAAGAAGTGGGTGGATCGCTTTGCCGGACATGCGATCTCACCTGAGAAGGCCGCCGCGAAGATCCTGGCGGGGGTACGACGCAACCGGTTTTTGATCTACACCTCGGCCGACATCCGCGCGCTGTACACGTTCAAGCGCGTGGCCTGGTGGCCCTACAGCGTGGCGATGCGCCAGGTGAACGTGCTGTTCACCCGCGCTCTGCGCTCCGGCACATCGCCACGCTGA

Protein Sequence 

>Ms2291_MSMEG2291_protein
MAQGSDFAGKRCFVTGAASGIGRATALALAAAGAELYLTDRDADGLVQTVADARALGAEVPAHRALDISDYDQVREFAKDIHAAHGSMDVVMNIAGVSAWGTVDRLSHQQWRSMVDINLMGPIHVIEEFIPPMIEARRGGHLVNVSSAAGLVALPWHGAYSASKFGLRGVSEVLRFDLARHRIGVSVVVPGAVKTGLVQTVEIAGVDREDPDVKKWVDRFAGHAISPEKAAAKILAGVRRNRFLIYTSADIRALYTFKRVAWWPYSVAMRQVNVLFTRALRSGTSPR

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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