MSMEG2310
ms2310
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 2391489 – 2392988
Vulnerability Index (VI):
M. tuberculosis homologs Rv3049c, Rv1393c, Rv0892, Rv0943c
M. abscessus homologs MAB3920c, MAB2074, MAB2073, MAB4476c, MAB0522c, [+ 13 remaining orthologs]
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG2307 MSMEG2308 MSMEG2309 MSMEG2310 MSMEG2311 MSMEG2312 nrdF2 MSMEG2314
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms2310_MSMEG2310_dna
CACGGACTGGTGGCTGGGCAGTAAAGAGGACAGCCCGCGCCGCATGCCCGCAGACGAGTTCGTCAACCACCTGACCACGATCATGGTCGGCTCCATCAACGGCACCTGCGAGCTGCTGGGCATCCGGATCGACCCGGATCTGCCCCTGCACGAGGGTGTGCAGCGCCGCGAACGCGCCAGTTAGTCACACCAGTCACATCGCGCAACTCTCGGGGTGGTCCGAGCGTTGACAGGTCAGCCACCGCGCCGGACACTGGCAAATATCCGGTACCGGCGTTCCCAGGAAAGGACCTGAAACCATGACGGCTGCCGACCAGCAACCCATCCGGACCCGCGCCCTGGTGATCGGCACCGGGTTCTCCGGGCTGGGCATGGCCATCGAACTGCAGCGCCGTGGCGTCGACTTCCTGATTCTGGAGAAGGCCGACGAGATCGGCGGCACCTGGCGCGACAACACCTACCCGGGATGCGCGTGCGACATCCCGTCGCACATGTACTCGTTCTCGTTCGAGCCCAAGGCCGACTGGAAGCACATGTGGTCCTTCCAGCCCGAGATCCAGGACTACCTGCTGGGCGTGACGGCCAAATACGGACTGCGCCGTCACATCCACTTCAACTCGCACGTCGACCGCGCGCACTGGGACGACGAGGAACTGCGCTGGCATGTGTTCACCAAGACCGGCCAGGAGTACATCGCCCAGTTCCTGGTGTCCGGCGCAGGCGGTCTGCACATCCCGCAGATCCCGGACATCGAAGGCCGGGAGTCGTTCGCGGGCGCGGCTTTTCACTCGGCGCAGTGGGACCACAGCGTCGATTTGCGCGGTAAGCGCGTCGCGGTGATCGGCACCGGCGCCAGTGCCATCCAGATCGTGCCGGAGATCGTCAAGGACGTCGCCGAACTGCACCTGTACCAGCGCACCCCGGCCTGGGTGATGCCACGCGTCAACAACGCGTTCCCGCAATGGCTGCGCAACGTCTTCAGCTACGTCCCCGGCACCCGCGCGCTGCTGCGCGCGGCCATCTACTGGATCCATGAGGGCGTCGGCTTCGCGATGACCAAGGAGCCGCGCCTGCTCAAGATCGGCGAGTGGATGGGCCGCTACAACATCAACCGCAGCATCAAGGACCCCGAGCTGCGGCGTAAGCTCACGCCGAGCTACCGCGCCGGGTGCAAGCGAATCCTCAACTCCGACACCTACTATCGCGGGATCGCCGACCCCAAGACCCAGGTGATCACCGAGGGCATCGCCCGGATGACGCCGACCGGCATCGTCACCAACGACGGCGTCGAGCATCCCGTCGACATCGTCGTCTACGCCACGGGCTTCCACGTGACCGACTCCTACACCTACGTCGACATCAAGGGTGCGGGCGGCGAAGACCTGGTCGACCGCTGGAACCGCGAGGGCATCCAGGCCCACCGCGGCGTCGCCGTCGCCGGCATGCCGAACCTGTTCTTCCTGCTGGGGCCGAACACCGCGCTGGGCCACAACTCGGTGGTGTTCATGATCGAGCAGCAGATTCGCTACGTCGGGCAGGCCATCGCCGCCGTCGACAAGGCGGGCGCGGCCGCGTTGGCGCCGACCCGGCGCGCGCAGGACGCGTTCAACGCCGAGTTGCAGCGGGATTTGTCCGGCACGGTGTTCAACACGGGCGGTTGCAAGAGCTGGTACCTCGACGAGCACGGCGTCAACCGGACGCTGTGGAGCGGCATGACATGGCAGTACTGGAAGGCGCTGCGCCGCCTCGATCCGTCGGAGTTCGAGTTCCTCGACCAGCGGGTTCTCGCGCGATCCTAG

Protein Sequence 

>Ms2310_MSMEG2310_protein
MTAADQQPIRTRALVIGTGFSGLGMAIELQRRGVDFLILEKADEIGGTWRDNTYPGCACDIPSHMYSFSFEPKADWKHMWSFQPEIQDYLLGVTAKYGLRRHIHFNSHVDRAHWDDEELRWHVFTKTGQEYIAQFLVSGAGGLHIPQIPDIEGRESFAGAAFHSAQWDHSVDLRGKRVAVIGTGASAIQIVPEIVKDVAELHLYQRTPAWVMPRVNNAFPQWLRNVFSYVPGTRALLRAAIYWIHEGVGFAMTKEPRLLKIGEWMGRYNINRSIKDPELRRKLTPSYRAGCKRILNSDTYYRGIADPKTQVITEGIARMTPTGIVTNDGVEHPVDIVVYATGFHVTDSYTYVDIKGAGGEDLVDRWNREGIQAHRGVAVAGMPNLFFLLGPNTALGHNSVVFMIEQQIRYVGQAIAAVDKAGAAALAPTRRAQDAFNAELQRDLSGTVFNTGGCKSWYLDEHGVNRTLWSGMTWQYWKALRRLDPSEFEFLDQRVLARS

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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