MSMEG1011
ms1011
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M. smegmatis · MC2-155
[AlphaFold] [Orthologs] [UniProt] [MycoBrowser] [TnSeq DB] [SeqHub]
MC2-155 Coordinates: 1080585 – 1081448
Vulnerability Index (VI):
M. tuberculosis homologs Rv3057c, Rv0851c, Rv3085, Rv2766c, Rv0765c, [+ 17 remaining orthologs]
M. abscessus homologs MAB3420c, MAB4680c, MAB0090c, MAB3919c, MAB4019c, [+ 37 remaining orthologs]
background  +5   0  -5 -10 -15 sgRNA L2FC (+ATc/–ATc) TnSeq Gene Essentiality Predictions (1, 2) Essential Growth Defect Non-Essential Growth Advantage Unknown Operon Legend (3) Operon (1) PMID: 28096490 (2) PMID: 31388080 (3) PMID: 26536359 MSMEG1008 MSMEG1009 MSMEG1010 MSMEG1011 MSMEG1012 MSMEG1013 dinB
Click the tabs above to view different types of data for this gene. The Vulnerability tab shows CRISPRi fitness data.
DNA and Protein Sequence help

DNA Sequence 

>ms1011_MSMEG1011_dna
ACCGTCGCGCAGAACACCGACGCGCAGATCCGCGACATCATGAACGACTTCGAGGACGCCACGATCGCCAAGATCGTCGGCGTCATCGAACAGGACACCGGAGCCCGGCCGATCTCCGACGATCTGCCCGCACTGGTGCGCACCCTGACCGCGACCACGGCGATGACACTGTCGCGTGACGCCGGGTTCGTGGGCCGTGACGCCGATCCCGCGCGTGCCGTCGAGATCGTCGAACGCCTGTGGCTCAGCGCGCTGTGGGGTGGCCTGCCGGAGTAGATCTCCCCGGTAAGGTCACCGCTATGGCGCAGGGGAGCGACTTCGCGGGCAAGAGATGTTTCGTGACCGGGGCGGCCAGCGGCATCGGCCGCGCCACGGCGCTGGCGCTCGCCGCGGCGGGCGCCGAGCTCTACCTGACCGACCGCGACGCCGACGGGCTTGTGCAGACCGTCGCCGATGCGCGCGCGCTCGGCGCCGAGGTGCCTGCGCACCGCGCGCTCGACATCTCCGACTACGACCAAGTGCGCGAGTTCGCCAAGGACATCCACGCCGCGCACGGGTCGATGGACGTCGTGATGAACATCGCGGGCGTGTCCGCGTGGGGCACCGTCGACCGGCTCAGTCACCAGCAGTGGCGGTCGATGGTCGACATCAACCTCATGGGGCCCATCCACGTCATCGAGGAGTTCATCCCGCCGATGATCGAGGCGCGCCGCGGCGGGCACCTGGTCAACGTGTCCTCGGCGGCCGGTCTGGTCGCCCTGCCGTGGCACGGTGCCTACAGCGCAAGCAAATTCGGCCTGCGCGGCGTGAGCGAGGTGCTGCGATTCGACCTGGCGCGACACCGCATCGGGGTGTCGGTGGTGGTGCCCGGCGCCGTGAAGACCGGCCTGGTGCAGACCGTCGAGATCGCCGGCGTCGACCGCGAGGACCCCGACGTCAAGAAGTGGGTGGATCGCTTTGCCGGACATGCGATCTCACCTGAGAAGGCCGCCGCGAAGATCCTGGCGGGGGTACGACGCAACCGGTTTTTGATCTACACCTCGGCCGACATCCGCGCGCTGTACACGTTCAAGCGCGTGGCCTGGTGGCCCTACAGCGTGGCGATGCGCCAGGTGAACGTGCTGTTCACCCGCGCTCTGCGCTCCGGCACATCGCCACGCTGA

Protein Sequence 

>Ms1011_MSMEG1011_protein
MAQGSDFAGKRCFVTGAASGIGRATALALAAAGAELYLTDRDADGLVQTVADARALGAEVPAHRALDISDYDQVREFAKDIHAAHGSMDVVMNIAGVSAWGTVDRLSHQQWRSMVDINLMGPIHVIEEFIPPMIEARRGGHLVNVSSAAGLVALPWHGAYSASKFGLRGVSEVLRFDLARHRIGVSVVVPGAVKTGLVQTVEIAGVDREDPDVKKWVDRFAGHAISPEKAAAKILAGVRRNRFLIYTSADIRALYTFKRVAWWPYSVAMRQVNVLFTRALRSGTSPR

Essentiality:

Call Condition Type Source Notes
Unknown in vitro CRISPRi [Bosch & DeJesus et al. (2021)]
Growth Advantage in vitro TnSeq [Dragset et al. (2019)]

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