dinB
ms1014
-
M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [Phyre2] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1084283 – 1085353
Vulnerability Index (VI):
M. tuberculosis homologs dinP, dinX
M. abscessus homologs MAB2702c, MAB0977c
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG1011 MSMEG1012 MSMEG1013 dinB MSMEG1015 MSMEG1016 MSMEG1017 MSMEG1019
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1014_dinB_dna
GTCTGCTCGCCTACGGCCGCGAACGGATGAAGTTCGTCCGCGAGCACCACGCACTGCTCTCCGACGCCGCGCGCGATCCGCAGGCACGCTTCGGCGGGCCGGACACGCTGCACCGGTCCCACGTCCGGATGCTGCTGCAGGCCGCGGGGACCACGGGCGACCTCGACGCACAGGCCGACGCGCTCGTCGCGCTGCTCGACGCCGACTACGTCGCCTACCAACTGGAACGCGGACGCAGCTGCGAGGTCCAGGCCGCCGCCTGGGCCGACACCGCACGTAAGTTGTGTGGCCACTAGCGCGATGACCAAATGGGTGCTCCACGTCGATCTGGACCAGTTCCTGGCTTCGGTGGAGTTGCGCCGCCGCCCCGACCTGCGGGGGCAACCGGTCATCGTGGGCGGCAGCGGTGACCCGTCCGAACCACGCAAGGTCGTGACGTGTGCGTCGTACGAGGCGCGCGAGTTCGGCGTCCACGCCGGGATGCCGCTGCGGGCCGCGGCACGACGCTGCCCCGACGCCACCTTCCTGCCGTCGGATCCCGCGGCGTACGACGAGGCGTCCGAACAGGTCATGGGACTGCTGCGCGACCTGGGCCACCCGTTGGAGGTGTGGGGCTGGGACGAGGCGTATCTGGGCGCCGACCTCCCCGACGAGTCCGACCCGGTGGAGGTGGCCGAGCGCATCCGCACCGTGGTCGCGGCCGAGACGGGACTGTCCTGTTCGGTCGGGATCAGTGACAACAAGCAGCGCGCCAAGGTCGCCACCGGATTCGCCAAGCCCGCCGGGATCTACGTGCTGACCGAGGCGAACTGGATGACGGTGATGGGCGATCGCCCGCCCGACGCGCTGTGGGGCGTCGGGCCGAAGACGACGAAGAAGCTTGCGGCGATGGGCATCACGACCGTCGCCGATCTCGCCGTGACCGACCCGTCGGTGCTGACCACGGCGTTCGGCCCGAGCACCGGGTTGTGGCTCCTGCTGCTGGCCAAGGGCGGTGGCGACACCGAGGTCAGCTCCGAACCGTGGGTCCCCCGCTCGCGCAGTCACGTCGTGACGTTCCCGCAGGACCTGACCGAACGCCGCGAGATGGACTCGGCGGTGCGCGATCTCGCGTTGCAGACGCTGGCCGAGATCGTCGAACAGGGCCGCATCGTCACGCGCGTCGCGGTCACGGTGCGCACCAGCACCTTCTACACCCGCACCAAGATCCGCAAGCTTCCCGCGCCGAGCACCGACGCCGGTCAGATCGTCGACACGGCGCTGGCGGTGCTGGATCAGTTCGAACTCGACCGTCCGGTCCGGTTGCTCGGGGTGCGCCTGGAACTCGCGATGGATGACGTGCCCCGCCCCGCTGTCACTGCAGGCACCTAA

Protein Sequence 

>Ms1014_DinB_protein
MTKWVLHVDLDQFLASVELRRRPDLRGQPVIVGGSGDPSEPRKVVTCASYEAREFGVHAGMPLRAAARRCPDATFLPSDPAAYDEASEQVMGLLRDLGHPLEVWGWDEAYLGADLPDESDPVEVAERIRTVVAAETGLSCSVGISDNKQRAKVATGFAKPAGIYVLTEANWMTVMGDRPPDALWGVGPKTTKKLAAMGITTVADLAVTDPSVLTTAFGPSTGLWLLLLAKGGGDTEVSSEPWVPRSRSHVVTFPQDLTERREMDSAVRDLALQTLAEIVEQGRIVTRVAVTVRTSTFYTRTKIRKLPAPSTDAGQIVDTALAVLDQFELDRPVRLLGVRLELAMDDVPRPAVTAGT

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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